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| catRSummaryGene Symbol: catR Description: catalase R catR-Aspergillus niger Species: Publications The essential function of the small Tim proteins in the TIM22 import pathway does not depend on formation of the soluble 70-kilodalton complexM P Murphy MRC Dunn Human Nutrition Unit, MRC Wellcome, Cambridge CB2 2XY, United Kingdom Mol Cell Biol 21:6132-8 Suppressors of the temperature sensitivity of DNA polymerase alpha mutations in Saccharomyces cerevisiaeT Formosa Department of Biochemistry, University of Utah School of Medicine, Salt Lake City 84132, USA Mol Gen Genet 257:461-8 Sec3p is a spatial landmark for polarized secretion in budding yeastF P Finger Department of Cell Biology, Yale University School of Medicine, New Haven, Connecticut 06520 8002, USA Cell 92:559-71 Isolation, characterization, and molecular cloning of a protein (Abp2) that binds to a Schizosaccharomyces pombe origin of replication (ars3002)J P Sanchez Graduate Program in Molecular Biology, Memorial Sloan Kettering Cancer Center, New York, New York 10021, USA Mol Cell Biol 18:1670-81 Characterization and heterologous expression of hydroxycinnamoyl/benzoyl-CoA:anthranilate N-hydroxycinnamoyl/benzoyltransferase from elicited cell cultures of carnation, Dianthus caryophyllus LQ Yang Institut für Biologie II, Lehrstuhl für Biochemie der Pflanzen, Universität Freiburg, Germany Plant Mol Biol 35:777-89 RDH54, a RAD54 homologue in Saccharomyces cerevisiae, is required for mitotic diploid-specific recombination and repair and for meiosisH L Klein Department of Biochemistry and Kaplan Cancer Center, New York University Medical Center, New York 10016, USA Genetics 147:1533-43 Effect of temperature on the role of Hsp104 and trehalose in barotolerance of Saccharomyces cerevisiaeH Iwahashi National Institute of Bioscience and Human Technology, Tsukuba, Ibaraki, Japan FEBS Lett 416:1-5 Saccharomyces cerevisiae basic region-leucine zipper protein regulatory networks converge at the ATR1 structural geneS T Coleman Department of Physiology and Biophysics, University of Iowa, Iowa City, Iowa 52242, USA J Biol Chem 272:23224-30 A large protein complex containing the yeast Sin3p and Rpd3p transcriptional regulatorsM M Kasten Department of Oncological Sciences, Huntsman Cancer Institute, University of Utah Health Sciences Center, Salt Lake City 84132, USA Mol Cell Biol 17:4852-8 Two classes of human papillomavirus type 16 E1 mutants suggest pleiotropic conformational constraints affecting E1 multimerization, E2 interaction, and interaction with cellular proteinsT Yasugi ol>Department of Pathology, Harvard Medical School, Boston, Massachusetts 02115, USA J Virol 71:5942-51 | Scientific Experts
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Detail Information
Publications
The essential function of the small Tim proteins in the TIM22 import pathway does not depend on formation of the soluble 70-kilodalton complexM P Murphy
MRC Dunn Human Nutrition Unit, MRC Wellcome, Cambridge CB2 2XY, United Kingdom
Mol Cell Biol 21:6132-8
MRC Dunn Human Nutrition Unit, MRC Wellcome, Cambridge CB2 2XY, United Kingdom
Mol Cell Biol 21:6132-8
....
Suppressors of the temperature sensitivity of DNA polymerase alpha mutations in Saccharomyces cerevisiaeT Formosa
Department of Biochemistry, University of Utah School of Medicine, Salt Lake City 84132, USA
Mol Gen Genet 257:461-8
Department of Biochemistry, University of Utah School of Medicine, Salt Lake City 84132, USA
Mol Gen Genet 257:461-8
..We also describe a transposon-mediated strategy that should be generally effective for rapid characterization of multicopy suppressors...
Sec3p is a spatial landmark for polarized secretion in budding yeastF P Finger
Department of Cell Biology, Yale University School of Medicine, New Haven, Connecticut 06520 8002, USA
Cell 92:559-71
Department of Cell Biology, Yale University School of Medicine, New Haven, Connecticut 06520 8002, USA
Cell 92:559-71
..We propose that Sec3p is a spatial landmark defining sites of exocytosis. Polarized secretion would result from the coupling of actin-dependent vesicle targeting with Sec3p-dependent establishment of the vesicle fusion site...
