Forced-air warming and fluid warming minimize core hypothermia during abdominal surgeryJing Zhao
Department of Anesthesiology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100730
Chin Med Sci J 20:261-4. 2005
..To evaluate the effect of intraoperative combined forced-air warming and fluid warming system on patient's core temperature, blood loss, transfusion demand, extubation time, and incidence of postoperative shivering...
- Intrathecal glycine significantly decreases the minimum alveolar concentration of isoflurane in rats
Jing Zhao
Department of Anesthesiology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100730
Chin Med Sci J 23:16-8. 2008
..To evaluate the effect of intrathecal administration of glycine on the minimum alveolar concentration (MAC) of isoflurane in rats...
- Respiratory burst activity of polymorphonuclear cells is dependent on the cell preparation technique
J Zhao
Department of Anaesthesiology, Peking Union Medical College Hospital, Eastern location, Beijing, China
Acta Anaesthesiol Scand 47:702-6. 2003
..The differences could be caused by the cell preparation methods and the aim of this study was to compare two techniques...
- [The effect of intraoperative warming on patient core temperature]
Li Xu
Department of Anesthesiology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100730, China
Zhonghua Wai Ke Za Zhi 42:1010-3. 2004
..059, P = 0.008). CONCLUSION: Fluid warming system and forced-air warming system can effectively maintain normothermia during the surgery and then help to reduce the extubation time and postoperative shivering...
New insight into the genes susceptible to asthmaMing Liang Gu
Key Laboratory of Genome Science and Information, Beijing Institute of Genomics, Chinese Academy of Sciences, Beijing, China
J Asthma 47:113-6. 2010
....
- Urotensin II is an autocrine/paracrine growth factor for aortic adventitia of rat
Yonggang Zhang
Department of Cardiovascular Diseases, First Affiliated Hospital, Shantou University Medical College, Shantou, Guangdong 515041, China
Regul Pept 151:88-94. 2008
....
- [The cloning and expression of the truncated human bid gene and its pro-apoptotic effect on Hela cells]
Xiu Chun Qiu
Department of Biochemistry and Molecular Biology, Fourth Military Medical University, Xi an 710032, China
Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi 20:19-22. 2004
..To explore the expression of the truncated bid gene and its pro-apoptotic effect on Hela cells...
- Synthesis and insecticidal activity of new 4-hydroxy-2H-1-benzopyran-2-one derivatives
Meijing Wang
Department of Chemistry, Northeastern University, Shenyang City, People s Republic of China
Appl Biochem Biotechnol 159:768-77. 2009
..in Br J Haematol 132:277-285, 2006). The structures of synthesized compounds were confirmed by IR, (1)H NMR. The compounds were also evaluated for their anticoagulant and acute biologic activity (Lipton et al., JAMA 252:3004-3005, 3)...
- Differential gene expression profiles of DNA repair genes in esophageal cancer cells after X-ray irradiation
Hai Zhang
Department of Pharmacology, Hebei North University, Zhangjiakou, Hebei 075000, PR China
Chin J Cancer 29:865-72. 2010
..This paper was to analyze the differential expressions of DNA repair genes in esophageal carcinoma cells at different time after X-ray irradiation, and to investigate the role of these DNA repair genes in radiation resistance...
- Identification of differentially expressed genes related to radioresistance of human esophageal cancer cells
Hong Zhen Li
Department of Radiation Oncology, Peking University First Hospital, Beijing 100034, PR China
Chin J Cancer 29:882-8. 2010
....
- Mapping and localization of susceptible genes in asthma
Ming Liang Gu
Beijing Institute of Genomics, Chinese Academy of Sciences, Beijing 100029, China
Chin Med J (Engl) 124:132-43. 2011
..To elucidate the development of mapping and localization of susceptible genes on chromosomes to asthma related phenotypes...
