deg-3

Summary

Gene Symbol: deg-3
Description: Acetylcholine receptor subunit alpha-type deg-3
Alias: Acetylcholine receptor subunit alpha-type deg-3
Species: Caenorhabditis elegans

Top Publications

  1. Syntichaki P, Samara C, Tavernarakis N. The vacuolar H+ -ATPase mediates intracellular acidification required for neurodegeneration in C. elegans. Curr Biol. 2005;15:1249-54 pubmed
    ..Similar mechanisms may contribute to necrotic cell death that follows extreme acidosis-for example, during stroke-in humans. ..
  2. Cohen Ben Ami H, Biala Y, Farah H, Elishevitz E, Battat E, Treinin M. Receptor and subunit specific interactions of RIC-3 with nicotinic acetylcholine receptors. Biochemistry. 2009;48:12329-36 pubmed publisher
    ..Such differences may explain both the effects of RIC-3 on receptor properties and the differences in its effects on different receptors. ..
  3. Ben Ami H, Yassin L, Farah H, Michaeli A, Eshel M, Treinin M. RIC-3 affects properties and quantity of nicotinic acetylcholine receptors via a mechanism that does not require the coiled-coil domains. J Biol Chem. 2005;280:28053-60 pubmed
    ..Together our results suggest that subunit-specific interactions of RIC-3 with nAChR subunits, mediated by the transmembrane domains, are sufficient for the effects of RIC-3 on nAChR quantity and quality. ..