daf-14

Summary

Gene Symbol: daf-14
Description: hypothetical protein
Species: Caenorhabditis elegans

Top Publications

  1. Vowels J, Thomas J. Genetic analysis of chemosensory control of dauer formation in Caenorhabditis elegans. Genetics. 1992;130:105-23 pubmed
    ..These results suggest that daf-11 is directly involved in chemosensory transduction essential for dauer formation, while the other Daf-c genes play roles downstream of the chemosensory step. ..
  2. Golden J, Riddle D. A pheromone-induced developmental switch in Caenorhabditis elegans: Temperature-sensitive mutants reveal a wild-type temperature-dependent process. Proc Natl Acad Sci U S A. 1984;81:819-23 pubmed
    ..These mutations appear to indirectly result in a ts phenotype by enhancing the expression of a wild-type ts developmental process. ..
  3. Schackwitz W, Inoue T, Thomas J. Chemosensory neurons function in parallel to mediate a pheromone response in C. elegans. Neuron. 1996;17:719-28 pubmed
    ..Mutations in the second genetic pathway activate dauer formation in an ASJ-dependent manner. Thus, the genetic redundancy in this process is reflected at the neuronal level. ..
  4. Shaw W, Luo S, Landis J, Ashraf J, Murphy C. The C. elegans TGF-beta Dauer pathway regulates longevity via insulin signaling. Curr Biol. 2007;17:1635-45 pubmed
    ..Together, our results suggest there are TGF-beta-specific downstream targets and functions, but that the TGF-beta and IIS pathways might be more tightly linked in the regulation of longevity than has been previously appreciated. ..
  5. Reddy K, Andersen E, Kruglyak L, Kim D. A polymorphism in npr-1 is a behavioral determinant of pathogen susceptibility in C. elegans. Science. 2009;323:382-4 pubmed publisher
    ..For C. elegans, bacteria represent food but also a potential source of infection. Our data underscore the importance of behavioral responses to oxygen levels in finding an optimal balance between these potentially conflicting cues. ..
  6. Inoue T, Thomas J. Targets of TGF-beta signaling in Caenorhabditis elegans dauer formation. Dev Biol. 2000;217:192-204 pubmed
    ..Instead, these experiments suggest the nervous system as a target of DAF-7 signaling and that the nervous system in turn regulates dauer formation by other tissues. ..
  7. Li Y, Zhang Q, Wei Q, Zhang Y, Ling K, Hu J. SUMOylation of the small GTPase ARL-13 promotes ciliary targeting of sensory receptors. J Cell Biol. 2012;199:589-98 pubmed publisher
    ..Our data reveal a novel but conserved role for the SUMOylation modification of ciliary small GTPase ARL13B in specifically regulating the proper ciliary targeting of various sensory receptors. ..