- Evaluation of entropy for monitoring the depth of anesthesia compared with bispectral index: a multicenter clinical trial
Jian Dong Gao
Department of Anesthesiology, Beijing Chaoyang Hospital, Capital Medical University, Beijing 100020, China
Chin Med J (Engl) 125:1389-92. 2012
..Our study compared entropy with classical bispectral index (BIS) in reduction of myoelectrical interference and noxious stimuli with EEG signals...
Molecular and cellular mechanisms of the age-dependency of opioid analgesia and toleranceJing Zhao
Department of Anesthesia, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100730, China
Mol Pain 8:38. 2012
....
- Purification and characterization of a novel hypersensitive response-inducing elicitor from Magnaporthe oryzae that triggers defense response in rice
Mingjia Chen
Key Laboratory of Integrated Pest Management in Crops, Ministry of Agriculture, Institute of Plant Protection, Chinses Academy of Agricultural Sciences, Beijing, China
PLoS ONE 7:e37654. 2012
..Magnaporthe oryzae, the rice blast fungus, might secrete certain proteins related to plant-fungal pathogen interactions...
- Anesthetic considerations of an emergency decompressive craniotomy complicated with Ebstein's anomaly and atrial septal defect
Xin Xin
Department of Anesthesiology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China
Chin Med J (Engl) 124:615-7. 2011
..We report a case of emergency decompressive craniotomy in a patient with EA. Anesthesiologists should pay special attention to the complications and anesthetic management during the non-cardiac surgeries performed in EA patients...
- Very low prevalence of asthma and allergies in schoolchildren from rural Beijing, China
Yu Ma
Capital Institute of Pediatrics, Beijing, China
Pediatr Pulmonol 44:793-9. 2009
..The prevalence of asthma is relatively low in the Chinese population. There is consistent evidence that growing up on a farm is associated with protection against the subsequent development of asthma...
- Altered L-arginine/nitric oxide synthase/nitric oxide pathway in the vascular adventitia of rats with sepsis
Yue Xia Jia
Institute of Cardiovascular Research, Peking University First Hospital, Beijing, China
Clin Exp Pharmacol Physiol 33:1202-8. 2006
..01). 6. The Arg/NOS/NO pathway was activated in the vascular adventitia of rats with sepsis shock. The L-Arg/NOS/NO pathway in the aortic adventitia may play an important role in the pathogenesis of sepsis and septic shock...
- Expression of gonadotropin-releasing hormone receptor and effect of gonadotropin-releasing hormone analogue on proliferation of cultured gastric smooth muscle cells of rats
Lei Chen
Department of Biological Science and Biotechnology, Tsinghua University, Beijing, 100084, China
World J Gastroenterol 10:1780-4. 2004
..To investigate the expression of gonadotropin-releasing hormone (GnRH) receptor and the effects of GnRH analog (alarelin) on proliferation of cultured gastric smooth muscle cells (GSMC) of rats...
- Therapeutic application of gene silencing MMP-9 in a middle cerebral artery occlusion-induced focal ischemia rat model
Qin Hu
Department of Anatomy and Embryology, Peking University Health Science Center, Beijing, China
Exp Neurol 216:35-46. 2009
..Our findings provide evidence that a liposomal formulation of siRNA might be used in vivo to silence the MMP-9 gene and could potentially serve as an important therapeutic alternative in patients with cerebral ischemia...
- Effects of bicyclol on liver regeneration after partial hepatectomy in rats
Xiao Min Yao
Department of New Drug Development, Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, No 1, Xian Nong Tan Street, Beijing, 100050, People s Republic of China
Dig Dis Sci 54:774-81. 2009
..These results suggested that bicyclol had a beneficial effect on liver regenerative capacity of the remnant liver tissue after hepatectomy, probably due to its antioxidative property...
- Simultaneous determination of seven fluoroquinolones in royal jelly by ultrasonic-assisted extraction and liquid chromatography with fluorescence detection
Jinhui Zhou
Bee Research Institute, Chinese Academy of Agricultural Sciences, Bee Product Quality Supervision and Testing Center, Ministry of Agriculture, Beijing, China
J Sep Sci 32:955-64. 2009
..6 ng/g. Unexpectedly, however, difloxacin was found at concentrations of about 46.8 ng/g in one sample although it is rarely used in beekeeping. The presented method was successfully applied to quantify FQs in real royal jelly samples...
