BBOV_II000780

Summary

Gene Symbol: BBOV_II000780
Description: dihydrofolate reductase/thymidilate synthase
Alias: 18.m06049
Species: Babesia bovis T2Bo

Top Publications

  1. Begley D, Edwards T, Raymond A, Smith E, Hartley R, Abendroth J, et al. Inhibitor-bound complexes of dihydrofolate reductase-thymidylate synthase from Babesia bovis. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2011;67:1070-7 pubmed publisher
    ..The complexes reveal modes of binding similar to that seen in drug-resistant malaria strains and point to the utility of applying structural studies with proven cancer chemotherapies towards infectious disease research. ..

Scientific Experts

Detail Information

Publications1

  1. Begley D, Edwards T, Raymond A, Smith E, Hartley R, Abendroth J, et al. Inhibitor-bound complexes of dihydrofolate reductase-thymidylate synthase from Babesia bovis. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2011;67:1070-7 pubmed publisher
    ..The complexes reveal modes of binding similar to that seen in drug-resistant malaria strains and point to the utility of applying structural studies with proven cancer chemotherapies towards infectious disease research. ..