Zhuohua Zhang

Summary

Publications

  1. pmc Dispensable role of Drosophila ortholog of LRRK2 kinase activity in survival of dopaminergic neurons
    Danling Wang
    Burnham Institute for Medical Research, 10901 North Torrey Pines Road, La Jolla, California 92037, USA
    Mol Neurodegener 3:3. 2008
  2. pmc Regulation of parkin and PINK1 by neddylation
    Yeun Su Choo
    Sanford Burnham Medical Research Institute, 10901 N Torrey Pines Road, La Jolla, CA 92037, USA
    Hum Mol Genet 21:2514-23. 2012
  3. doi Critical role of PINK1 in regulating Parkin protein levels in vivo
    Yeun Su Choo
    Sanford Burnham Medical Research Institute, 10901 N Torrey Pines Rd, La Jolla, CA 92037, USA
    Arch Neurol 68:684-5. 2011
  4. pmc Antioxidants protect PINK1-dependent dopaminergic neurons in Drosophila
    Danling Wang
    Burnham Institute for Medical Research, 10901 North Torrey Pines Road, La Jolla, CA 92037, USA
    Proc Natl Acad Sci U S A 103:13520-5. 2006
  5. pmc Parkin, PINK1, and DJ-1 form a ubiquitin E3 ligase complex promoting unfolded protein degradation
    Hui Xiong
    Burnham Institute for Medical Research, 10901 N Torrey Pines Road, La Jolla, CA 92037, USA
    J Clin Invest 119:650-60. 2009

Collaborators

Detail Information

Publications5

  1. pmc Dispensable role of Drosophila ortholog of LRRK2 kinase activity in survival of dopaminergic neurons
    Danling Wang
    Burnham Institute for Medical Research, 10901 North Torrey Pines Road, La Jolla, California 92037, USA
    Mol Neurodegener 3:3. 2008
    ..Increased LRRK2 kinase activity plays a critical role in pathogenic LRRK2 mutant-induced neurodegeneration in vitro. Little is known about the physiological function of LRRK2...
  2. pmc Regulation of parkin and PINK1 by neddylation
    Yeun Su Choo
    Sanford Burnham Medical Research Institute, 10901 N Torrey Pines Road, La Jolla, CA 92037, USA
    Hum Mol Genet 21:2514-23. 2012
    ..Together, these results suggest that parkin and PINK1 are regulated by neddylation and that impaired NEDD8 modification of these proteins likely contributes to PD pathogenesis...
  3. doi Critical role of PINK1 in regulating Parkin protein levels in vivo
    Yeun Su Choo
    Sanford Burnham Medical Research Institute, 10901 N Torrey Pines Rd, La Jolla, CA 92037, USA
    Arch Neurol 68:684-5. 2011
  4. pmc Antioxidants protect PINK1-dependent dopaminergic neurons in Drosophila
    Danling Wang
    Burnham Institute for Medical Research, 10901 North Torrey Pines Road, La Jolla, CA 92037, USA
    Proc Natl Acad Sci U S A 103:13520-5. 2006
    ....
  5. pmc Parkin, PINK1, and DJ-1 form a ubiquitin E3 ligase complex promoting unfolded protein degradation
    Hui Xiong
    Burnham Institute for Medical Research, 10901 N Torrey Pines Road, La Jolla, CA 92037, USA
    J Clin Invest 119:650-60. 2009
    ....