Isolation, characterization, and molecular cloning of a protein (Abp2) that binds to a Schizosaccharomyces pombe origin of replication (ars3002)J P Sanchez
Graduate Program in Molecular Biology, Memorial Sloan Kettering Cancer Center, New York, New York 10021, USA
Mol Cell Biol 18:1670-81
Graduate Program in Molecular Biology, Memorial Sloan Kettering Cancer Center, New York, New York 10021, USA
Mol Cell Biol 18:1670-81
..The null mutant was also sensitive to UV radiation, suggesting that Abp2 may play a role in regulating the cell cycle response to stress signals...
Characterization and heterologous expression of hydroxycinnamoyl/benzoyl-CoA:anthranilate N-hydroxycinnamoyl/benzoyltransferase from elicited cell cultures of carnation, Dianthus caryophyllus LQ Yang
Institut für Biologie II, Lehrstuhl für Biochemie der Pflanzen, Universität Freiburg, Germany
Plant Mol Biol 35:777-89
Institut für Biologie II, Lehrstuhl für Biochemie der Pflanzen, Universität Freiburg, Germany
Plant Mol Biol 35:777-89
..Thus the cDNAs described represent also the first hydroxycinnamoyl-transferases cloned from plants, which classifies the enzymes as hydroxycinnamoyl/benzoyltransferases...
RDH54, a RAD54 homologue in Saccharomyces cerevisiae, is required for mitotic diploid-specific recombination and repair and for meiosisH L Klein
Department of Biochemistry and Kaplan Cancer Center, New York University Medical Center, New York 10016, USA
Genetics 147:1533-43
Department of Biochemistry and Kaplan Cancer Center, New York University Medical Center, New York 10016, USA
Genetics 147:1533-43
..The RDH54 gene is also required for meiosis as homozygous mutant diploids show very poor sporulation and reduced spore viability. The role of the RDH54 gene in mitotic repair and in meiosis and the pathway in which it acts are discussed...
Effect of temperature on the role of Hsp104 and trehalose in barotolerance of Saccharomyces cerevisiaeH Iwahashi
National Institute of Bioscience and Human Technology, Tsukuba, Ibaraki, Japan
FEBS Lett 416:1-5
National Institute of Bioscience and Human Technology, Tsukuba, Ibaraki, Japan
FEBS Lett 416:1-5
..These results suggest that the role of Hsp104 in barotolerance is temperature dependent in contrast to trehalose...
Saccharomyces cerevisiae basic region-leucine zipper protein regulatory networks converge at the ATR1 structural geneS T Coleman
Department of Physiology and Biophysics, University of Iowa, Iowa City, Iowa 52242, USA
J Biol Chem 272:23224-30
Department of Physiology and Biophysics, University of Iowa, Iowa City, Iowa 52242, USA
J Biol Chem 272:23224-30
..These data provide the first indication of overlap between the regulatory networks defined by yAP-1 and Gcn4p...
A large protein complex containing the yeast Sin3p and Rpd3p transcriptional regulatorsM M Kasten
Department of Oncological Sciences, Huntsman Cancer Institute, University of Utah Health Sciences Center, Salt Lake City 84132, USA
Mol Cell Biol 17:4852-8
Department of Oncological Sciences, Huntsman Cancer Institute, University of Utah Health Sciences Center, Salt Lake City 84132, USA
Mol Cell Biol 17:4852-8
..We show that Rpd3p is present in the Sin3p complex and that an rpd3 mutation eliminates SIN3-dependent repression. Thus, Sin3p may function as a bridge to recruit the Rpd3p histone deacetylase to specific promoters...
Two classes of human papillomavirus type 16 E1 mutants suggest pleiotropic conformational constraints affecting E1 multimerization, E2 interaction, and interaction with cellular proteinsT Yasugi
Department of Pathology, Harvard Medical School, Boston, Massachusetts 02115, USA
J Virol 71:5942-51
Department of Pathology, Harvard Medical School, Boston, Massachusetts 02115, USA
J Virol 71:5942-51
..This suggests that E1 proteins are not modular but may instead be composed of multiple structurally and/or functionally interdependent domains...
