acr 2


Gene Symbol: acr 2
Description: Acetylcholine receptor subunit beta-type acr-2
Alias: Acetylcholine receptor subunit beta-type acr-2
Species: Caenorhabditis elegans

Top Publications

  1. Squire M, Tornøe C, Baylis H, Fleming J, Barnard E, Sattelle D. Molecular cloning and functional co-expression of a Caenorhabditis elegans nicotinic acetylcholine receptor subunit (acr-2). Receptors Channels. 1995;3:107-15 pubmed
  2. Jospin M, Qi Y, Stawicki T, Boulin T, Schuske K, Horvitz H, et al. A neuronal acetylcholine receptor regulates the balance of muscle excitation and inhibition in Caenorhabditis elegans. PLoS Biol. 2009;7:e1000265 pubmed publisher
    ..These data indicate that the ACR-2 receptor is important for the coordinated excitation and inhibition of body muscles underlying sinusoidal movement. ..
  3. Stawicki T, Zhou K, Yochem J, Chen L, Jin Y. TRPM channels modulate epileptic-like convulsions via systemic ion homeostasis. Curr Biol. 2011;21:883-8 pubmed publisher
    ..Together, these data reveal an important role for ion homeostasis in the balance of neuronal network activity and a novel function of nonneuronal TRPM channels in the fine-tuning of this network activity. ..
  4. Barbagallo B, Prescott H, Boyle P, Climer J, Francis M. A dominant mutation in a neuronal acetylcholine receptor subunit leads to motor neuron degeneration in Caenorhabditis elegans. J Neurosci. 2010;30:13932-42 pubmed publisher
  5. Qi Y, Po M, Mac P, Kawano T, Jorgensen E, Zhen M, et al. Hyperactivation of B-type motor neurons results in aberrant synchrony of the Caenorhabditis elegans motor circuit. J Neurosci. 2013;33:5319-25 pubmed publisher
    ..These results support that the activity state of B motor neurons plays an instructive role for the coordination of motor circuit. ..
  6. Stawicki T, Takayanagi Kiya S, Zhou K, Jin Y. Neuropeptides function in a homeostatic manner to modulate excitation-inhibition imbalance in C. elegans. PLoS Genet. 2013;9:e1003472 pubmed publisher