Gene Symbol: liaG
Description: protein LiaG
Species: Bacillus subtilis subsp. subtilis str. 168
Mascher T, Zimmer S, Smith T, Helmann J. Antibiotic-inducible promoter regulated by the cell envelope stress-sensing two-component system LiaRS of Bacillus subtilis. Antimicrob Agents Chemother. 2004;48:2888-96 pubmed
..Thus, the reporter derived from P(liaI) (the liaI promoter) provides a tool for the detection and classification of antimicrobial compounds. ..
Hyyryläinen H, Sarvas M, Kontinen V. Transcriptome analysis of the secretion stress response of Bacillus subtilis. Appl Microbiol Biotechnol. 2005;67:389-96 pubmed
..B. subtilis cells respond to secretion/folding stress by various changes in gene expression, which can be seen as an attempt to combat the stress condition. ..
Cao M, Wang T, Ye R, Helmann J. Antibiotics that inhibit cell wall biosynthesis induce expression of the Bacillus subtilis sigma(W) and sigma(M) regulons. Mol Microbiol. 2002;45:1267-76 pubmed
..Our findings are consistent with the idea that one function of ECF sigma factors is to coordinate antibiosis stress responses and cell envelope homeostasis. ..
Mascher T, Margulis N, Wang T, Ye R, Helmann J. Cell wall stress responses in Bacillus subtilis: the regulatory network of the bacitracin stimulon. Mol Microbiol. 2003;50:1591-604 pubmed
..By comparing the bacitracin and the vancomycin stimulons, we can differentiate between loci induced specifically by bacitracin and those that are induced by multiple cell wall-active antibiotics. ..
Pietiäinen M, Gardemeister M, Mecklin M, Leskelä S, Sarvas M, Kontinen V. Cationic antimicrobial peptides elicit a complex stress response in Bacillus subtilis that involves ECF-type sigma factors and two-component signal transduction systems. Microbiology. 2005;151:1577-92 pubmed
..The results suggest significant overlap between different stress regulons and interdependence of signal transduction pathways mediating stress responses. ..