Gene Symbol: Ac-p74
Alias: AcOrf-138, p74, occlusion-derived virus envelope protein
Species: Autographa californica nucleopolyhedrovirus
Slack J, Lawrence S, Krell P, Arif B. Trypsin cleavage of the baculovirus occlusion-derived virus attachment protein P74 is prerequisite in per os infection. J Gen Virol. 2008;89:2388-97 pubmed publisher
..Deletion of any of these factors neutralizes infectivity by the per os route. We have observed that P74 of the group I alphabaculovirus Autographa californica multiple nucleopolyhedrovirus (AcMNPV) is N-terminally ..
Wang L, Salem T, Campbell D, Turney C, Kumar C, Cheng X. Characterization of a virion occlusion-defective Autographa californica multiple nucleopolyhedrovirus mutant lacking the p26, p10 and p74 genes. J Gen Virol. 2009;90:1641-8 pubmed publisher
..multiple nucleopolyhedrovirus (AcMNPV) mutant (AcDef) that has a 2136 bp DNA deletion, including p26, p10 and p74 genes, has been isolated. No virions were detected in the polyhedra of AcDef...
Peng K, van Oers M, Hu Z, van Lent J, Vlak J. Baculovirus per os infectivity factors form a complex on the surface of occlusion-derived virus. J Virol. 2010;84:9497-504 pubmed publisher
Five highly conserved per os infectivity factors, PIF1, PIF2, PIF3, PIF4, and P74, have been reported to be essential for oral infectivity of baculovirus occlusion-derived virus (ODV) in insect larvae...
Slack J, Lawrence S, Krell P, Arif B. A soluble form of P74 can act as a per os infectivity factor to the Autographa californica multiple nucleopolyhedrovirus. J Gen Virol. 2010;91:915-8 pubmed publisher
..The Autographa californica multicapsid nucleopolyhedrovirus P74 protein is an ODV envelope protein that is essential for ODVs to be infectious...
Peng K, van Lent J, Vlak J, Hu Z, van Oers M. In situ cleavage of baculovirus occlusion-derived virus receptor binding protein P74 in the peroral infectivity complex. J Virol. 2011;85:10710-8 pubmed publisher
..The Autographa californica multicapsid nucleopolyhedrovirus (AcMNPV) occlusion-derived virus (ODV) protein P74 is part of a complex of essential peroral infectivity factors (PIFs)...