Gene Symbol: TNF
Description: tumor necrosis factor
Alias: Cachectin, TNF-a, TNF-alpha, TNFSF2, tnfa, tumor necrosis factor, tumor necrosis factor alpha
Species: beluga whale

Top Publications

  1. Denis F, Archambault D. Molecular cloning and characterization of beluga whale (Delphinapterus leucas) interleukin-1beta and tumor necrosis factor-alpha. Can J Vet Res. 2001;65:233-40 pubmed
    Interleukin-1beta (IL-1beta) and tumor necrosis factor-alpha (TNF-alpha) are cytokines produced primarily by monocytes and macrophages with regulatory effects in inflammation and multiple aspects of the immune response...
  2. Sitt T, Bowen L, Blanchard M, Smith B, Gershwin L, Byrne B, et al. Quantitation of leukocyte gene expression in cetaceans. Dev Comp Immunol. 2008;32:1253-9 pubmed publisher
    ..Cytokine gene analysis has the potential to identify immune system perturbations induced by environmental insult as well as providing diagnostic tools for characterizing immune responses to environmental antigens and vaccines...

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