The two isoenzymes for yeast NAD+-dependent glycerol 3-phosphate dehydrogenase encoded by GPD1 and GPD2 have distinct roles in osmoadaptation and redox regulationR Ansell
Department of General and Marine Microbiology, Gothenburg University, Sweden
EMBO J 16:2179-87
Department of General and Marine Microbiology, Gothenburg University, Sweden
EMBO J 16:2179-87
..We conclude that expression of GPD2 is controlled by a novel, oxygen-independent, signalling pathway which is required to regulate metabolism under anoxic conditions...
The yeast ORF YDL202w codes for the mitochondrial ribosomal protein YmL11D M Bui
Vienna Biocenter, Institute of Microbiology and Genetics, University of Vienna, A 1030 Wien, Austria
Curr Genet 31:396-400
Vienna Biocenter, Institute of Microbiology and Genetics, University of Vienna, A 1030 Wien, Austria
Curr Genet 31:396-400
..A mitochondrial location of the YDL202w gene product was proven by use of a carboxy terminally HA-tagged version. These findings clearly indicate that YDL202w encodes this mitochondrial ribosomal protein (YmL11)...
p-Cymene catabolic pathway in Pseudomonas putida F1: cloning and characterization of DNA encoding conversion of p-cymene to p-cumateR W Eaton
National Health and Environmental Effects Research Laboratory, U S Environmental Protection Agency, Gulf Breeze, Florida 32561, USA
J Bacteriol 179:3171-80
National Health and Environmental Effects Research Laboratory, U S Environmental Protection Agency, Gulf Breeze, Florida 32561, USA
J Bacteriol 179:3171-80
..putida F1...
Isoforms of ankyrin-3 that lack the NH2-terminal repeats associate with mouse macrophage lysosomesT C Hoock
Division of Hematology Oncology, Children s Hospital and the Dana Farber Cancer Institute, Boston, Massachusetts 02115, USA
J Cell Biol 136:1059-70
Division of Hematology Oncology, Children s Hospital and the Dana Farber Cancer Institute, Boston, Massachusetts 02115, USA
J Cell Biol 136:1059-70
..This is the first evidence for the association of an ankyrin with lysosomes and is an example of two ankyrins present in the same cell that segregate to different locations...
Poly(A) tail length control in Saccharomyces cerevisiae occurs by message-specific deadenylationC E Brown
Department of Molecular and Cell Biology, University of California at Berkeley, Berkeley, California 94720, USA
Mol Cell Biol 18:6548-59
Department of Molecular and Cell Biology, University of California at Berkeley, Berkeley, California 94720, USA
Mol Cell Biol 18:6548-59
..The ability to control the length of the poly(A) tail for newly expressed mRNAs has the potential to be an important posttranscriptional regulatory step in gene expression...
ATP-dependent chromatin remodelling: SWI/SNF and Co. are on the jobC Muchardt
Unite des Virus Oncogenes URA1644 du CNRS Departement des Biotechnologies, Institut Pasteur, Paris, France
J Mol Biol 293:187-98
Unite des Virus Oncogenes URA1644 du CNRS Departement des Biotechnologies, Institut Pasteur, Paris, France
J Mol Biol 293:187-98
..Although all cellular genes may not depend on chromatin remodelling for normal expression, recent data has shown that the complexes are required for both positive and negative control of a variety of cellular pathways...
Functional reconstitution of the import of the yeast ADP/ATP carrier mediated by the TIM10 complexP Luciano
School of Biological Sciences, 2 205 Stopford Building, University of Manchester, Oxford Road, Manchester M13 9PT, UK
EMBO J 20:4099-106
School of Biological Sciences, 2 205 Stopford Building, University of Manchester, Oxford Road, Manchester M13 9PT, UK
EMBO J 20:4099-106
..We conclude that the TIM10 complex can be formed exclusively from Tim9 and Tim10 and that the reconstituted complex efficiently restores AAC import in a strain lacking the TIM10 complex...
