ceh 6

Summary

Gene Symbol: ceh 6
Description: Homeobox protein ceh-6
Alias: Homeobox protein ceh-6
Species: Caenorhabditis elegans

Top Publications

  1. Chen B, Liu Q, Ge Q, Xie J, Wang Z. UNC-1 regulates gap junctions important to locomotion in C. elegans. Curr Biol. 2007;17:1334-9 pubmed
    ..Thus, in addition to the recently reported function of regulating mechanosensitive ion channels [5, 6], SLPs might have a novel function of regulating gap junctions. ..
  2. Kagias K, Ahier A, Fischer N, Jarriault S. Members of the NODE (Nanog and Oct4-associated deacetylase) complex and SOX-2 promote the initiation of a natural cellular reprogramming event in vivo. Proc Natl Acad Sci U S A. 2012;109:6596-601 pubmed publisher
  3. Burglin T, Ruvkun G. Regulation of ectodermal and excretory function by the C. elegans POU homeobox gene ceh-6. Development. 2001;128:779-90 pubmed
    ..We propose that one evolutionary conserved function of the POU-III transcription factor class could be the regulation of genes that mediate secretion/osmoregulation. ..
  4. Mah A, Armstrong K, Chew D, Chu J, Tu D, Johnsen R, et al. Transcriptional regulation of AQP-8, a Caenorhabditis elegans aquaporin exclusively expressed in the excretory system, by the POU homeobox transcription factor CEH-6. J Biol Chem. 2007;282:28074-86 pubmed
    ..These parallels in transcriptional control between Brn1 and CEH-6 suggest that C. elegans may well be an appropriate model for determining gene-regulatory networks in the developing vertebrate kidney. ..
  5. Armstrong K, Chamberlin H. Coordinate regulation of gene expression in the C. elegans excretory cell by the POU domain protein CEH-6. Mol Genet Genomics. 2010;283:73-87 pubmed publisher
    ..This work suggests that a role for POU-III factors in renal organs is to coordinate the expression of a set of functionally related genes. ..
  6. Zuryn S, Ahier A, Portoso M, White E, Morin M, Margueron R, et al. Transdifferentiation. Sequential histone-modifying activities determine the robustness of transdifferentiation. Science. 2014;345:826-9 pubmed publisher
    ..Our results draw parallels between epigenetic mechanisms underlying robust Td in nature and efficient cell reprogramming in vitro. ..