Research Topics

Jinlin Zhou

Summary

Publications

  1. Malik M, Nawaz M, Hassan I, Zhang H, Gong H, Cao J, et al. A microRNA profile of saliva and role of miR-375 in Haemaphysalis longicornis (Ixodida: Ixodidae). Parasit Vectors. 2019;12:68 pubmed publisher
    ..The identification and characterization of miRNA in tick saliva may help to reveal the molecular mechanisms of interactions among ticks, pathogens and hosts, and suggest new vaccine strategies to control tick-borne diseases. ..
  2. Wang Y, Zhou Y, Gong H, Cao J, Zhang H, Li X, et al. Functional characterization of a cystatin from the tick Rhipicephalus haemaphysaloides. Parasit Vectors. 2015;8:140 pubmed publisher
    ..A disruption of the RHcyst-1 gene showed a significant decrease in the rate of tick hatching. Our results suggested that RHcyst-1 may be involved in the early embryonic development of ticks. ..
  3. Cao J, Yang Q, Zhang J, Zhou Y, Zhang H, Gong H, et al. Seroprevalence survey of Babesia gibsoni infection and tick species in dogs in East China. Vet Parasitol. 2015;214:12-5 pubmed publisher
    ..58%) and Rhipicephalus hemaphysaloides (10.7%). Besides adult, larval and nymph stages of ticks were also recorded on dogs. This is the first report of seroprevalence of canine B. gibsoni infection and tick species in dogs in China. ..
  4. Zhao S, Gong H, Zhou Y, Zhang H, Cao J, Zhou J. Identification of a thioredoxin reductase from Babesia microti during mammalian infection. Parasitol Res. 2016;115:3219-27 pubmed publisher
    ..microti thus reducing the incidence of babesiosis. ..
  5. Zhang H, Wang Z, Gong H, Cao J, Zhou Y, Zhou J. Identification and functional study of a novel 2-cys peroxiredoxin (BmTPx-1) of Babesia microti. Exp Parasitol. 2016;170:21-27 pubmed publisher
    ..These results suggest that BmTPx-1 has a great impact on protecting parasites from oxidative stress in the erythrocytic stage. ..
  6. Wang Y, Li Z, Zhou Y, Cao J, Zhang H, Gong H, et al. Specific histamine binding activity of a new lipocalin from Hyalomma asiaticum (Ixodidae) and therapeutic effects on allergic asthma in mice. Parasit Vectors. 2016;9:506 pubmed publisher
    ..Ha24 is a new tick lipocalin with specific histamine binding activity that can provide relief from host inflammation response. ..
  7. Huang J, Xiong K, Zhang H, Zhao Y, Cao J, Gong H, et al. Molecular characterization of Babesia microti thioredoxin (BmTrx2) and its expression patterns induced by antiprotozoal drugs. Parasit Vectors. 2018;11:38 pubmed publisher
    ..Our results indicate that BmTrx2 is a functional enzyme with antioxidant activity and may be involved in the response of B. microti to anti-parasite drugs. ..
  8. Yu X, Gong H, Zhou Y, Zhang H, Cao J, Zhou J. Differential sialotranscriptomes of unfed and fed Rhipicephalus haemaphysaloides, with particular regard to differentially expressed genes of cysteine proteases. Parasit Vectors. 2015;8:597 pubmed publisher
  9. Lu P, Zhou Y, Yu Y, Cao J, Zhang H, Gong H, et al. RNA interference and the vaccine effect of a subolesin homolog from the tick Rhipicephalus haemaphysaloides. Exp Appl Acarol. 2016;68:113-26 pubmed publisher
    ..These results encourage further studies of using subolesin to control tick infestations in China. ..

More Information

Publications16

  1. Zhou Y, Zhang H, Cao J, Gong H, Zhou J. Epidemiology of toxoplasmosis: role of the tick Haemaphysalis longicornis. Infect Dis Poverty. 2016;5:14 pubmed publisher
    ..gondii to hosts, however, ingestion of infected ticks may be a transmission route between ticks and other common hosts. The T. gondii infection in ticks could serve as a reservoir for toxoplasmosis transmission. ..
  2. Zhang Y, Cui J, Zhou Y, Cao J, Gong H, Zhang H, et al. Liposome mediated double-stranded RNA delivery to silence ribosomal protein P0 in the tick Rhipicephalus haemaphysaloides. Ticks Tick Borne Dis. 2018;9:638-644 pubmed publisher
    ..The effects of P0 dsRNA treatment on ticks were found to be significant on blood feeding, molting or reproduction. These data show that anti-tick agents based on dsRNAs could have potential use in tick control. ..
  3. Huang J, Xiong K, Zhang H, Zhao Y, Cao J, Zhou Y, et al. Babesia microti thioredoxin 3 is an effective antioxidant and involved in the response to antiprotozoal drugs. Ticks Tick Borne Dis. 2018;9:645-653 pubmed publisher
    ..The results of the present study demonstrate that BmTrx3 is a functional enzyme with antioxidant activity and may be involved in the response of B. microti to anti-parasite drugs. ..
  4. Zhou J, Zhou Y, Cao J, Zhang H, Yu Y. Distinctive microRNA profiles in the salivary glands of Haemaphysalis longicornis related to tick blood-feeding. Exp Appl Acarol. 2013;59:339-49 pubmed publisher
    ..Our data provide an important resource for a more detailed functional analysis of miRNAs in this species...
  5. Zhang H, Qiao R, Gong H, Cao J, Zhou Y, Zhou J. Identification and anticoagulant activity of a novel Kunitz-type protein HA11 from the salivary gland of the tick Hyalomma asiaticum. Exp Appl Acarol. 2017;71:71-85 pubmed publisher
    ..These results suggest HA11 is a novel Kunitz-type anticoagulant protein involved in tick blood feeding that may have potential as an anticoagulant drug or vaccine. ..
  6. Wang F, Lu X, Guo F, Gong H, Zhang H, Zhou Y, et al. The immunomodulatory protein RH36 is relating to blood-feeding success and oviposition in hard ticks. Vet Parasitol. 2017;240:49-59 pubmed publisher
    ..These results indicate that RH36 is a novel member of immunosuppressant proteins and affects tick blood feeding and oviposition. ..
  7. Yu X, Zhou Y, Cao J, Zhang H, Gong H, Zhou J. Caspase-1 participates in apoptosis of salivary glands in Rhipicephalus haemaphysaloides. Parasit Vectors. 2017;10:225 pubmed publisher
    ..haemaphysaloides and the dynamic changes in cysteine proteases in this activity. Cysteine proteases were involved in this process, especially caspase-1. Caspase-1 participated in the apoptosis of salivary glands. ..