Gene Symbol: bbs-1
Description: Bardet-Biedl syndrome 1 protein homolog
Alias: Bardet-Biedl syndrome 1 protein homolog
Species: Caenorhabditis elegans

Top Publications

  1. Ansley S, Badano J, Blacque O, Hill J, Hoskins B, Leitch C, et al. Basal body dysfunction is a likely cause of pleiotropic Bardet-Biedl syndrome. Nature. 2003;425:628-33 pubmed
  2. Blacque O, Reardon M, Li C, McCarthy J, Mahjoub M, Ansley S, et al. Loss of C. elegans BBS-7 and BBS-8 protein function results in cilia defects and compromised intraflagellar transport. Genes Dev. 2004;18:1630-42 pubmed
    ..Our findings also suggest that some of the cardinal and secondary symptoms of BBS, such as obesity, diabetes, cardiomyopathy, and learning defects may result from cilia dysfunction. ..