daf-6

Summary

Gene Symbol: daf-6
Description: hypothetical protein
Species: Caenorhabditis elegans

Top Publications

  1. Perkins L, Hedgecock E, Thomson J, Culotti J. Mutant sensory cilia in the nematode Caenorhabditis elegans. Dev Biol. 1986;117:456-87 pubmed
    ..The cat-6 (e1861) mutation disrupts the tubular bodies of the CEP mechanocilia. A cryophilic thermotaxis mutant, ttx-1 (p767), lacks fingers on the AFD dendrite, suggesting this neuron is thermosensory. ..
  2. Perens E, Shaham S. C. elegans daf-6 encodes a patched-related protein required for lumen formation. Dev Cell. 2005;8:893-906 pubmed
    ..We propose that amphid lumen morphogenesis is coordinated by neuron-derived cues and a DAF-6/CHE-14 system that regulates vesicle dynamics during tubulogenesis...
  3. Starich T, Herman R, Kari C, Yeh W, Schackwitz W, Schuyler M, et al. Mutations affecting the chemosensory neurons of Caenorhabditis elegans. Genetics. 1995;139:171-88 pubmed
    ..We have assigned 20 mutations to 13 new genes, called dyf-1 through dyf-13. We expect that the genes represented by dye-filing defective mutants are important for the differentiation of amphid and phasmid chemosensilla. ..
  4. Golden J, Riddle D. A pheromone-induced developmental switch in Caenorhabditis elegans: Temperature-sensitive mutants reveal a wild-type temperature-dependent process. Proc Natl Acad Sci U S A. 1984;81:819-23 pubmed
    ..These mutations appear to indirectly result in a ts phenotype by enhancing the expression of a wild-type ts developmental process. ..
  5. Moussaif M, Sze J. Intraflagellar transport/Hedgehog-related signaling components couple sensory cilium morphology and serotonin biosynthesis in Caenorhabditis elegans. J Neurosci. 2009;29:4065-75 pubmed publisher
    ..elegans under stress and stress recovery...
  6. Oikonomou G, Perens E, Lu Y, Watanabe S, Jorgensen E, Shaham S. Opposing activities of LIT-1/NLK and DAF-6/patched-related direct sensory compartment morphogenesis in C. elegans. PLoS Biol. 2011;9:e1001121 pubmed publisher
    ..Our results suggest that the opposing daf-6 and lit-1 glial pathways act together to control sensory compartment size. ..
  7. Lin K, Hsin H, Libina N, Kenyon C. Regulation of the Caenorhabditis elegans longevity protein DAF-16 by insulin/IGF-1 and germline signaling. Nat Genet. 2001;28:139-45 pubmed
    ..Together these findings reveal unexpected complexity in the DAF-16-dependent pathways that regulate aging. ..