Jiapu Zhang

Summary

Publications

  1. ncbi request reprint The structural stability of wild-type horse prion protein
    Jiapu Zhang
    School of Sciences, Information Technology and Engineering, University of Ballarat, Mount Helen, Ballarat, Victoria 3353, Australia
    J Biomol Struct Dyn 29:369-77. 2011
  2. doi request reprint Molecular dynamics studies on 3D structures of the hydrophobic region PrP(109-136)
    Jiapu Zhang
    Graduate School of Sciences, Information Technology and Engineering, CIAO, The University of Ballarat, Mt Helen Campus, Victoria 3353, Australia
    Acta Biochim Biophys Sin (Shanghai) 45:509-19. 2013
  3. doi request reprint Studies on the structural stability of rabbit prion probed by molecular dynamics simulations of its wild-type and mutants
    Jiapu Zhang
    Victorian Life Sciences Computation Initiative, The University of Melbourne, 1 Hull Road, Croydon, VIC 3136, Australia
    J Theor Biol 264:119-22. 2010
  4. doi request reprint Optimal molecular structures of prion AGAAAAGA amyloid fibrils formatted by simulated annealing
    Jiapu Zhang
    Victorian Life Sciences Computation Initiative, The University of Melbourne, 1 3 Hull Road, Croydon, Victoria, VIC 3136, Australia
    J Mol Model 17:173-9. 2011
  5. doi request reprint Comparison studies of the structural stability of rabbit prion protein with human and mouse prion proteins
    Jiapu Zhang
    Centre for Informatics and Applied Optimization, Graduate School of Information Technology and Mathematics Sciences, The University of Ballarat, Mt Helen Campus, Victoria 3353, Australia
    J Theor Biol 269:88-95. 2011
  6. doi request reprint Optimal atomic-resolution structures of prion AGAAAAGA amyloid fibrils
    Jiapu Zhang
    School of Sciences, Information Technology, and Engineering, The University of Ballarat, Mount Helen Campus, Victoria 3353, Australia
    J Theor Biol 279:17-28. 2011
  7. ncbi request reprint Molecular dynamics studies on the structural stability of wild-type dog prion protein
    Jiapu Zhang
    School of Sciences, Information Technology and Engineering, University of Ballarat, Mount Helen, Ballarat, Victoria 3353, Australia
    J Biomol Struct Dyn 28:861-9. 2011
  8. doi request reprint A novel canonical dual computational approach for prion AGAAAAGA amyloid fibril molecular modeling
    Jiapu Zhang
    Centre in Informatics and Applied Optimization, Graduate School of Sciences, Informatics Technology and Engineering, University of Ballarat, Mount Helen, VIC 3353, Australia
    J Theor Biol 284:149-57. 2011
  9. ncbi request reprint Studies on the structural stability of rabbit prion probed by molecular dynamics simulations
    Jiapu Zhang
    Centre for Informatics and Applied Optimization, School of ITMS, The University of Ballarat, 15 172 Princes St, Carlton North VIC 3054, Australia
    J Biomol Struct Dyn 27:159-62. 2009
  10. doi request reprint CYP1A/regucalcin gene expression and edema formation in zebrafish embryos exposed to 2,3,7,8-Tetrachlorodibenzo-p-dioxin
    Y D Wu
    Key Lab of Subtropical Agriculture and Environment, Ministry of Agriculture, Huazhong Agricultural University, Wuhan 430070, People s Republic of China
    Bull Environ Contam Toxicol 80:482-6. 2008

