atf-2

Summary

Gene Symbol: atf-2
Description: ATF (cAMP-dependent transcription factor) family
Alias: ATF (cAMP-dependent transcription factor) family
Species: Caenorhabditis elegans

Top Publications

  1. Wang X, Jia H, Chamberlin H. The bZip proteins CES-2 and ATF-2 alter the timing of transcription for a cell-specific target gene in C. elegans. Dev Biol. 2006;289:456-65 pubmed
    ..Thus, the two bZip proteins function together as one of several inputs that influence the spatial and temporal regulation of lin-48. ..
  2. Lemieux G, Liu J, Mayer N, Bainton R, Ashrafi K, Werb Z. A whole-organism screen identifies new regulators of fat storage. Nat Chem Biol. 2011;7:206-13 pubmed publisher
    ..Thus, our strategy identifies small molecules that are effective within the context of intact animals and reveals relationships between new pathways that operate across phyla to influence energy homeostasis. ..
  3. Erdélyi P, Borsos E, Takacs Vellai K, Kovacs T, Kovacs A, Sigmond T, et al. Shared developmental roles and transcriptional control of autophagy and apoptosis in Caenorhabditis elegans. J Cell Sci. 2011;124:1510-8 pubmed publisher
    ..The identification of apoptosis and autophagy as compensatory cellular pathways in C. elegans might help us to understand how dysregulated PCD in humans can lead to diverse pathologies, including cancer, neurodegeneration and diabetes. ..