- Lentiviral vectors for delivery of genes into neonatal and adult ventricular cardiac myocytes in vitro and in vivo
Jing Zhao
Department of Medicine, Addenbrooke's Hospital, Hills Road, Cambridge, CB2 2QQ, UK
Basic Res Cardiol 97:348-58. 2002
....
- [Effect of the truncated human apoptosis-inducing factor expression on apoptosis of HeLa cells]
Cui-juan Yu
Department of Biochemistry and Molecular Biology, Fourth Military Medical University, Xi'an 710032, China
Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi 19:10-3. 2003
..CONCLUSION: The expression of the truncated human AIF gene can induce apoptosis of the transfected human HeLa cells...
- Apelin protects myocardial injury induced by isoproterenol in rats
Yue Xia Jia
Institute of Cardiovascular Research, Peking University First Hospital, Beijing 100034, China
Regul Pept 133:147-54. 2006
..Apelin could have a cardioprotective effect, and the apelin-APJ system may be a new therapeutic target in myocardial injury and heart failure...
- Recombinant immunoproapoptotic proteins with furin site can translocate and kill HER2-positive cancer cells
Tao Wang
State Key Laboratory of Cancer Biology, Department of Biochemistry and Molecular Biology, Fourth Military Medical University, Xi an, China
Cancer Res 67:11830-9. 2007
..We conclude that the new class of immunoproapoptotic proteins show comparable activity with PEA II-containing counterpart and provide an attractive therapeutic alternative as they contain much less exogenous fragments...
- [Establishment of Hela cell line inducibly expressing human active granzyme B]
Zhi Wang
Department of Biochemistry and Molecular Biology, Faculty of Preclinical Medicine, Fourth Military Medical University, Xi'an 710032, China
Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi 20:621-4. 2004
..CONCLUSION: The establishment of inducible expression system for active granzyme B lays the foundation for further research on biological function of granzyme B...
- [Construction, expression and cell growth inhibition of translocating peptide/granzyme B fusion protein gene]
Jing Zhao
Department of Biochemistry and Molecular Biology, Fourth Military Medical University, Xi'an 710032 China
Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi 20:394-7, 401. 2004
..RESULTS: Transient expression of PE II-GrBa resulted in cytoskeleton abnormality, cell growth inhibition, and apoptosis in some cells. CONCLUSION: Expression of PE II-GrBa fusion protein can inhibit cell growth...
- The antioxidant effects of ribonuclease inhibitor
Xiu Yun Cui
Department of Biochemistry and Molecular Biology, Dalian Medical University, Dalian 116027, China
Free Radic Res 37:1079-85. 2003
..These results suggest that RI has the protective role against mouse hepatic damage induced by CC14. The anti-oxidative effects of RI may play an important role in cell protection from per-oxidative injuries...
- [Construction and expression of recombinant antibody/granzyme B containing truncated translocating peptide]
Li Zhang
Department of Biochemistry and Molecular Biology, Fourth Military Medical University, Xi an 710032, China
Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi 19:434-6. 2003
..To construct an eukaryotic expression vector for recombinant antibody/granzyme B gene containing truncated translocating peptide and express it in HER-2(+) SKBR-3 cells and HER-2(-) Hela cells...
- Effects of taurine and homocysteine on calcium homeostasis and hydrogen peroxide and superoxide anions in rat myocardial mitochondria
Lin Chang
Institute of Cardiovascular Disease Research, The First Hospital, Beijing, People s Republic of China
Clin Exp Pharmacol Physiol 31:237-43. 2004
..Our results may show an important mechanism for the cardiovascular protective effects of taurine...