Collaborators

Detail Information

Publications24

  1. ncbi request reprint The structural stability of wild-type horse prion protein
    Jiapu Zhang
    School of Sciences, Information Technology and Engineering, University of Ballarat, Mount Helen, Ballarat, Victoria 3353, Australia
    J Biomol Struct Dyn 29:369-77. 2011
    ..Rich databases of salt bridges, hydrogen bonds and hydrophobic contacts for horse prion protein can be found in this paper...
  2. doi request reprint Molecular dynamics studies on 3D structures of the hydrophobic region PrP(109-136)
    Jiapu Zhang
    Graduate School of Sciences, Information Technology and Engineering, CIAO, The University of Ballarat, Mt Helen Campus, Victoria 3353, Australia
    Acta Biochim Biophys Sin (Shanghai) 45:509-19. 2013
    ..This article gives detailed reviews on the PrP(109-136) region and presents the studies of its three-dimensional structures and structural dynamics...
  3. doi request reprint Studies on the structural stability of rabbit prion probed by molecular dynamics simulations of its wild-type and mutants
    Jiapu Zhang
    Victorian Life Sciences Computation Initiative, The University of Melbourne, 1 Hull Road, Croydon, VIC 3136, Australia
    J Theor Biol 264:119-22. 2010
    ..Simulation results confirm the structural stability of wild-type rabbit prion, and show that the salt bridge between D177 and R163 greatly contributes to the structural stability of rabbit prion protein...
  4. doi request reprint Optimal molecular structures of prion AGAAAAGA amyloid fibrils formatted by simulated annealing
    Jiapu Zhang
    Victorian Life Sciences Computation Initiative, The University of Melbourne, 1 3 Hull Road, Croydon, Victoria, VIC 3136, Australia
    J Mol Model 17:173-9. 2011
    ..The results presented here confirm standard simulated annealing as an effective tool in molecular modeling. The three constructed models for amyloid fibrils may be useful in furthering the goals of medicinal chemistry in this field...
  5. doi request reprint Comparison studies of the structural stability of rabbit prion protein with human and mouse prion proteins
    Jiapu Zhang
    Centre for Informatics and Applied Optimization, Graduate School of Information Technology and Mathematics Sciences, The University of Ballarat, Mt Helen Campus, Victoria 3353, Australia
    J Theor Biol 269:88-95. 2011
    ..Vorberg et al., Journal of Virology 77 (3) (2003) 2003-2009). Thus the study of rabbit prion protein structure to obtain insight into the immunity of rabbits to prion diseases is very important...
  6. doi request reprint Optimal atomic-resolution structures of prion AGAAAAGA amyloid fibrils
    Jiapu Zhang
    School of Sciences, Information Technology, and Engineering, The University of Ballarat, Mount Helen Campus, Victoria 3353, Australia
    J Theor Biol 279:17-28. 2011
    ..The optimal atomic-resolution structures of prion AGAAAAGA amyloid fibils reported in this paper have a value to the scientific community in its drive to find treatments for prion diseases...
  7. ncbi request reprint Molecular dynamics studies on the structural stability of wild-type dog prion protein
    Jiapu Zhang
    School of Sciences, Information Technology and Engineering, University of Ballarat, Mount Helen, Ballarat, Victoria 3353, Australia
    J Biomol Struct Dyn 28:861-9. 2011
    ..We also find that the salt bridges such as D177-R163 contribute to the structural stability of wild-type rabbit prion protein under neutral pH environment...
  8. doi request reprint A novel canonical dual computational approach for prion AGAAAAGA amyloid fibril molecular modeling
    Jiapu Zhang
    Centre in Informatics and Applied Optimization, Graduate School of Sciences, Informatics Technology and Engineering, University of Ballarat, Mount Helen, VIC 3353, Australia
    J Theor Biol 284:149-57. 2011
    ..Overall, this paper presents an important method and provides useful information for treatments of prion diseases...
  9. ncbi request reprint Studies on the structural stability of rabbit prion probed by molecular dynamics simulations
    Jiapu Zhang
    Centre for Informatics and Applied Optimization, School of ITMS, The University of Ballarat, 15 172 Princes St, Carlton North VIC 3054, Australia
    J Biomol Struct Dyn 27:159-62. 2009
    ..This paper studies the inhibition mechanism of rabbit prion at molecular structural level by molecular dynamics simulations...
  10. doi request reprint CYP1A/regucalcin gene expression and edema formation in zebrafish embryos exposed to 2,3,7,8-Tetrachlorodibenzo-p-dioxin
    Y D Wu
    Key Lab of Subtropical Agriculture and Environment, Ministry of Agriculture, Huazhong Agricultural University, Wuhan 430070, People s Republic of China
    Bull Environ Contam Toxicol 80:482-6. 2008
    ..Results indicated that the 50 pg/mL TCDD caused severe and visible developmental toxicity. Further research of the long term and low concentration of TCDD exposure is required...
  11. doi request reprint Low dose secondary prophylaxis reduces joint bleeding in severe and moderate haemophilic children: a pilot study in China
    R Wu
    Hemophilia Work Group, Beijing Children s Hospital Affiliated to Capital Medical University, Beijing, China
    Haemophilia 17:70-4. 2011
    ..Low dose secondary prophylaxis is therefore, cost-effective as applied to developing countries such as China, although there are still unresolved issues...
  12. doi request reprint No association of the POLI Thr706Ala polymorphism with the risk of cervical carcinoma
