che 1


Gene Symbol: che 1
Description: Transcription factor che-1;hypothetical protein
Alias: Transcription factor che-1;hypothetical protein
Species: Caenorhabditis elegans

Top Publications

  1. Uchida O, Nakano H, Koga M, Ohshima Y. The C. elegans che-1 gene encodes a zinc finger transcription factor required for specification of the ASE chemosensory neurons. Development. 2003;130:1215-24 pubmed
    ..Ectopic expression of che-1 cDNA induced expression of ASE-specific marker genes, a dye-filling defect in neurons other than ASE and dauer formation. ..
  2. Etchberger J, Lorch A, Sleumer M, Zapf R, Jones S, Marra M, et al. The molecular signature and cis-regulatory architecture of a C. elegans gustatory neuron. Genes Dev. 2007;21:1653-74 pubmed
    ..Taken together, our results provide a unique view of the molecular landscape of a single neuron type and reveal an important aspect of the regulatory logic for gustatory neuron specification in C. elegans. ..
  3. Etchberger J, Flowers E, Poole R, Bashllari E, Hobert O. Cis-regulatory mechanisms of left/right asymmetric neuron-subtype specification in C. elegans. Development. 2009;136:147-60 pubmed publisher
    ..It also suggests that feed-forward loop motifs may be a prominent feature of neuronal diversification events. ..
  4. O Meara M, Bigelow H, Flibotte S, Etchberger J, Moerman D, Hobert O. Cis-regulatory mutations in the Caenorhabditis elegans homeobox gene locus cog-1 affect neuronal development. Genetics. 2009;181:1679-86 pubmed publisher
    ..The multiplicity of cis-regulatory elements may ensure the robustness of gene expression. ..
  5. Ortiz C, Faumont S, Takayama J, Ahmed H, Goldsmith A, Pocock R, et al. Lateralized gustatory behavior of C. elegans is controlled by specific receptor-type guanylyl cyclases. Curr Biol. 2009;19:996-1004 pubmed publisher
    ..Our findings broaden our understanding of lateralities in neural function, provide insights into how this laterality is molecularly encoded, and reveal an unusual multitude of molecules involved in gustatory signal transduction. ..
  6. Tursun B, Patel T, Kratsios P, Hobert O. Direct conversion of C. elegans germ cells into specific neuron types. Science. 2011;331:304-8 pubmed publisher
    ..Our findings illustrate the ability of germ cells to be directly converted into individual, terminally differentiated neuron types and demonstrate that a specific chromatin factor provides a barrier for cellular reprogramming...
  7. Murayama T, Takayama J, Fujiwara M, Maruyama I. Environmental alkalinity sensing mediated by the transmembrane guanylyl cyclase GCY-14 in C. elegans. Curr Biol. 2013;23:1007-12 pubmed publisher
    ..These results argue that in addition to ion channels and GPCRs, RGCs also play a role in pH sensation in neurons...
  8. Adachi T, Kunitomo H, Tomioka M, Ohno H, Okochi Y, Mori I, et al. Reversal of salt preference is directed by the insulin/PI3K and Gq/PKC signaling in Caenorhabditis elegans. Genetics. 2010;186:1309-19 pubmed publisher
    ..A putative salt receptor GCY-22 guanylyl cyclase is required in ASER for both salt attraction and avoidance. Our results suggest that ASEL and ASER use distinct molecular mechanisms to regulate salt chemotaxis plasticity. ..