- Secreted antibody/granzyme B fusion protein stimulates selective killing of HER2-overexpressing tumor cells
Jing Zhao
Departments of Biochemistry and Molecular Biology and Immunology, The Fourth Military Medical University, Xi an 710032, China
J Biol Chem 279:21343-8. 2004
....
- Percutaneous imaging-guided radiofrequency ablation in patients with colorectal pulmonary metastases: 1-year follow-up
Karin Steinke
University of New South Wales, Departments of Surgery (KS, JK, JZ, DM, Radiology (DG, WC, and Medical Oncology (PC, The St. George Hospital, Sydney, New South Wales, Australia
Ann Surg Oncol 11:207-12. 2004
..A significant proportion of patients show good evidence of successful local control at 1 year...
- A novel butyrolactone derivative inhibited apoptosis and depressed integrin beta4 expression in vascular endothelial cells
Weiwei Wang
Institute of Developmental Biology, School of Life Science, Shandong University, Jinan 250100, China
Bioorg Med Chem Lett 17:482-5. 2007
..The data suggested that 3BDO (20-60 microg/ml) could inhibit VEC apoptosis and suppress integrin beta4 expression, but it could not depress the ROS level induced by deprivation of serum and FGF-2...
- Neutrophils are stimulated by syncytiotrophoblast microvillous membranes to generate superoxide radicals in women with preeclampsia
Amal S Aly
Center for Research on Reproduction and Women's Health, University of Pennsylvania School of Medicine, Philadelphia, 19104, USA
Am J Obstet Gynecol 190:252-8. 2004
..007). CONCLUSION: STBMs in maternal blood induce neutrophils to generate superoxide radicals that may cause endothelial dysfunction in women with preeclampsia...
- Chromatin reorganization accompanying cellular dedifferentiation is associated with modifications of histone H3, redistribution of HP1, and activation of E2F-target genes
Leor Williams
Department of Plant Sciences, The Weizmann Institute of Science, Rehovot, Israel
Dev Dyn 228:113-20. 2003
..We propose that chromatin reorganization is central for reversion of the differentiation process leading to resetting of the gene expression program and activation of silent genes...
- Therapeutic effects of ghrelin on endotoxic shock in rats
Lin Chang
Cardiovascular Research Institute, The First Hospital of Peking University, Beijing 100034, PR China
Eur J Pharmacol 473:171-6. 2003
..The results suggest that ghrelin could have therapeutic value for endotoxic shock...
- Specific tumoricidal activity of a secreted proapoptotic protein consisting of HER2 antibody and constitutively active caspase-3
Lin-Tao Jia
Department of Biochemistry and Molecular Biology, Fourth Military Medical University, Xi'an 710032, China
Cancer Res 63:3257-62. 2003
..These findings provide a compelling rationale for therapeutic protocols designed for erbB2/HER2-positive tumors...
- Effect of caffeic acid phenethyl ester on proliferation and apoptosis of hepatic stellate cells in vitro
Wen Xing Zhao
Medical Laboratory of KUNMING General Hospital, Chengdu Command, 212 Daguan Road, Kunming 650032, Yunnan Province, China
World J Gastroenterol 9:1278-81. 2003
..To investigate the role of nuclear factor-kappaB (NF-kappaB) inhibitor caffeic acid phenethy1 ester (CAPE) in the proliferation, collagen synthesis and apoptosis of hepatic stellate cells (HSCs) of rats...
- Over-expression of LPTS-L in hepatocellular carcinoma cell line SMMC-7721 induces crisis
Cheng Liao
State Key Laboratory of Molecular Biology, Institute of Biochemistry and Cell Biology, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, China
World J Gastroenterol 8:1050-2. 2002
..To evaluate the function of the longer transcripts LPTS-L in hepatocellular carcinoma cell line SMMC-7721...
- Hydrogen sulfide inhibits myocardial injury induced by homocysteine in rats
Lin Chang
Institute of Cardiovascular Research, Peking University, Xishuku Street 8, West District, 100034 Beijing, People s Republic of China
Amino Acids 34:573-85. 2008
....