Reconstitution of Epstein-Barr virus-based plasmid partitioning in budding yeastP Kapoor
Department of Medical Genetics and Microbiology, University of Toronto, 1 Kings College Circle, Toronto, Canada M5S 1A8
EMBO J 20:222-30
Department of Medical Genetics and Microbiology, University of Toronto, 1 Kings College Circle, Toronto, Canada M5S 1A8
EMBO J 20:222-30
..The results provide direct evidence of the role of hEBP2 in EBNA1-mediated segregation and demonstrate that heterologous segregation systems can be reconstituted in yeast...
Intragenic complementation and the structure and function of argininosuccinate lyaseB Yu
Department of Biochemistry, Faculty of Medicine, University of Toronto, Ontario, Canada
Cell Mol Life Sci 57:1637-51
Department of Biochemistry, Faculty of Medicine, University of Toronto, Ontario, Canada
Cell Mol Life Sci 57:1637-51
..This review describes the structure and function of ASL and its homologue delta crystallin, the genetic defects associated with argininosuccinic aciduria and current theories regarding complementation in this protein...
The endoribonuclease activity of mammalian IRE1 autoregulates its mRNA and is required for the unfolded protein responseW Tirasophon
Department of Biological Chemistry, University of Michigan Medical Center, Ann Arbor, Michigan 48109 0650, USA
Genes Dev 14:2725-36
Department of Biological Chemistry, University of Michigan Medical Center, Ann Arbor, Michigan 48109 0650, USA
Genes Dev 14:2725-36
..Finally, the RNase activity of wild-type IRE1 alpha down-regulates hIre1 alpha mRNA expression by a novel mechanism involving cis-mediated IRE1 alpha-dependent cleavage at three specific sites within the 5' end of Ire1 alpha mRNA...
Characterization and expression of monosaccharide transporters (osMSTs) in riceK Toyofuku
Bioscience Center and Graduate School of Bioagricultural Sciences, Nagoya University, Chikusa, Japan
Plant Cell Physiol 41:940-7
Bioscience Center and Graduate School of Bioagricultural Sciences, Nagoya University, Chikusa, Japan
Plant Cell Physiol 41:940-7
..These results suggested that OsMST3 is involved in the accumulation of monosaccharides required for cell wall synthesis at the stage of cell thickening...
Expression of the Krüppel-like zinc finger gene biklf during zebrafish developmentA Kawahara
Laboratory of Molecular Genetics, National Institute of Child Health and Human Development, National Institutes of Health, MD 20892, Bethesda, USA
Mech Dev 97:173-6
Laboratory of Molecular Genetics, National Institute of Child Health and Human Development, National Institutes of Health, MD 20892, Bethesda, USA
Mech Dev 97:173-6
..Blood island staining of biklf continues through somitogenesis as the most prominent area of biklf expression...
Co-repressor complexes and remodelling chromatin for repressionA P Wolffe
Laboratory of Molecular Embryology, National Institute of Child Heath and Human Development, NIH, Building 18T, Room 106, Bethesda, MD 20892 5431, USA
Biochem Soc Trans 28:379-86
Laboratory of Molecular Embryology, National Institute of Child Heath and Human Development, NIH, Building 18T, Room 106, Bethesda, MD 20892 5431, USA
Biochem Soc Trans 28:379-86
..Remarkably, both of these complexes also contain methyl-CpG-binding proteins. This observation provides a molecular mechanism to integrate DNA methylation fully into gene control in vertebrates...
Interactions of Cdk7 and Kin28 with Hint/PKCI-1 and Hnt1 histidine triad proteinsN Korsisaari
Haartman Institute and Biocentrum Helsinki, P O Box 21, University of Helsinki, 00014 Helsinki, Finland
J Biol Chem 275:34837-40
Haartman Institute and Biocentrum Helsinki, P O Box 21, University of Helsinki, 00014 Helsinki, Finland
J Biol Chem 275:34837-40
..The physical and genetic interactions of Hint and Hnt1 with Cdk7 and Kin28 suggest a role for this class of histidine triad proteins in the regulation of Cdk7 and Kin28 functions...
Promoter targeting and chromatin remodeling by the SWI/SNF complexC L Peterson
Department of Biochemistry and Molecular Biology, Program in Molecular Medicine, University of Massachusetts Medical School, Worcester, 01605, USA
Curr Opin Genet Dev 10:187-92
Department of Biochemistry and Molecular Biology, Program in Molecular Medicine, University of Massachusetts Medical School, Worcester, 01605, USA
Curr Opin Genet Dev 10:187-92
....
