dbpB

Summary

Gene Symbol: dbpB
Description: decorin-binding protein B
Species: Borrelia burgdorferi B31

Top Publications

  1. pmc Adherence of Borrelia burgdorferi to the proteoglycan decorin
    B P Guo
    Department of Biochemistry and Biophysics, Albert B Alkek Institute of Biosciences and Technology, Texas A and M University, Houston 77030, USA
    Infect Immun 63:3467-72. 1995
  2. pmc Humoral immunity to Borrelia burgdorferi N40 decorin binding proteins during infection of laboratory mice
    S Feng
    Center for Comparative Medicine, Schools of Medicine and Veterinary Medicine, University of California, Davis, California 95616, USA
    Infect Immun 66:2827-35. 1998
  3. ncbi Decorin-binding adhesins from Borrelia burgdorferi
    B P Guo
    Albert B Alkek Institute of Biosciences and Technology and the Department of Biochemistry and Biophysics, Texas A and M University, Houston 77030, USA
    Mol Microbiol 30:711-23. 1998
  4. pmc Decorin-binding protein A (DbpA) of Borrelia burgdorferi is not protective when immunized mice are challenged via tick infestation and correlates with the lack of DbpA expression by B. burgdorferi in ticks
    K E Hagman
    Department of Microbiology, University of Texas Southwestern Medical Center, Dallas, Texas 75235, USA
    Infect Immun 68:4759-64. 2000
  5. pmc The dbpBA locus of Borrelia burgdorferi is not essential for infection of mice
    Yanlin Shi
    Department of Pathobiological Sciences, Louisiana State University, Skip Bertman Drive at River Road, Baton Rouge, LA 70803, USA
    Infect Immun 74:6509-12. 2006
  6. pmc Borrelia burgdorferi lacking DbpBA exhibits an early survival defect during experimental infection
    Eric H Weening
    Department of Microbial and Molecular Pathogenesis, College of Medicine, Texas A and M Health Science Center, College Station, TX 77843, USA
    Infect Immun 76:5694-705. 2008

Detail Information

Publications6

  1. pmc Adherence of Borrelia burgdorferi to the proteoglycan decorin
    B P Guo
    Department of Biochemistry and Biophysics, Albert B Alkek Institute of Biosciences and Technology, Texas A and M University, Houston 77030, USA
    Infect Immun 63:3467-72. 1995
    ..Our results indicate that decorin may mediate the adherence of B. burgdorferi to collagen fibers in skin and other tissues...
  2. pmc Humoral immunity to Borrelia burgdorferi N40 decorin binding proteins during infection of laboratory mice
    S Feng
    Center for Comparative Medicine, Schools of Medicine and Veterinary Medicine, University of California, Davis, California 95616, USA
    Infect Immun 66:2827-35. 1998
    ..These genes showed homology with the genes encoding decorin binding proteins DbpB and DbpA, respectively, of B. burgdorferi 297 and B31. N40-dbpA DNA hybridized with B...
  3. ncbi Decorin-binding adhesins from Borrelia burgdorferi
    B P Guo
    Albert B Alkek Institute of Biosciences and Technology and the Department of Biochemistry and Biophysics, Texas A and M University, Houston 77030, USA
    Mol Microbiol 30:711-23. 1998
    ..We have now cloned and sequenced two genes encoding the proteins, DbpA and DbpB, which have a similar structure, as revealed by circular dichroism (CD) spectroscopy of recombinant proteins...
  4. pmc Decorin-binding protein A (DbpA) of Borrelia burgdorferi is not protective when immunized mice are challenged via tick infestation and correlates with the lack of DbpA expression by B. burgdorferi in ticks
    K E Hagman
    Department of Microbiology, University of Texas Southwestern Medical Center, Dallas, Texas 75235, USA
    Infect Immun 68:4759-64. 2000
    ..The failure of DbpA immunization to protect tick-challenged mice contradicts the results of earlier needle inoculation vaccination experiments and suggests that DbpA may not be suitable as a Lyme disease vaccine...
  5. pmc The dbpBA locus of Borrelia burgdorferi is not essential for infection of mice
    Yanlin Shi
    Department of Pathobiological Sciences, Louisiana State University, Skip Bertman Drive at River Road, Baton Rouge, LA 70803, USA
    Infect Immun 74:6509-12. 2006
    ..burgdorferi expresses a broad array of adhesive molecules, including the decorin-binding proteins A and B (DbpA and DbpB), which are believed to play important roles in mammalian infection...
  6. pmc Borrelia burgdorferi lacking DbpBA exhibits an early survival defect during experimental infection
    Eric H Weening
    Department of Microbial and Molecular Pathogenesis, College of Medicine, Texas A and M Health Science Center, College Station, TX 77843, USA
    Infect Immun 76:5694-705. 2008
    ..burgdorferi and are required for optimal resistance to both innate and adaptive immune mechanisms following needle inoculation...