    J Zhang
    Department of Gynecologic Oncology, Women s Hospital, School of Medicine, Zhejiang University, Xueshi Road 2, Hangzhou, Zhejiang 310006, China
    Eur J Surg Oncol 34:916-20. 2008
    ..To investigate the association of repair gene POLI genetic polymorphisms with cervical carcinoma...
  13. ncbi request reprint Selective management of obstructive submandibular sialadenitis
    C Q Yu
    Department of Oral and Maxillofacial Surgery, Shanghai Ninth People s Hospital, Shanghai Jiao Tong University Medical College, 639 Zhi Zao Ju Road, Shanghai 200011, PR China
    Br J Oral Maxillofac Surg 46:46-9. 2008
    ..We aimed to describe the effect of our surgical and sialoendoscopic technique for diagnosis and treatment of chronic obstructive submandibular sialadenitis...
  14. ncbi request reprint [Association of VNTR region of the human serotonin transporter gene with bipolar disorder among the Han Chinese]
    W Liu
    Shanghai Research Center of Life Science, Chinese Academy of Sciences, Shanghai 200031 P R China
    Zhonghua Yi Xue Yi Chuan Xue Za Zhi 15:345-8. 1998
    ..The serotonin transporter gene (SERT) plays an important role in the serotonin uptake into neurons. This paper reports a population and association study among the Han Chinese...
  15. ncbi request reprint [The application of fluorescence in situ hybridization performed on the decolorized G-banding chromosomes in detecting the marker chromosomes of gastric cancer]
    J Xia
    Department of Pathology, Cancer Center, Sun Yat sen University of Medical Science, Guangzhou, Guangdong, P R China
    Zhonghua Yi Xue Yi Chuan Xue Za Zhi 17:274-7. 2000
    ..Using a rapid, accurate method that detects the marker chromosomes of gastric cancer and enhancing the ability of discriminating complicated chromosome rearrangements of gastric cancer...
  16. ncbi request reprint Pig islet xenograft rejection is markedly delayed in macrophage-depleted mice: a study in streptozotocin diabetic animals
    G Wu
    Department of Transplantation Surgery, Huddinge Hospital, Karolinska Institute, Stockholm, Sweden
    Xenotransplantation 7:214-20. 2000
    ..In conclusion, our results suggest that strategies targeting macrophages may facilitate islet xenograft survival. A role for NK cells cannot be excluded, but appears to be of minor importance...
  17. ncbi request reprint Ambient sulfate concentration and chronic disease mortality in Beijing
    J Zhang
    Department of Occupational and Environmental Health Science, Beijing Medical University, PR China
    Sci Total Environ 262:63-71. 2000
    ..Areas with high levels of SO(4)2- experienced higher mortality due to a variety of chronic diseases...
  18. ncbi request reprint A miniature class V flextensional cymbal transducer with directional beam patterns: the double-driver
    J Zhang
    Materials Research Laboratory, The Pennsylvania State University, University Park 16802, USA
    Ultrasonics 39:91-5. 2001
    ..A 3 x 3 double-driver array was constructed to demonstrate that under optimal conditions the array can provide a directional beam pattern with a front-to-back ratio of more than 20 dB...
  19. ncbi request reprint STAT3 exerts two-way regulation in the biological effects of IL-6 in M1 leukemia cells
    J Zhang
    Department of Immunology, Beijing Institute of Basic Medical Sciences, 27 Taiping Road, PO Box 130 3, 100850, Beijing, PR China
    Leuk Res 25:463-72. 2001
    ....
  20. ncbi request reprint [The efficiency of algae removal from drinking water by ferrate]
    B Yuan
    State Key Laboratory of Environmental Aquatic Chemistry, Research Center for Eco Environmental Sciences, Chinese Academy of Sciences, Beijing 100085, China
    Huan Jing Ke Xue 22:78-81. 2001
    ..85%. However this treatment method using ferrate as pre-oxidant overmatched the traditional method prechlorination for algae removal...
  21. ncbi request reprint [Interaction of Se and S forms in rhizospheric soil and their absorption by tobacco]
    Y Ma
    Nanjing Agricultural University, Nanjing 210005
    Ying Yong Sheng Tai Xue Bao 11:253-7. 2000
    ..The S content in the aboveground part of tobacco at its early stage was mainly influenced by soluble and organic S in the rhizosphere...
  22. ncbi request reprint Replacement of the p16 gene in human ovarian cancer cells
    M Wang
    Department of Obstetrics and Gynecology, Second Clinical College of China Medical University, Shenyang 110003, China
    Chin Med J (Engl) 114:857-9. 2001
    ..To study the inhibitory effects of retrovirus-mediated p16 gene on the human ovarian cancer cell line CAOV3...
  23. ncbi request reprint Molecular characterization of MbADGF, a novel member of the adenosine deaminase-related growth factor in the cabbage armyworm, Mamestra brassicae: the functional roles in the midgut cell proliferation
    J Zhang
    Division of Biofunctional Science, Graduate School of Science and Technology, Kobe University, Nada, Kobe, Japan
    Insect Mol Biol 16:351-60. 2007
    ....
  24. ncbi request reprint [Parental origin of extra chromosome 21 in Down syndrome detected by using short tandem repeat DNA polymorphisms after PCR amplification]
    Q Shi
    Department of Biology, Nanjing Normal University, Nanjing, Jiangsu, 210097 P R China
    Zhonghua Yi Xue Yi Chuan Xue Za Zhi 15:206-9. 1998
    ..To detect the parental origin of extra chromosome 21 in Down syndrome, using two (GT)n polymorphic markers-D21S215 and D21S120...