A yeast taf17 mutant requires the Swi6 transcriptional activator for viability and shows defects in cell cycle-regulated transcriptionN Macpherson
Department of Molecular and Medical Genetics, University of Toronto, Toronto, Ontario M55 1A8, Canada
Genetics 154:1561-76
Department of Molecular and Medical Genetics, University of Toronto, Toronto, Ontario M55 1A8, Canada
Genetics 154:1561-76
..The cell cycle and transcriptional defects caused by taf17(slm7-1) are consistent with the role of TAF(II)s as modulators of transcriptional activation and may reflect a role for TAF17 in regulating activation by SBF and MBF...
Functional conservation of RNA polymerase II in fission and budding yeastsG V Shpakovski
Service de Biochimie and Génétique Moléculaire, CEA Saclay, Bât 142, F 91191, France
J Mol Biol 295:1119-27
Service de Biochimie and Génétique Moléculaire, CEA Saclay, Bât 142, F 91191, France
J Mol Biol 295:1119-27
..In the case of Rpb3, growth was restored by increasing the gene dosage of the host Rpb11 or Rpb10 subunits, confirming previous evidence of a close genetic interaction between these three subunits...
SAC1 encodes a regulated lipid phosphoinositide phosphatase, defects in which can be suppressed by the homologous Inp52p and Inp53p phosphatasesW E Hughes
Protein Phosphorylation, Imperial Cancer Research Fund, 44 Lincoln s Inn Fields, London WC2A 3PX, United Kingdom
J Biol Chem 275:801-8
Protein Phosphorylation, Imperial Cancer Research Fund, 44 Lincoln s Inn Fields, London WC2A 3PX, United Kingdom
J Biol Chem 275:801-8
..It is concluded that SAC1 encodes a novel lipid phosphoinositide phosphatase in which specific mutations can cause the sac1 phenotypes by altering the in vivo regulation of the protein rather than by destroying phosphatase activity...
Characterization of a high mobility group 1/2 homolog in yeastJ Lu
Department of Molecular Biology and Biochemistry, Center for Advanced Biotechnology and Medicine, Rutgers University, Piscataway, New Jersey 08855, USA
J Biol Chem 271:33678-85
Department of Molecular Biology and Biochemistry, Center for Advanced Biotechnology and Medicine, Rutgers University, Piscataway, New Jersey 08855, USA
J Biol Chem 271:33678-85
..Taken together, the data indicate that HMO1 is likely to be the homolog of HMG1/2 in higher cells and that it plays an important role in genome maintenance...
Human glycogen debranching enzyme gene (AGL): complete structural organization and characterization of the 5' flanking regionY Bao
Department of Pediatrics, Duke University Medical Center, Durham, North Carolina 27710, USA
Genomics 38:155-65
Department of Pediatrics, Duke University Medical Center, Durham, North Carolina 27710, USA
Genomics 38:155-65
..These results suggest that the human AGL gene contains at least 2 promoter regions that confer differential expression of isoform mRNAs in a tissue-specific manner...
Human RNaseP RNA and nucleolar 7-2 RNA share conserved 'To' antigen-binding domainsM H Liu
Department of Pharmacology, Baylor College of Medicine, Houston, Texas 77030
Mol Cell Biochem 130:75-82
Department of Pharmacology, Baylor College of Medicine, Houston, Texas 77030
Mol Cell Biochem 130:75-82
..These data are supportive of the idea that these two RNAs may have evolved from a common progenitor molecule...
Cloning and characterization of GPD2, a second gene encoding sn-glycerol 3-phosphate dehydrogenase (NAD+) in Saccharomyces cerevisiae, and its comparison with GPD1P Eriksson
Department of General and Marine Microbiology, University of Göteborg, Sweden
Mol Microbiol 17:95-107
Department of General and Marine Microbiology, University of Göteborg, Sweden
Mol Microbiol 17:95-107
..4 m nacl...
