dut-1

Summary

Gene Symbol: dut-1
Description: DeoxyUTPase
Alias: DeoxyUTPase
Species: Caenorhabditis elegans

Top Publications

  1. Zakaria C, Kassahun H, Yang X, Labbé J, Nilsen H, Ramotar D. Caenorhabditis elegans APN-1 plays a vital role in maintaining genome stability. DNA Repair (Amst). 2010;9:169-76 pubmed publisher
    ..Finally, we showed that depletion of APN-1 by RNAi partially rescued the lethality resulting from uracil misincorporation, suggesting that APN-1 is an important AP endonuclease for repair of misincorporated uracil. ..
  2. Erdélyi P, Borsos E, Takacs Vellai K, Kovacs T, Kovacs A, Sigmond T, et al. Shared developmental roles and transcriptional control of autophagy and apoptosis in Caenorhabditis elegans. J Cell Sci. 2011;124:1510-8 pubmed publisher
    ..The identification of apoptosis and autophagy as compensatory cellular pathways in C. elegans might help us to understand how dysregulated PCD in humans can lead to diverse pathologies, including cancer, neurodegeneration and diabetes. ..