atoC

Summary

Gene Symbol: atoC
Description: fused response regulator of ato operon, in two-component system with AtoS: response regulator/sigma54 interaction protein
Alias: ECK2213, JW2214
Species:

Top Publications

  1. ncbi Identification, cloning, and nucleotide sequencing of the ornithine decarboxylase antizyme gene of Escherichia coli
    E S Canellakis
    Department of Pharmacology, Yale University School of Medicine, New Haven, CT 06510
    Proc Natl Acad Sci U S A 90:7129-33. 1993
  2. ncbi Regulation of the ato operon by the atoC gene in Escherichia coli
    L S Jenkins
    J Bacteriol 169:2096-102. 1987
  3. ncbi Genetic and molecular characterization of the genes involved in short-chain fatty acid degradation in Escherichia coli: the ato system
    L S Jenkins
    J Bacteriol 169:42-52. 1987
  4. ncbi ato Operon: a highly inducible system for acetoacetate and butyrate degradation in Escherichia coli
    G Pauli
    Eur J Biochem 29:553-62. 1972
  5. ncbi Does antizyme exist in Escherichia coli?
    I P Ivanov
    Mol Microbiol 29:1521-2. 1998
  6. ncbi Involvement of the AtoS-AtoC signal transduction system in poly-(R)-3-hydroxybutyrate biosynthesis in Escherichia coli
    Marina C Theodorou
    Laboratory of Biochemistry, Department of Chemistry, Aristotle University of Thessaloniki, Thessaloniki 54124, Greece
    Biochim Biophys Acta 1760:896-906. 2006
  7. ncbi Phosphorylation activity of the response regulator of the two-component signal transduction system AtoS-AtoC in E. coli
    Efthimia E Lioliou
    Laboratory of Biochemistry, Department of Chemistry, Aristotle University of Thessaloniki, Thessaloniki 54124, Greece
    Biochim Biophys Acta 1725:257-68. 2005
  8. ncbi Role of fadR and atoC(Con) mutations in poly(3-hydroxybutyrate-co-3-hydroxyvalerate) synthesis in recombinant pha+ Escherichia coli
    H G Rhie
    Department of Biology, Kyung Hee University, Seoul, Korea
    Appl Environ Microbiol 61:2487-92. 1995
  9. ncbi Extracellular Ca2+ transients affect poly-(R)-3-hydroxybutyrate regulation by the AtoS-AtoC system in Escherichia coli
    Marina C Theodorou
    Laboratory of Biochemistry, Department of Chemistry, Aristotle University of Thessaloniki, GR 54124 Thessaloniki, Greece
    Biochem J 417:667-72. 2009
  10. ncbi Signal transduction and adaptive regulation through bacterial two-component systems: the Escherichia coli AtoSC paradigm
    Dimitrios A Kyriakidis
    Department of Chemistry, Aristotle University of Thessaloniki, Greece
    Amino Acids 37:443-58. 2009

Scientific Experts

  • Kazuei Igarashi
  • Panagiota S Filippou
  • Dimitrios A Kyriakidis
  • Marina C Theodorou
  • Evaggelos C Theodorou
  • Christos A Panagiotidis
  • D A Kyriakidis
  • Cynthia H Panagiotidis
  • Efthimia E Lioliou
  • Ekaterini Tiligada
  • Meropi K Matta
  • A I Grigoroudis
  • Taku Oshima
  • Margarita N Samali
  • C A Panagiotidis
  • K D Kyriakidis
  • E Tiligada
  • M C Theodorou
  • M Vlassi
  • E E Lioliou
  • I P Ivanov
  • Anastasia A Pantazaki
  • Eleni P Mimitou
  • Asterios I Grigoroudis
  • Hirotada Mori
  • Masahito Sugiura
  • Takeshi Mizuno
  • Yasushi Masuda
  • Barry L Wanner
  • Hirofumi Aiba
  • Shigehiko Kanaya
  • H G Rhie
  • J F Atkins
  • R F Gesteland
  • E S Canellakis
  • D Dennis
  • L S Jenkins
  • S C Huang
  • A A Paterakis
  • W D Nunn
  • G Pauli
  • J B Stock
  • D P Clark
  • M L Rod
  • J M Mottonen
  • P Overath
  • A M Stock