Thiamin pyrophosphokinase: structure, properties, and role in thiamin metabolismA I Voskoboyev
Ann N Y Acad Sci 378:161-76
Ann N Y Acad Sci 378:161-76
The isolation and characterization of a hydroxamic acid (aerobactin) formed by Aerobacter aerogenes 62-IF Gibson
Biochim Biophys Acta 192:175-84
Biochim Biophys Acta 192:175-84
Purification and properties of agmatine ureohydrolyase, a putrescine biosynthetic enzyme in Escherichia coliC Satishchandran
J Bacteriol 165:843-8
J Bacteriol 165:843-8
..Ornithine inhibited AUH activity noncompetitively (Ki = 6 X 10(-3) M), while arginine inhibited AUH activity competitively (Ki = 9 X 10(-3) M)...
Cloning and characterization of the gene for the yeast cytoplasmic threonyl-tRNA synthetaseL K Pape
Nucleic Acids Res 13:6171-83
Nucleic Acids Res 13:6171-83
..In situ disruption of the chromosomal copy of THS1 is lethal to the cell, indicating that this gene codes for the cytoplasmic threonyl-tRNA synthetase...
Structure of the Saccharomyces cerevisiae URA4 gene encoding dihydroorotaseA Guyonvarch
Laboratoire de Génetique Physiologique, IBMC du CNRS, Strasbourg, France
Mol Gen Genet 212:134-41
Laboratoire de Génetique Physiologique, IBMC du CNRS, Strasbourg, France
Mol Gen Genet 212:134-41
..S. cerevisiae dihydroorotase shows 40% homology with the S. typhimurium and E. coli enzymes and 23% homology with the D. melanogaster enzyme. A potential active site has been predicted for dihydroorotase from these comparisons...
Molecular cloning of cDNA for antimycin A-inducible mRNA and its role in cyanide-resistant respiration in Hansenula anomalaS Sakajo
Department of Biochemistry, Niigata College of Pharmacy, Japan
Biochim Biophys Acta 1090:102-8
Department of Biochemistry, Niigata College of Pharmacy, Japan
Biochim Biophys Acta 1090:102-8
..It is suggested that the cloned cDNA encodes a protein involved in the cyanide-resistant respiratory pathway...
The urea amidolyase (DUR1,2) gene of Saccharomyces cerevisiaeF S Genbauffe
Department of Microbiology and Immunology, University of Tennessee, Memphis 38163
DNA Seq 2:19-32
Department of Microbiology and Immunology, University of Tennessee, Memphis 38163
DNA Seq 2:19-32
..The termini of minor protection fragments also occur at eleven other positions as well...
Pleiotropic control of Listeria monocytogenes virulence factors by a gene that is autoregulatedJ Mengaud
Unité de Génie Microbiologique, Institut Pasteur, Paris, France
Mol Microbiol 5:2273-83
Unité de Génie Microbiologique, Institut Pasteur, Paris, France
Mol Microbiol 5:2273-83
..In late-exponential growth and at the beginning of the stationary phase, prfA transcripts of 1 kb are predominantly detected. Our results demonstrate that since prfA controls plcA transcription, it also regulates its own synthesis...
RPC10 encodes a new mini subunit shared by yeast nuclear RNA polymerasesI Treich
DBCM, Section of Biochemistry and Molecular Genetics, Saclay Research Center, Gif sur Yvette, France
Gene Expr 2:31-7
DBCM, Section of Biochemistry and Molecular Genetics, Saclay Research Center, Gif sur Yvette, France
Gene Expr 2:31-7
..Deletion of its gene indicated that, despite its very small size, the ABC10 alpha subunit is essential for yeast cell viability. ABC10 alpha and ABC10 beta have little sequence similarity...
CoA-dependent methylmalonate-semialdehyde dehydrogenase, a unique member of the aldehyde dehydrogenase superfamily. cDNA cloning, evolutionary relationships, and tissue distributionN Y Kedishvili
Department of Biochemistry and Molecular Biology, Indiana University School of Medicine, Indianapolis 46202 5122
J Biol Chem 267:19724-9
Department of Biochemistry and Molecular Biology, Indiana University School of Medicine, Indianapolis 46202 5122
J Biol Chem 267:19724-9
..MMSDH clearly belongs to a superfamily of aldehyde dehydrogenases and is closely related to betaine aldehyde dehydrogenase, 2-hydroxymuconic semialdehyde dehydrogenase, and class 1 and 2 aldehyde dehydrogenases...
