apc-2

Summary

Gene Symbol: apc-2
Description: Anaphase-promoting complex subunit 2
Alias: Anaphase-promoting complex subunit 2
Species: Caenorhabditis elegans

Top Publications

  1. Davis E, Wille L, Chestnut B, Sadler P, Shakes D, Golden A. Multiple subunits of the Caenorhabditis elegans anaphase-promoting complex are required for chromosome segregation during meiosis I. Genetics. 2002;160:805-13 pubmed
    ..Further, chromosome segregation during meiosis I requires APC/C functions in addition to the release of sister chromatid cohesion. ..
  2. Capron A, Serralbo O, Fulop K, Frugier F, Parmentier Y, Dong A, et al. The Arabidopsis anaphase-promoting complex or cyclosome: molecular and genetic characterization of the APC2 subunit. Plant Cell. 2003;15:2370-82 pubmed
    ..Finally, we report intriguing differences in APC2 protein subcellular localization compared with that in other systems. Our observations support a conserved function of the APC/C in plants but a different mode of regulation. ..
  3. Ellefson M, McNally F. Kinesin-1 and cytoplasmic dynein act sequentially to move the meiotic spindle to the oocyte cortex in Caenorhabditis elegans. Mol Biol Cell. 2009;20:2722-30 pubmed publisher
    ..This represents a case of kinesin-1/dynein coordination in which these two motors of opposite polarity act sequentially and independently on a cargo to move it in the same direction. ..