Gene Symbol: arf-1.2
Description: ADP-ribosylation factor 1-like 2
Alias: ADP-ribosylation factor 1-like 2
Species: Caenorhabditis elegans
Singhvi A, Teulière J, Talavera K, Cordes S, Ou G, Vale R, et al
. The Arf GAP CNT-2 regulates the apoptotic fate in C. elegans asymmetric neuroblast divisions. Curr Biol. 2011;21:948-54 pubmed publisher
..We provide evidence that CNT-2 regulates receptor-mediated endocytosis and consider the implications of its role in asymmetric cell divisions. ..
Ackema K, Hench J, BÃ¶ckler S, Wang S, Sauder U, Mergentaler H, et al
. The small GTPase Arf1 modulates mitochondrial morphology and function. EMBO J. 2014;33:2659-75 pubmed publisher
..Thus, Arf1 is involved in mitochondrial homeostasis and dynamics, independent of its role in vesicular traffic. ..
Grant B, Hirsh D. Receptor-mediated endocytosis in the Caenorhabditis elegans oocyte. Mol Biol Cell. 1999;10:4311-26 pubmed
..We describe a new member of the low-density lipoprotein receptor superfamily, RME-2, identified in our screens for endocytosis defective mutants. We show that RME-2 is the C. elegans yolk receptor. ..
Li Y, Kelly W, Logsdon J, Schurko A, Harfe B, Hill Harfe K, et al
. Functional genomic analysis of the ADP-ribosylation factor family of GTPases: phylogeny among diverse eukaryotes and function in C. elegans. FASEB J. 2004;18:1834-50 pubmed
..elegans, at least three are required for embryogenesis. These data represent the first analysis of the role(s) of multiple members of this family in the development of a multicellular organism. ..
Poteryaev D, Squirrell J, Campbell J, White J, Spang A. Involvement of the actin cytoskeleton and homotypic membrane fusion in ER dynamics in Caenorhabditis elegans. Mol Biol Cell. 2005;16:2139-53 pubmed
..Both proteins have been implicated in homotypic ER membrane fusion. We provide evidence that homotypic membrane fusion is required to form the sheet structure in the early embryo. ..
Denning D, Hatch V, Horvitz H. Programmed elimination of cells by caspase-independent cell extrusion in C. elegans. Nature. 2012;488:226-30 pubmed publisher
..Our findings reveal a mechanism for apoptotic cell elimination that is fundamentally distinct from that of canonical programmed cell death. ..