- Knockdown of integrin beta4 in primary cultured mouse neurons blocks survival and induces apoptosis by elevating NADPH oxidase activity and reactive oxygen species level
Xin Lv
Institute of Developmental Biology, Shandong University, Jinan 250100, China
Int J Biochem Cell Biol 40:689-99. 2008
....
- Antitumor effects of human ribonuclease inhibitor gene transfected on B16 melanoma cells
Jun-Xia Chen
Department of Biochemistry and Molecular Biology, Dalian Medical University, Dalian 116027, Liaoning Province, China
Int J Biochem Cell Biol 37:1219-31. 2005
..These results suggest that ribonuclease inhibitor might be a candidate of tumor suppressor gene in some tissues. RI could become a target gene for gene therapy. Our study may be of biological and clinical importance...
- Coupling of cell migration with neurogenesis by proneural bHLH factors
Weihong Ge
Mental Retardation Research Center, Dept of Psychiatry and Biobehavioral Sciences, Neuropsychiatric Institute, David Geffen School of Medicine, University of California Los Angeles, 635 Charles E Young Drive South, Los Angeles, CA 90095, USA
Proc Natl Acad Sci U S A 103:1319-24. 2006
..Collectively, these data suggest that transcription programs for neurogenesis and migration are regulated by bHLH factors through partially distinct mechanisms...
- Safrole oxide induced human umbilical vein vascular endothelial cell differentiation into neuron-like cells by depressing the reactive oxygen species level at the low concentration
Le Su
Institute of Developmental Biology, School of Life Science, Shandong University, Jinan 250100, China
Biochim Biophys Acta 1763:247-53. 2006
..Furthermore, our data suggested that safrole oxide might perform this function by depressing intracellular ROS levels instead of by affecting cell growth or apoptosis signal pathways...
- Morphine promotes Jurkat cell apoptosis through pro-apoptotic FADD/P53 and anti-apoptotic PI3K/Akt/NF-kappaB pathways
Deling Yin
Department of Internal Medicine, James Quillen College of Medicine, East Tennessee State University, P O Box 70622, Johnson City, TN 37614, United States
J Neuroimmunol 174:101-7. 2006
..Our study thus demonstrates that morphine induces Jurkat cell apoptosis through FADD/p53, anti-apoptotic PI3K/Akt and NF-kappaB pathways...
- Expression of soluble and functional snake venom fibrinolytic enzyme fibrolase via the co-expression of DsbC in Escherichia coli
Shou-Tao Zhang
Northwest A and F University, Key Laboratory of Agricultural Molecular Biology in Shaanxi Province, Yangling, Shaanxi Province, 712100, P.R. China
Protein Pept Lett 13:559-63. 2006
..Fibrinolytic activity of recombinant fibrolase was demonstrated using fibrin plate assays and fibrinogen hydrolysis...
- Amplification and application of the HMG box of bovine SRY gene for sex determination
Wenfa Lu
College of Animal Science and Technology, Jilin Agricultural University, Changchun 130118, PR China
Anim Reprod Sci 100:186-91. 2007
....
- [Pro-apoptotic efficiencies of three reconstructed human caspase-8 on cervical cancer cell line HeLa]
Jun-hao Gui
Clinical Medical Research Institute, Urumqi General Hospital, Lanzhou Command, Urumqi, Xinjiang, 830000, P. R. China
Ai Zheng 24:160-5. 2005
..CONCLUSION:Rev8 and Rev8L molecules have similar pro-apoptotic effects and efficiencies, but over-expressed Casp8CD had no significant pro-apoptotic effects...
- Distribution, cloning and sequencing of GnRH, its receptor, and effects of gastric acid secretion of GnRH analogue in gastric parietal cells of rats
Lei Chen
Department of Histology and Embryology, The Fourth Military Medical University, Xi an, 710032, People s Republic of China
Life Sci 76:1351-65. 2005
..Our data suggest that GnRH could be produced by gastric parietal cells of rats and may modulate physiological function of gastric parietal cells of rats through autocrinal and paracrinal way...
