Gene Symbol: cdka-1
Description: Cyclin-dependent kinase 5 activator 1
Alias: Cyclin-dependent kinase 5 activator 1
Species: Caenorhabditis elegans

Top Publications

  1. Locke C, Williams S, Schwarz E, Caldwell G, Caldwell K. Genetic interactions among cortical malformation genes that influence susceptibility to convulsions in C. elegans. Brain Res. 2006;1120:23-34 pubmed
    ..Thus, interactions among gene products with LIS-1 may mediate intrinsic thresholds of neuronal synchrony. ..
  2. Park E, GHOSE P, Shao Z, Ye Q, Kang L, Xu X, et al. Hypoxia regulates glutamate receptor trafficking through an HIF-independent mechanism. EMBO J. 2012;31:1379-93 pubmed publisher
    ..Our findings demonstrate a novel mechanism by which neurons sense and respond to hypoxia. ..
  3. Goodwin P, Sasaki J, Juo P. Cyclin-dependent kinase 5 regulates the polarized trafficking of neuropeptide-containing dense-core vesicles in Caenorhabditis elegans motor neurons. J Neurosci. 2012;32:8158-72 pubmed publisher
    ..We propose a model in which CDK-5 regulates DCV polarity by both promoting DCV trafficking in axons and preventing dynein-dependent DCV trafficking into dendrites. ..