Gene Symbol: aspm-1
Description: hypothetical protein
Species: Caenorhabditis elegans

Top Publications

  1. van der Voet M, Berends C, Perreault A, Nguyen Ngoc T, GONCZY P, Vidal M, et al. NuMA-related LIN-5, ASPM-1, calmodulin and dynein promote meiotic spindle rotation independently of cortical LIN-5/GPR/Galpha. Nat Cell Biol. 2009;11:269-77 pubmed publisher
    ..These functional interactions may be conserved in mammals, with implications for primary microcephaly. ..
  2. Connolly A, Osterberg V, Christensen S, Price M, Lu C, Chicas Cruz K, et al. Caenorhabditis elegans oocyte meiotic spindle pole assembly requires microtubule severing and the calponin homology domain protein ASPM-1. Mol Biol Cell. 2014;25:1298-311 pubmed publisher
    ..We conclude that microtubule severing and ASPM-1 both promote meiotic spindle pole assembly in C. elegans oocytes, whereas the kinesin 12 family member KLP-18 promotes spindle bipolarity. ..