Gene Symbol: Pburs
Description: bursicon subunit beta
Alias: GB19117, sc-burs, partner of bursicon, scburs, single-chain bursicon
Species: bee

Top Publications

  1. Luo C, Dewey E, Sudo S, Ewer J, Hsu S, Honegger H, et al. Bursicon, the insect cuticle-hardening hormone, is a heterodimeric cystine knot protein that activates G protein-coupled receptor LGR2. Proc Natl Acad Sci U S A. 2005;102:2820-5 pubmed publisher
    ..first heterodimeric cystine knot hormone found in insects, consists of two proteins encoded by the genes burs and pburs (partner of burs)...
  2. Mendive F, Van Loy T, Claeysen S, Poels J, Williamson M, Hauser F, et al. Drosophila molting neurohormone bursicon is a heterodimer and the natural agonist of the orphan receptor DLGR2. FEBS Lett. 2005;579:2171-6 pubmed publisher
    ..The heterodimeric Drosophila protein displays bursicon bioactivity in freshly enclosed neck-ligated flies and is the natural agonist of the orphan G protein-coupled receptor DLGR2...
  3. Van Loy T, Van Hiel M, Vandersmissen H, Poels J, Mendive F, Vassart G, et al. Evolutionary conservation of bursicon in the animal kingdom. Gen Comp Endocrinol. 2007;153:59-63 pubmed
    ..Our results illustrate the remarkable conservation of bursicon in invertebrate species and provide an avenue for functional analyses of this hormone in a wide range of animal species. ..