Gene Symbol: dct-17
Description: DAF-16/FOXO Controlled, germline Tumor affecting
Alias: DAF-16/FOXO Controlled, germline Tumor affecting
Species: Caenorhabditis elegans

Top Publications

  1. Evans E, Kawli T, Tan M. Pseudomonas aeruginosa suppresses host immunity by activating the DAF-2 insulin-like signaling pathway in Caenorhabditis elegans. PLoS Pathog. 2008;4:e1000175 pubmed publisher
    ..Our results reveal a new mechanism by which P. aeruginosa suppresses host immune defense. ..
  2. Anderson E, Corkins M, Li J, Singh K, Parsons S, Tucey T, et al. C. elegans lifespan extension by osmotic stress requires FUdR, base excision repair, FOXO, and sirtuins. Mech Ageing Dev. 2016;154:30-42 pubmed publisher
    ..C. elegans lifespan studies using FUdR may need re-interpretation in light of this work. ..
  3. Shi Y, Pan T, Liao V. Monascin from Monascus-Fermented Products Reduces Oxidative Stress and Amyloid-? Toxicity via DAF-16/FOXO in Caenorhabditis elegans. J Agric Food Chem. 2016;64:7114-20 pubmed publisher
    ..The findings indicate that MS reduces oxidative stress and A? toxicity via DAF-16 in C. elegans, suggesting that MS can be used for the prevention of AD-associated oxidative stress complications. ..
  4. Nandakumar M, Tan M. Gamma-linolenic and stearidonic acids are required for basal immunity in Caenorhabditis elegans through their effects on p38 MAP kinase activity. PLoS Genet. 2008;4:e1000273 pubmed publisher
    ..The conservation of p38 MAP kinase signaling in both stress and immune responses further encourages exploring the function of GLA and SDA in humans. ..
  5. Zhang T, Baldie G, Periz G, Wang J. RNA-processing protein TDP-43 regulates FOXO-dependent protein quality control in stress response. PLoS Genet. 2014;10:e1004693 pubmed publisher
    ..The results suggest that compromising the function of TDP-43 in regulating protein homeostasis may contribute to the pathogenesis of related neurodegenerative diseases. ..