csnk-1

Summary

Gene Symbol: csnk-1
Description: Casein kinase I gamma
Alias: Casein kinase I gamma
Species: Caenorhabditis elegans

Top Publications

  1. Sieburth D, Ch ng Q, Dybbs M, Tavazoie M, Kennedy S, Wang D, et al. Systematic analysis of genes required for synapse structure and function. Nature. 2005;436:510-7 pubmed
    ..Twenty-four genes encoded proteins that were localized to presynaptic specializations. Loss-of-function mutations in 12 genes caused defects in presynaptic structure...
  2. Panbianco C, Weinkove D, Zanin E, Jones D, Divecha N, Gotta M, et al. A casein kinase 1 and PAR proteins regulate asymmetry of a PIP(2) synthesis enzyme for asymmetric spindle positioning. Dev Cell. 2008;15:198-208 pubmed publisher
    ..Furthermore, loss of CSNK-1 leads to increased levels of PIP(2). We propose that asymmetric generation of PIP(2) by PPK-1 directs the posterior enrichment of GPR-1/2 and LIN-5, leading to posterior spindle displacement. ..