chs 1


Gene Symbol: chs 1
Description: CHitin Synthase
Alias: CHitin Synthase
Species: Caenorhabditis elegans

Top Publications

  1. Johnston W, Krizus A, Dennis J. The eggshell is required for meiotic fidelity, polar-body extrusion and polarization of the C. elegans embryo. BMC Biol. 2006;4:35 pubmed
    ..of uridine diphosphate-N-acetylglucosamine (UDP-GlcNAc), the substrate for eggshell chitin synthesis by chitin synthase-1 (CHS-1). Furthermore, while chs-1(RNAi) or combined RNAi with the chitin-binding proteins, CEJ-1 and B0280...
  2. Maruyama R, Velarde N, Klancer R, Gordon S, Kadandale P, Parry J, et al. EGG-3 regulates cell-surface and cortex rearrangements during egg activation in Caenorhabditis elegans. Curr Biol. 2007;17:1555-60 pubmed
    ..Therefore, EGG-3 plays a central role in egg activation by influencing polarized F-actin dynamics and the localization or activity of molecules that are directly involved in executing the egg-to-embryo transition. ..
  3. Zhang Y, Foster J, Nelson L, Ma D, Carlow C. The chitin synthase genes chs-1 and chs-2 are essential for C. elegans development and responsible for chitin deposition in the eggshell and pharynx, respectively. Dev Biol. 2005;285:330-9 pubmed
    ..Here, we determined the roles of chitin and the two predicted chitin synthase genes in Caenorhabditis elegans by chitin localization and gene disruption...
  4. Veronico P, Gray L, Jones J, Bazzicalupo P, Arbucci S, Cortese M, et al. Nematode chitin synthases: gene structure, expression and function in Caenorhabditis elegans and the plant parasitic nematode Meloidogyne artiellia. Mol Genet Genomics. 2001;266:28-34 pubmed
    ..We have also isolated a full-length genomic sequence of a chitin synthase orthologue from the plant parasitic nematode Meloidogyne artiellia. The single gene present in M...
  5. Parry J, Velarde N, Lefkovith A, Zegarek M, Hang J, Ohm J, et al. EGG-4 and EGG-5 Link Events of the Oocyte-to-Embryo Transition with Meiotic Progression in C. elegans. Curr Biol. 2009;19:1752-7 pubmed publisher
    ..Therefore, EGG-4 and EGG-5 are not only required for critical events of the oocyte-to-embryo transition but also link the dynamics of the regulatory machinery with the advancing cell cycle. ..
  6. Olson S, Greenan G, Desai A, MULLER REICHERT T, Oegema K. Hierarchical assembly of the eggshell and permeability barrier in C. elegans. J Cell Biol. 2012;198:731-48 pubmed publisher
    ..The switch between the chitin and proteoglycan layers was achieved by internalization of chitin synthase coincident with exocytosis of proteoglycan-containing cortical granules...