Gene Symbol: aff-1
Description: Cell fusion protein aff-1
Alias: Cell fusion protein aff-1
Species: Caenorhabditis elegans

Top Publications

  1. Sapir A, Choi J, Leikina E, Avinoam O, Valansi C, Chernomordik L, et al. AFF-1, a FOS-1-regulated fusogen, mediates fusion of the anchor cell in C. elegans. Dev Cell. 2007;12:683-98 pubmed
    ..Thus, FOS-1 links cell invasion and fusion in a developmental cascade. ..
  2. Avinoam O, Fridman K, Valansi C, Abutbul I, Zeev Ben Mordehai T, Maurer U, et al. Conserved eukaryotic fusogens can fuse viral envelopes to cells. Science. 2011;332:589-92 pubmed publisher
    ..Thus, FF proteins are part of an ancient family of cellular fusogens that can promote fusion when expressed on a viral particle. ..
  3. Oren Suissa M, Gattegno T, Kravtsov V, Podbilewicz B. Extrinsic Repair of Injured Dendrites as a Paradigm for Regeneration by Fusion in Caenorhabditis elegans. Genetics. 2017;206:215-230 pubmed publisher
    ..EFF-1 is essential for dendritic pruning after injury and extrinsic AFF-1 mediates dendrite fusion to bypass injuries. ..