Gene Symbol: atf-7
Description: ATF (cAMP-dependent transcription factor) family
Alias: ATF (cAMP-dependent transcription factor) family
Species: Caenorhabditis elegans

Top Publications

  1. Shivers R, Pagano D, Kooistra T, Richardson C, Reddy K, Whitney J, et al. Phosphorylation of the conserved transcription factor ATF-7 by PMK-1 p38 MAPK regulates innate immunity in Caenorhabditis elegans. PLoS Genet. 2010;6:e1000892 pubmed publisher
  2. Chikka M, Anbalagan C, Dvorak K, Dombeck K, Prahlad V. The Mitochondria-Regulated Immune Pathway Activated in the C. elegans Intestine Is Neuroprotective. Cell Rep. 2016;16:2399-414 pubmed publisher
    ..We propose that mitochondria are subject to constant surveillance by innate immune mechanisms. ..
  3. Hall J, McElwee M, Freedman J. Identification of ATF-7 and the insulin signaling pathway in the regulation of metallothionein in C. elegans suggests roles in aging and reactive oxygen species. PLoS ONE. 2017;12:e0177432 pubmed publisher
    ..Identification of portions of the insulin signaling pathway as regulators of metallothionein expression supports the hypothesis that longevity is affected by the expression of this efficient ROS scavenger. ..