Gene Symbol: spH
Description: sphingomyelinase C
Species: Bacillus anthracis str. Ames
Tomita M, Nakai K, Yamada A, Taguchi R, Ikezawa H. Secondary structure of sphingomyelinase from Bacillus cereus. J Biochem. 1990;108:811-5 pubmed
..The partial homologies between the amino acid sequences of SMPLC and Clostridium perfringens alpha-toxin (phospholipase C) are discussed. ..
Johansen T, Haugli F, Ikezawa H, Little C. Bacillus cereus strain SE-1: nucleotide sequence of the sphingomyelinase C gene. Nucleic Acids Res. 1988;16:10370 pubmed
Gavrilenko I, Baida G, Karpov A, Kuz min N. [Nucleotide sequence of phospholipase C and sphingomyelinase genes from Bacillus cereus BKM-B164]. Bioorg Khim. 1993;19:133-8 pubmed
Yamada A, Tsukagoshi N, Udaka S, Sasaki T, Makino S, Nakamura S, et al
. Nucleotide sequence and expression in Escherichia coli of the gene coding for sphingomyelinase of Bacillus cereus. Eur J Biochem. 1988;175:213-20 pubmed
..The enzymatic activity toward sphingomyelin was enhanced 20-30-fold in the presence of MgCl2, and the adsorption of the enzyme onto erythrocyte membranes was accelerated in the presence of CaCl2...
Johansen T, Holm T, Guddal P, Sletten K, Haugli F, Little C. Cloning and sequencing of the gene encoding the phosphatidylcholine-preferring phospholipase C of Bacillus cereus. Gene. 1988;65:293-304 pubmed
..coli. The cloning and sequencing described here complete the first step toward using in vitro mutagenesis for investigations of the structure-function relationships of B. cereus phospholipase C. ..
Granum P, Nissen H. Sphingomyelinase is part of the 'enterotoxin complex' produced by Bacillus cereus. FEMS Microbiol Lett. 1993;110:97-100 pubmed
Nishiwaki H, Ito K, Otsuki K, Yamamoto H, Komai K, Matsuda K. Purification and functional characterization of insecticidal sphingomyelinase C produced by Bacillus cereus. Eur J Biochem. 2004;271:601-6 pubmed