daf-10

Summary

Gene Symbol: daf-10
Description: Intraflagellar transport protein 122 homolog
Alias: Intraflagellar transport protein 122 homolog
Species: Caenorhabditis elegans

Top Publications

  1. Perkins L, Hedgecock E, Thomson J, Culotti J. Mutant sensory cilia in the nematode Caenorhabditis elegans. Dev Biol. 1986;117:456-87 pubmed
    ..The cat-6 (e1861) mutation disrupts the tubular bodies of the CEP mechanocilia. A cryophilic thermotaxis mutant, ttx-1 (p767), lacks fingers on the AFD dendrite, suggesting this neuron is thermosensory. ..
  2. Starich T, Herman R, Kari C, Yeh W, Schackwitz W, Schuyler M, et al. Mutations affecting the chemosensory neurons of Caenorhabditis elegans. Genetics. 1995;139:171-88 pubmed
    ..We have assigned 20 mutations to 13 new genes, called dyf-1 through dyf-13. We expect that the genes represented by dye-filing defective mutants are important for the differentiation of amphid and phasmid chemosensilla. ..
  3. Bell L, Stone S, Yochem J, Shaw J, Herman R. The molecular identities of the Caenorhabditis elegans intraflagellar transport genes dyf-6, daf-10 and osm-1. Genetics. 2006;173:1275-86 pubmed
    ..Movement of DYF-6::GFP within the ciliated endings of the neurons indicates that DYF-6 is involved in IFT. In addition, IFT can be observed in dauer larvae. ..
  4. Golden J, Riddle D. A pheromone-induced developmental switch in Caenorhabditis elegans: Temperature-sensitive mutants reveal a wild-type temperature-dependent process. Proc Natl Acad Sci U S A. 1984;81:819-23 pubmed
    ..These mutations appear to indirectly result in a ts phenotype by enhancing the expression of a wild-type ts developmental process. ..
  5. Barr M, Sternberg P. A polycystic kidney-disease gene homologue required for male mating behaviour in C. elegans. Nature. 1999;401:386-9 pubmed
    ..PKD-2, the C. elegans homologue of PKD2, is localized to the same neurons as LOV-1, suggesting that they function in the same pathway...
  6. Lin K, Hsin H, Libina N, Kenyon C. Regulation of the Caenorhabditis elegans longevity protein DAF-16 by insulin/IGF-1 and germline signaling. Nat Genet. 2001;28:139-45 pubmed
    ..Together these findings reveal unexpected complexity in the DAF-16-dependent pathways that regulate aging. ..
  7. Jensen V, Bialas N, Bishop Hurley S, Molday L, Kida K, Nguyen P, et al. Localization of a guanylyl cyclase to chemosensory cilia requires the novel ciliary MYND domain protein DAF-25. PLoS Genet. 2010;6:e1001199 pubmed publisher
    ..In summary, we have discovered a novel ciliary protein that plays an important role in cGMP signaling by localizing a guanylyl cyclase to the sensory organelle. ..
  8. Vowels J, Thomas J. Genetic analysis of chemosensory control of dauer formation in Caenorhabditis elegans. Genetics. 1992;130:105-23 pubmed
    ..These results suggest that daf-11 is directly involved in chemosensory transduction essential for dauer formation, while the other Daf-c genes play roles downstream of the chemosensory step. ..
  9. Brear A, Yoon J, Wojtyniak M, Sengupta P. Diverse cell type-specific mechanisms localize G protein-coupled receptors to Caenorhabditis elegans sensory cilia. Genetics. 2014;197:667-84 pubmed publisher