BB_0153

Summary

Gene Symbol: BB_0153
Description: superoxide dismutase
Species: Borrelia burgdorferi B31

Top Publications

  1. Esteve Gassent M, Elliott N, Seshu J. sodA is essential for virulence of Borrelia burgdorferi in the murine model of Lyme disease. Mol Microbiol. 2009;71:594-612 pubmed publisher
    ..These studies indicate that SodA plays an important role in combating oxidative stress and is essential for the colonization and dissemination of B. burgdorferi in the murine model of Lyme disease...
  2. Esteve Gassent M, Smith T, Small C, Thomas D, Seshu J. Absence of sodA Increases the Levels of Oxidation of Key Metabolic Determinants of Borrelia burgdorferi. PLoS ONE. 2015;10:e0136707 pubmed publisher
    ..This study, utilizing the sodA mutant, has provided insights into adaptive capabilities critical for survival of B. burgdorferi in its hosts. ..
  3. Whitehouse C, Williams L, Austin F. Identification of superoxide dismutase activity in Borrelia burgdorferi. Infect Immun. 1997;65:4865-8 pubmed
    ..None of the Lyme disease spirochetes tested possessed catalase or peroxidase activities. The borrelial SOD was not inducible by growth with increased oxygen concentrations and thus appeared to be produced constitutively...