Gene Symbol: aipl-1
Description: AIP1 (Actin Interacting Protein 1) Like
Alias: AIP1 (Actin Interacting Protein 1) Like
Species: Caenorhabditis elegans

Top Publications

  1. Tischler J, Lehner B, Chen N, Fraser A. Combinatorial RNA interference in Caenorhabditis elegans reveals that redundancy between gene duplicates can be maintained for more than 80 million years of evolution. Genome Biol. 2006;7:R69 pubmed
  2. Nomura K, Hayakawa K, Tatsumi H, Ono S. Actin-interacting Protein 1 Promotes Disassembly of Actin-depolymerizing Factor/Cofilin-bound Actin Filaments in a pH-dependent Manner. J Biol Chem. 2016;291:5146-56 pubmed publisher
    ..These biochemical results suggest that pH-dependent changes in AIP1 activity might be a novel regulatory mechanism of actin filament dynamics. ..
  3. Ono S, Nomura K, Hitosugi S, Tu D, Lee J, Baillie D, et al. The two actin-interacting protein 1 genes have overlapping and essential function for embryonic development in Caenorhabditis elegans. Mol Biol Cell. 2011;22:2258-69 pubmed publisher
    ..Thus our results suggest that enhancement of actin filament disassembly by ADF/cofilin and AIP1 proteins is critical for embryogenesis. ..