ribH

Summary

Gene Symbol: ribH
Description: 6,7-dimethyl-8-ribityllumazine synthase
Species: Bacillus subtilis subsp. subtilis str. 168

Top Publications

  1. Ludwig H, Lottspeich F, Henschen A, Ladenstein R, Bacher A. Heavy riboflavin synthase of Bacillus subtilis. Primary structure of the beta subunit. J Biol Chem. 1987;262:1016-21 pubmed
    ..The sequence shows no detectable homologies to other proteins. A computer prediction of secondary structure elements indicates 34% alpha helix and 30% beta sheet. ..
  2. Ritsert K, Huber R, Turk D, Ladenstein R, Schmidt Bäse K, Bacher A. Studies on the lumazine synthase/riboflavin synthase complex of Bacillus subtilis: crystal structure analysis of reconstituted, icosahedral beta-subunit capsids with bound substrate analogue inhibitor at 2.4 A resolution. J Mol Biol. 1995;253:151-67 pubmed
    ..A residual density feature in the final map is interpreted as a bound phosphate which mimics the binding of the second substrate. We discuss the reaction mechanism on this structural basis. ..
  3. Fischer M, Haase I, Kis K, Meining W, Ladenstein R, Cushman M, et al. Enzyme catalysis via control of activation entropy: site-directed mutagenesis of 6,7-dimethyl-8-ribityllumazine synthase. J Mol Biol. 2003;326:783-93 pubmed
    ..The ribH gene specifying the lumazine synthase subunit can be expressed in high yield...
  4. Ladenstein R, Schneider M, Huber R, Bartunik H, Wilson K, Schott K, et al. Heavy riboflavin synthase from Bacillus subtilis. Crystal structure analysis of the icosahedral beta 60 capsid at 3.3 A resolution. J Mol Biol. 1988;203:1045-70 pubmed
    ..Ligand binding at the pentamer interface regions increases the stability of the beta 60 capsid considerably and influences the reassembly of isolated beta-subunits. ..
  5. Schott K, Ladenstein R, Konig A, Bacher A. The lumazine synthase-riboflavin synthase complex of Bacillus subtilis. Crystallization of reconstituted icosahedral beta-subunit capsids. J Biol Chem. 1990;265:12686-9 pubmed
    ..A second hexagonal modification shows unit cell parameters of a = b = 156.3 and c = 622.6 A and alpha = beta = 90 degrees and gamma = 120 degrees. The space group of this modification could not be determined unambiguously. ..
  6. Graumann P, Schroder K, Schmid R, Marahiel M. Cold shock stress-induced proteins in Bacillus subtilis. J Bacteriol. 1996;178:4611-9 pubmed
  7. Gusarov I, Kreneva R, Podcharniaev D, Iomantas I, Abalakina E, Stoĭnova N, et al. [Riboflavin biosynthetic genes in Bacillus amyloliquefaciens: primary structure, organization and regulation of activity]. Mol Biol (Mosk). 1997;31:446-53 pubmed