Gene Symbol: arf-6
Description: ADP-Ribosylation Factor related
Alias: ADP-Ribosylation Factor related
Species: Caenorhabditis elegans

Top Publications

  1. Dang H, Li Z, Skolnik E, Fares H. Disease-related myotubularins function in endocytic traffic in Caenorhabditis elegans. Mol Biol Cell. 2004;15:189-96 pubmed
    ..We demonstrate that MTM-6 and MTM-9 function as part of a complex to regulate an endocytic pathway that involves the Arf6 GTPase, and we define protein domains required for MTM-6 activity. ..
  2. Singhvi A, Teulière J, Talavera K, Cordes S, Ou G, Vale R, et al. The Arf GAP CNT-2 regulates the apoptotic fate in C. elegans asymmetric neuroblast divisions. Curr Biol. 2011;21:948-54 pubmed publisher
    ..We provide evidence that CNT-2 regulates receptor-mediated endocytosis and consider the implications of its role in asymmetric cell divisions. ..
  3. Shi A, Liu O, Koenig S, Banerjee R, Chen C, Eimer S, et al. RAB-10-GTPase-mediated regulation of endosomal phosphatidylinositol-4,5-bisphosphate. Proc Natl Acad Sci U S A. 2012;109:E2306-15 pubmed publisher
    ..Our studies identify a RAB-10-to-ARF-6 regulatory loop required to regulate endosomal PI(4,5)P2, a key phosphoinositide in membrane traffic. ..
  4. Li Y, Kelly W, Logsdon J, Schurko A, Harfe B, Hill Harfe K, et al. Functional genomic analysis of the ADP-ribosylation factor family of GTPases: phylogeny among diverse eukaryotes and function in C. elegans. FASEB J. 2004;18:1834-50 pubmed
    ..elegans, at least three are required for embryogenesis. These data represent the first analysis of the role(s) of multiple members of this family in the development of a multicellular organism. ..