Gene Symbol: cpf-1
Description: Cleavage and Polyadenylation Factor
Alias: Cleavage and Polyadenylation Factor
Species: Caenorhabditis elegans

Top Publications

  1. McCracken S, Longman D, Johnstone I, Caceres J, Blencowe B. An evolutionarily conserved role for SRm160 in 3'-end processing that functions independently of exon junction complex formation. J Biol Chem. 2003;278:44153-60 pubmed
    ..Our combined results provide evidence for an evolutionarily conserved interaction between SRm160 and the 3'-end cleavage machinery that functions independently of EJC formation. ..
  2. Fortes P, Longman D, McCracken S, Ip J, Poot R, Mattaj I, et al. Identification and characterization of RED120: a conserved PWI domain protein with links to splicing and 3'-end formation. FEBS Lett. 2007;581:3087-97 pubmed
    ..These results suggest that RED120 may function to couple splicing with mRNA 3'-end formation. ..
  3. Cui M, Allen M, Larsen A, MacMorris M, Han M, Blumenthal T. Genes involved in pre-mRNA 3'-end formation and transcription termination revealed by a lin-15 operon Muv suppressor screen. Proc Natl Acad Sci U S A. 2008;105:16665-70 pubmed publisher
    ..Furthermore, our results implicate a serine/arginine-rich (SR) protein, SRp20, in events following 3'-end cleavage, leading to termination of transcription. ..