- Safrole oxide induces neuronal apoptosis through inhibition of integrin beta4/SOD activity and elevation of ROS/NADPH oxidase activity
Le Su
Institute of Developmental Biology, School of Life Science, Shandong University, Jinan, China
Life Sci 80:999-1006. 2007
..Our study thus demonstrates that safrole oxide induces neuronal apoptosis through integrin beta4, ROS, NADPH, and MnSOD...
- [Relationship between three thrombophilic gene mutations and unexplained recurrent early spontaneous abortion]
Li Xu
Reproductive Research Center, Qingdao Research Institute for Family Planning, Qingdao 266071, China
Zhonghua Fu Chan Ke Za Zhi 42:180-3. 2007
..To explore the relationship of methylenetetrahydrofolate reductase (MTHFR) gene C677T, factor V (FV) gene G1691A and prothrombin (PT) gene G20210A polymorphisms to unexplained recurrent early spontaneous abortion (URESA)...
- Lentivirus-mediated gene expression
Jing Zhao
Department of Medicine, Addenbrooke s Hospital, University of Cambridge, UK
Methods Mol Biol 366:343-55. 2007
..Their ease of cloning and well-understood molecular biology have made them highly suitable for gene delivery to the heart...
- Targeted inhibition of HBV gene expression by single-chain antibody mediated small interfering RNA delivery
Wei Hong Wen
State Key Laboratory of Cancer Biology, Department of Immunology, Xijing Hospital, Fourth Military Medical University, Xi an, China
Hepatology 46:84-94. 2007
..CONCLUSION: Our results describe a potential method for the targeted delivery of siRNA or siRNA-producing plasmids against HBV, using anti-HBsAg fusion proteins...
- A novel Phex mutation with defective glycosylation causes hypophosphatemia and rickets in mice
Xiwen Xiong
Model Animal Research Center, Nanjing University, 12 Xuefu Road, Pukou District, Nanjing, 210061, PR China
J Biomed Sci 15:47-59. 2008
..Taken together, the Pug mutant directly confirms the role of Phex in phosphate homeostasis and normal skeletal development and may serves as a new disease model of human hypophosphatemic rickets...
- Apelin activates L-arginine/nitric oxide synthase/nitric oxide pathway in rat aortas
Yue Xia Jia
Institute of Cardiovascular Research, Peking University First Hospital, Beijing 100034, China
Peptides 28:2023-9. 2007
..05) and 319% (p<0.01), respectively. Collectively, these results demonstrate that apelin directly activated the vascular L-Arg/NOS/NO pathway, which could be one of the important mechanisms of apelin-regulated vascular function...
- Spectroscopic insights into lead(II) coordination by the selective lead(II)-binding protein PbrR691
Peng R Chen
Department of Chemistry, The University of Chicago, 5735 South Ellis Avenue, Chicago, Illinois 60637, USA
J Am Chem Soc 129:12350-1. 2007
- Hyphal growth patterns and recurrence of fungal keratitis after lamellar keratoplasty
Lixin Xie
State Key Laboratory Cultivation Base, Shandong Provincial Key Laboratory of Ophthalmology, Shandong Eye Institute, Qingdao, China
Ophthalmology 115:983-7. 2008
..To evaluate growth patterns of fungal pathogens in corneas and recurrence of fungal keratitis after lamellar keratoplasty (LK)...
- A novel functional polymorphism in the Cdc6 promoter is associated with the risk for hepatocellular carcinoma
Xing Dong Xiong
Key Laboratory of Gene Engineering of the Ministry of Education, State Key Laboratory of Biocontrol, School of Life Sciences, Sun Yat Sen University, Guangzhou, PR China
Mutat Res 643:70-4. 2008
..Our findings suggest that the -515A>G polymorphism may affect the Cdc6 promoter binding affinity with nuclear protein(s) and in turn the Cdc6 expression, which consequently modulates the individual's susceptibility to HCC...