Sequence analysis of sarcosine oxidase and nearby genes reveals homologies with key enzymes of folate one-carbon metabolismL J Chlumsky
Department of Biological Chemistry, Hahnemann University School of Medicine, Philadelphia, Pennsylvania 19102, USA
J Biol Chem 270:18252-9
Department of Biological Chemistry, Hahnemann University School of Medicine, Philadelphia, Pennsylvania 19102, USA
J Biol Chem 270:18252-9
..The results suggest that the alpha subunit and dimethylglycine dehydrogenase contain an NH2-terminal domain that binds noncovalent or covalent FAD, respectively, and a carboxyl-terminal H4folate-binding domain...
A pre-induction sporulation gene from Aspergillus nidulansC Lewis
Waksman Institute, Rutgers University, Piscataway, New Jersey 08854, USA
Microbiology 141:1821-8
Waksman Institute, Rutgers University, Piscataway, New Jersey 08854, USA
Microbiology 141:1821-8
..Hybridization of acoB DNA with DNA from a variety of Aspergillus species showed that homology to this gene is largely restricted to sexually sporulating species that belong to the nidulans group...
A novel DNA-binding domain that may form a single zinc finger motifS Yanagisawa
Department of Life Sciences Chemistry, Graduate School of Arts and Sciences, University of Tokyo, Japan
Nucleic Acids Res 23:3403-10
Department of Life Sciences Chemistry, Graduate School of Arts and Sciences, University of Tokyo, Japan
Nucleic Acids Res 23:3403-10
..In addition, Southern blot analysis and a survey of DNA databases suggested that proteins that include Dof domains might exist in other eukaryotes, at least in the plant kingdom...
A novel 66-kilodalton protein complexes with Rrn6, Rrn7, and TATA-binding protein to promote polymerase I transcription initiation in Saccharomyces cerevisiaeC W Lin
Basic Sciences Division, Hutchinson Cancer Research Center, Seattle, Washington 98109, USA
Mol Cell Biol 16:6436-43
Basic Sciences Division, Hutchinson Cancer Research Center, Seattle, Washington 98109, USA
Mol Cell Biol 16:6436-43
..This assay also verified the previously described strong association between Rrn6 and Rrn7, independent of the Rrn6 leucine repeat...
The cloning and sequencing of the alcB gene, coding for alcohol dehydrogenase II, in Aspergillus nidulansG D Hunter
Department of Applied Biology, University of Hull, UK
Curr Genet 29:122-9
Department of Applied Biology, University of Hull, UK
Curr Genet 29:122-9
..nidulans than to the ADHs of S. pombe and S. cerevisiae. The significance of consensus sequences found in the 5' region of the gene is discussed in relation to the regulation of the gene...
Improved radiolabeled substrates for soluble epoxide hydrolaseB Borhan
Department of Chemistry, University of California, Davis 95616, USA
Anal Biochem 231:188-200
Department of Chemistry, University of California, Davis 95616, USA
Anal Biochem 231:188-200
..Mouse sEH hydrates [(3)H]-tDPPO at 26,200 nmol/min/mg protein, and a K(m)p4 of 2.80 microM is observed...
The yeast ZRT1 gene encodes the zinc transporter protein of a high-affinity uptake system induced by zinc limitationH Zhao
Department of Biochemistry and Molecular Biology, School of Medicine, University of Minnesota, Duluth 55812, USA
Proc Natl Acad Sci U S A 93:2454-8
Department of Biochemistry and Molecular Biology, School of Medicine, University of Minnesota, Duluth 55812, USA
Proc Natl Acad Sci U S A 93:2454-8
..These results suggest that ZRT1 is regulated at the transcriptional level by the intracellular concentration of zinc. ZRT1 is an additional member of a growing family of metal transport proteins...
Cloning and sequence analysis of cDNA for a possible DNA-binding protein 5E5 in the nervous systemE Suzuki
Department of Molecular Physiology, National Institute for Physiological Sciences, Aichi
J Biochem 118:122-8
Department of Molecular Physiology, National Institute for Physiological Sciences, Aichi
J Biochem 118:122-8
..Transfection studies indicated that 5E5 protein expressed in COS-1 is localized in cell nuclei. These results suggest that 5E5 protein is a possible DNA-binding protein which is expressed especially in neurons...
