Research Topics

Genomes and Genes



Gene Symbol: dnaK
Description: DNAK Protein
Alias: AGR_C_195
Species: Agrobacterium tumefaciens str. C58

Top Publications

  1. Segal G, Ron E. The dnaKJ operon of Agrobacterium tumefaciens: transcriptional analysis and evidence for a new heat shock promoter. J Bacteriol. 1995;177:5952-8 pubmed
    ..There were two transcripts representing the dnaKJ operon: one containing the dnaK and dnaJ genes and the second containing only the dnaK gene...
  2. Boshoff A, Hennessy F, Blatch G. The in vivo and in vitro characterization of DnaK from Agrobacterium tumefaciens RUOR. Protein Expr Purif. 2004;38:161-9 pubmed
    Molecular chaperones of the heat shock protein 70 family (Hsp70; also called DnaK in prokaryotes) play an important role in the folding and functioning of cellular protein machinery...
  3. Eardly B, Nour S, van Berkum P, Selander R. Rhizobial 16S rRNA and dnaK genes: mosaicism and the uncertain phylogenetic placement of Rhizobium galegae. Appl Environ Microbiol. 2005;71:1328-35 pubmed
    ..among 12 agriculturally important species in the order Rhizobiales was estimated by comparative 16S rRNA and dnaK sequence analyses. Two groups of related species were identified by neighbor-joining and maximum-parsimony analysis...
  4. Boshoff A, Stephens L, Blatch G. The Agrobacterium tumefaciens DnaK: ATPase cycle, oligomeric state and chaperone properties. Int J Biochem Cell Biol. 2008;40:804-12 pubmed
    b>DnaK is a molecular chaperone that promotes cell survival during stress by preventing protein misfolding...
  5. Hennessy F, Boshoff A, Blatch G. Rational mutagenesis of a 40 kDa heat shock protein from Agrobacterium tumefaciens identifies amino acid residues critical to its in vivo function. Int J Biochem Cell Biol. 2005;37:177-91 pubmed publisher
    Prokaryotic DnaJ and DnaK, homologous to the eukaryotic 40 and 70kDa heat shock proteins (Hsp40 and Hsp70) respectively, play an important role as molecular chaperones in assisted protein folding under both normal and stressed conditions...