Gene Symbol: cdd-1
Description: Cytidine deaminase
Alias: Cytidine deaminase
Species: Caenorhabditis elegans

Top Publications

  1. Thompson F, Britton C, Wheatley I, Maitland K, Walker G, Anant S, et al. Biochemical and molecular characterization of two cytidine deaminases in the nematode Caenorhabditis elegans. Biochem J. 2002;365:99-107 pubmed
    ..RNA-interference (RNAi) assays were performed for both genes, either alone or in combination, but only cdd-2 RNAi produced a consistent visible phenotype. A proportion of eggs laid from these worms were swollen and distorted in shape. ..
  2. Chi C, Ronai D, Than M, Walker C, Sewell A, Han M. Nucleotide levels regulate germline proliferation through modulating GLP-1/Notch signaling in C. elegans. Genes Dev. 2016;30:307-20 pubmed publisher
    ..Moreover, GLP-1 expression is post-transcriptionally modulated by U/T levels. Our results reveal a previously unknown nucleotide-sensing mechanism for controlling reproductivity. ..