A mammalian DNA-binding protein that contains a chromodomain and an SNF2/SWI2-like helicase domainV Delmas
Institute for Cancer Research, Fox Chase Cancer Center, Philadelphia, PA 19111
Proc Natl Acad Sci U S A 90:2414-8
Institute for Cancer Research, Fox Chase Cancer Center, Philadelphia, PA 19111
Proc Natl Acad Sci U S A 90:2414-8
..Based on its interesting combination of features, we suspect that CHD-1 plays an important role in gene regulation...
dUTP pyrophosphatase is an essential enzyme in Saccharomyces cerevisiaeM H Gadsden
Department of Biology, York University, Toronto, Ontario, Canada
EMBO J 12:4425-31
Department of Biology, York University, Toronto, Ontario, Canada
EMBO J 12:4425-31
..These results are in general agreement with previous models in thymine-less death that implicate dUTP metabolism. They also suggest an alternative approach for chemotherapeutic drug design...
Inactivation properties of voltage-gated K+ channels altered by presence of beta-subunitJ Rettig
Zentrum für Molekulare Neurobiologie Hamburg, Institut für Neurale Signalverarbeitung, Germany
Nature 369:289-94
Zentrum für Molekulare Neurobiologie Hamburg, Institut für Neurale Signalverarbeitung, Germany
Nature 369:289-94
..This effect is mediated by an inactivating ball domain in the Kv beta 1 amino terminus...
Cloning and nucleotide sequence of cDNA encoding Asp-hemolysin from Aspergillus fumigatusK Ebina
Department of Hygienic Chemistry, Tohoku College of Pharmacy, Sendai, Japan
Biochim Biophys Acta 1219:148-50
Department of Hygienic Chemistry, Tohoku College of Pharmacy, Sendai, Japan
Biochim Biophys Acta 1219:148-50
..A potential signal sequence was also identified in the N-terminal domain of the deduced amino acid sequence...
Primary structure and biological features of a thermostable nuclease isolated from Staphylococcus hyicusO Chesneau
National Reference Center for Staphylococci, Laboratoire des Staphylocoques et des Streptocoques, Institut Pasteur, Paris, France
Gene 145:41-7
National Reference Center for Staphylococci, Laboratoire des Staphylocoques et des Streptocoques, Institut Pasteur, Paris, France
Gene 145:41-7
..Moreover, activity was retained after heating at 100 degrees C, suggesting that the enzyme could undergo reversible unfolding...
Identification and functional analysis of a developmentally regulated extracellular signal-regulated kinase gene in Dictyostelium discoideumC Gaskins
Department of Biology, University of California, San Diego, La Jolla 92093 0634
Mol Cell Biol 14:6996-7012
Department of Biology, University of California, San Diego, La Jolla 92093 0634
Mol Cell Biol 14:6996-7012
..Our results indicate that ERK1 plays an essential role during the growth and differentiation of D. discoideum...
MluI site-dependent transcriptional regulation of the Candida albicans dUTPase geneE M McIntosh
Department of Biology, University of York, Toronto, Ontario, Canada
Curr Genet 26:415-21
Department of Biology, University of York, Toronto, Ontario, Canada
Curr Genet 26:415-21
..Based on the vital role that dUTPase plays in DNA replication, the C. albicans enzyme may be a potentially useful target for the development of novel anti-fungal compounds...
Phenylalkylamine Ca2+ antagonist binding protein. Molecular cloning, tissue distribution, and heterologous expressionM Hanner
Institut für Biochemische Pharmakologie, Universität Innsbruck, Austria
J Biol Chem 270:7551-7
Institut für Biochemische Pharmakologie, Universität Innsbruck, Austria
J Biol Chem 270:7551-7
..EBP is suggested to be the first structurally characterized member of a family of high affinity microsomal drug acceptor proteins carrying so called sigma-binding sites...
Purification, properties and primary structure of thioredoxin from Aspergillus nidulansP Le Marechal
Laboratoire de Physiologie Végétale Moléculaire, Université Paris Sud, Orsay, France
Eur J Biochem 210:421-9
Laboratoire de Physiologie Végétale Moléculaire, Université Paris Sud, Orsay, France
Eur J Biochem 210:421-9
..Compared to thioredoxins from other sources, the protein from A. nidulans displays a maximal sequence similarity with that from yeast (45%)...
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