Detail Information

Publications23

  1. ncbi Identification, cloning, and nucleotide sequencing of the ornithine decarboxylase antizyme gene of Escherichia coli
    E S Canellakis
    Department of Pharmacology, Yale University School of Medicine, New Haven, CT 06510
    Proc Natl Acad Sci U S A 90:7129-33. 1993
    ....
  2. ncbi Regulation of the ato operon by the atoC gene in Escherichia coli
    L S Jenkins
    J Bacteriol 169:2096-102. 1987
    ..A 48-kilodalton protein encoded by atoC was required for the synthesis or activation of the Ato enzymes...
  3. ncbi Genetic and molecular characterization of the genes involved in short-chain fatty acid degradation in Escherichia coli: the ato system
    L S Jenkins
    J Bacteriol 169:42-52. 1987
    ..A [CoA]:acetoacetyl [AA]-CoA transferase) and atoB (thiolase II), as well as mutations in the ato regulatory locus, atoC. Complementation studies performed with mutants defective in acetyl-CoA:AA-CoA transferase suggest that two loci, ..
  4. ncbi ato Operon: a highly inducible system for acetoacetate and butyrate degradation in Escherichia coli
    G Pauli
    Eur J Biochem 29:553-62. 1972
  5. ncbi Does antizyme exist in Escherichia coli?
    I P Ivanov
    Mol Microbiol 29:1521-2. 1998
  6. ncbi Involvement of the AtoS-AtoC signal transduction system in poly-(R)-3-hydroxybutyrate biosynthesis in Escherichia coli
    Marina C Theodorou
    Laboratory of Biochemistry, Department of Chemistry, Aristotle University of Thessaloniki, Thessaloniki 54124, Greece
    Biochim Biophys Acta 1760:896-906. 2006
    The AtoS-AtoC signal transduction system in E. coli, which induces the atoDAEB operon for the growth of E...
  7. ncbi Phosphorylation activity of the response regulator of the two-component signal transduction system AtoS-AtoC in E. coli
    Efthimia E Lioliou
    Laboratory of Biochemistry, Department of Chemistry, Aristotle University of Thessaloniki, Thessaloniki 54124, Greece
    Biochim Biophys Acta 1725:257-68. 2005
    Antizyme, long known to be a non-competitive inhibitor of ornithine decarboxylase, is encoded by the atoC gene in Escherichia coli...
  8. ncbi Role of fadR and atoC(Con) mutations in poly(3-hydroxybutyrate-co-3-hydroxyvalerate) synthesis in recombinant pha+ Escherichia coli
    H G Rhie
    Department of Biology, Kyung Hee University, Seoul, Korea
    Appl Environ Microbiol 61:2487-92. 1995
    Recombinant Escherichia coli fadR atoC(Con) mutants containing the polyhydroxyalkanoate (PHA) biosynthesis genes from Alcaligenes eutrophus are able to incorporate significant levels of 3-hydroxyvalerate (3HV) into the copolymer poly(3-..
  9. ncbi Extracellular Ca2+ transients affect poly-(R)-3-hydroxybutyrate regulation by the AtoS-AtoC system in Escherichia coli
    Marina C Theodorou
    Laboratory of Biochemistry, Department of Chemistry, Aristotle University of Thessaloniki, GR 54124 Thessaloniki, Greece
    Biochem J 417:667-72. 2009
    ..shows that extracellular Ca2+ controls cPHB [complexed poly-(R)-3-hydroxybutyrate] biosynthesis through the AtoS-AtoC two-component system...
  10. ncbi Signal transduction and adaptive regulation through bacterial two-component systems: the Escherichia coli AtoSC paradigm
    Dimitrios A Kyriakidis
    Department of Chemistry, Aristotle University of Thessaloniki, Greece
    Amino Acids 37:443-58. 2009
    ..In Escherichia coli, cross-talk between the AtoS histidine kinase and the AtoC response regulator, forming the AtoSC TCS, through His --> Asp phosphotransfer, activates AtoC directly to induce ..
  11. ncbi Effect of histamine on the signal transduction of the AtoS-AtoC two component system and involvement in poly-(R)-3-hydroxybutyrate biosynthesis in Escherichia coli
    D A Kyriakidis
    Laboratory of Biochemistry, Department of Chemistry, Aristotle University of Thessaloniki, Thessaloniki, Greece
    Amino Acids 35:45-52. 2008
    AtoS-AtoC two-component system acts directly on the atoDAEB operon transcription to regulate the biosynthesis of short-chain poly-(R)-3-hydroxybutyrate...
  12. ncbi Activation of the AtoSC two-component system in the absence of the AtoC N-terminal receiver domain in E. coli
    Evaggelos C Theodorou
    Laboratory of Biochemistry, Department of Chemistry, Aristotle University of Thessaloniki, 54124, Thessaloniki, Greece
    Amino Acids 40:421-30. 2011
    The AtoSC two-component system in E. coli consists of the AtoS sensor kinase and the AtoC response regulator...
  13. ncbi Interactions of the antizyme AtoC with regulatory elements of the Escherichia coli atoDAEB operon
    Meropi K Matta
    Department of Pharmaceutical Sciences, Laboratory of Biochemistry, Aristotle University, Thessaloniki 54124, Greece
    J Bacteriol 189:6324-32. 2007
    b>AtoC has a dual function as both an antizyme, the posttranslational inhibitor of polyamine biosynthetic enzymes, and the transcriptional regulator of genes involved in short-chain fatty acid catabolism (the atoDAEB operon)...
  14. ncbi Molecular modeling and functional analysis of the AtoS-AtoC two-component signal transduction system of Escherichia coli
    A I Grigoroudis
    Laboratory of Biochemistry, Department of Chemistry, Aristotle University of Thessaloniki, Thessaloniki, 54124, Greece
    Biochim Biophys Acta 1770:1248-58. 2007
    The AtoS-AtoC two-component signal transduction system positively regulates the expression of the atoDAEB operon in Escherichia coli...
  15. ncbi Spermidine triggering effect to the signal transduction through the AtoS-AtoC/Az two-component system in Escherichia coli
    Marina C Theodorou
    Laboratory of Biochemistry, Department of Chemistry, Aristotle University of Thessaloniki, Thessaloniki, 54124, Greece
    Biochim Biophys Acta 1770:1104-14. 2007
    Recent analysis revealed that, in Escherichia coli the AtoS-AtoC/Az two-component system (TCS) and its target atoDAEB operon regulate the biosynthesis of short-chain poly-(R)-3-hydroxybutyrate (cPHB) biosynthesis, a biopolymer with many ..
  16. ncbi Effect of polyamines and synthetic polyamine-analogues on the expression of antizyme (AtoC) and its regulatory genes
    Panagiota S Filippou
    Laboratory of Biochemistry, Department of Chemistry, Aristotle University of Thessaloniki, Thessaloniki, 54124, Greece
    BMC Biochem 8:1. 2007
    ..coli. Az was also revealed to be the product of the atoC gene...
  17. ncbi [Physiological functions of polyamines and regulation of polyamine content in cells]
    Kazuei Igarashi
    Graduate School of Pharmaceutical Sciences, Chiba University, Inohana, Japan
    Yakugaku Zasshi 126:455-71. 2006
    ..Increased levels of polyamine oxidase and acrolein are good markers of chronic renal failure and brain stroke...
  18. ncbi Signal transduction in bacteria
    J B Stock
    Department of Molecular Biology, Princeton University, New Jersey 08544
    Nature 344:395-400. 1990
    ..This phosphotransfer network couples environmental signals to an array of response elements that control cell motility and regulate gene expression...
  19. ncbi Regulatory mutations that allow the growth of Escherichia coli on butanol as carbon source
    D P Clark
    Department of Microbiology, Southern Illinois University, Carbondale 62901
    J Mol Evol 25:151-8. 1987
    ..When the adhR mutation expressing the highest ADH and ACDH levels was present together with fadR and atoC mutations (allowing efficient catabolism of acetoacetyl-CoA) and with an aceX mutation, the resulting strains ..
  20. ncbi AtoSC two-component system is involved in cPHB biosynthesis through fatty acid metabolism in E. coli
    Evaggelos C Theodorou
    Department of Chemistry, Aristotle University of Thessaloniki, Thessaloniki, Greece
    Biochim Biophys Acta 1810:561-8. 2011
    ..We have shown previously that AtoSC two-component system regulates the biosynthesis of E. coli cPHB [complexed poly-(R)-3-hydroxybutyrate]...
  21. ncbi Transcriptome analysis of all two-component regulatory system mutants of Escherichia coli K-12
    Taku Oshima
    Research and Education Center for Genetic Information, Nara Institute of Science and Technology, Ikoma 630 0101, Japan
    Mol Microbiol 46:281-91. 2002
    ..The compiled data are avail-able at our website (http://ecoli.aist-nara.ac.jp/xp_analysis/ 2_components)...