Hui Ling Zhang

Summary

Publications

  1. doi request reprint Neuroprotective effects of pioglitazone in a rat model of permanent focal cerebral ischemia are associated with peroxisome proliferator-activated receptor gamma-mediated suppression of nuclear factor-κB signaling pathway
    H L Zhang
    Department of Pharmacology and Laboratory of Aging and Nervous Diseases, College of Pharmaceutical Science, Soochow University School of Medicine, Suzhou 215123, Jiangsu, PR China
    Neuroscience 176:381-95. 2011
  2. ncbi request reprint Neuroprotective effects of prostaglandin A(1) in rat models of permanent focal cerebral ischemia are associated with nuclear factor-kappaB inhibition and peroxisome proliferator-activated receptor-gamma up-regulation
    Hui Ling Zhang
    Department of Pharmacology and Laboratory of Aging and Nervous Diseases, Soochow University School of Medicine, Suzhou, China
    J Neurosci Res 86:1132-41. 2008
  3. ncbi request reprint Neuroprotective effects of prostaglandin A1 in animal models of focal ischemia
    Hui Ling Zhang
    Department of Pharmacology, Soochow University School of Medicine, 48 Ren Ming Road, Suzhou 215007, PR China
    Brain Res 1039:203-6. 2005
  4. doi request reprint Direct protection of neurons and astrocytes by matrine via inhibition of the NF-κB signaling pathway contributes to neuroprotection against focal cerebral ischemia
    Min Xu
    Department of Pharmacology and Laboratory of Cerebrovascular Pharmacology, College of Pharmaceutical Science, Soochow University, Suzhou 215123, China
    Brain Res 1454:48-64. 2012
  5. ncbi request reprint Inflammatory mechanism in ischemic neuronal injury
    Ya Dan Wen
    Department of Pharmacology, Soochow University, School of Medicine, Suzhou 215123, China E mail
    Neurosci Bull 22:171-82. 2006
  6. ncbi request reprint A short-chain alpha-neurotoxin from Naja naja atra produces potent cholinergic-dependent analgesia
    Hui Ling Zhang
    Department of Pharmacology, Soochow University School of Medicine, Suzhou 215007, China ReceptoPharm, Plantation, Florida, USA E mail
    Neurosci Bull 22:103-9. 2006
  7. doi request reprint Mechanisms of lysosomal proteases participating in cerebral ischemia-induced neuronal death
    Ai Ping Qin
    Department of Pharmacology, Laboratory of Aging and Nervous Disease, Soochow University School of Medicine, Suzhou 215123, China
    Neurosci Bull 24:117-23. 2008
  8. doi request reprint Death and survival of neuronal and astrocytic cells in ischemic brain injury: a role of autophagy
    Min Xu
    Department of Pharmacology and Laboratory of Cerebrovascular Pharmacology, College of Pharmaceutical Science, Soochow University, Suzhou 215123, China
    Acta Pharmacol Sin 32:1089-99. 2011
  9. ncbi request reprint Analgesic effects of receptin, a chemically modified cobratoxin from Thailand cobra venom
    Hui Ling Zhang
    Department of Pharmacology, Soochow University School of Medicine, Suzhou 215123, China ReceptoPharm Inc, Florida 33324, USA E mail
    Neurosci Bull 22:267-73. 2006
  10. doi request reprint p53-mediated neuronal cell death in ischemic brain injury
    Li Zhi Hong
    Department of Pharmacology, Laboratory of Aging and Nervous Diseases, Soochow University School of Medicine, Suzhou 215123, China
    Neurosci Bull 26:232-40. 2010

Collaborators

Detail Information

Publications12

  1. doi request reprint Neuroprotective effects of pioglitazone in a rat model of permanent focal cerebral ischemia are associated with peroxisome proliferator-activated receptor gamma-mediated suppression of nuclear factor-κB signaling pathway
    H L Zhang
    Department of Pharmacology and Laboratory of Aging and Nervous Diseases, College of Pharmaceutical Science, Soochow University School of Medicine, Suzhou 215123, Jiangsu, PR China
    Neuroscience 176:381-95. 2011
    ..The present findings suggest that Piog's neuroprotection appears to be associated with PPARγ-mediated suppression of NF-κB signaling pathway...
  2. ncbi request reprint Neuroprotective effects of prostaglandin A(1) in rat models of permanent focal cerebral ischemia are associated with nuclear factor-kappaB inhibition and peroxisome proliferator-activated receptor-gamma up-regulation
    Hui Ling Zhang
    Department of Pharmacology and Laboratory of Aging and Nervous Diseases, Soochow University School of Medicine, Suzhou, China
    J Neurosci Res 86:1132-41. 2008
    ..These findings suggest that PGA(1)-mediated neuroprotective effect against ischemia appears to be associated with blocking NF-kappaB activation and likely with up-regulating PPAR-gamma expression...
  3. ncbi request reprint Neuroprotective effects of prostaglandin A1 in animal models of focal ischemia
    Hui Ling Zhang
    Department of Pharmacology, Soochow University School of Medicine, 48 Ren Ming Road, Suzhou 215007, PR China
    Brain Res 1039:203-6. 2005
    ..01) when administered immediately following permanent ischemia in rats. PGA1 treatment also significantly ameliorated motor dysfunction after brain ischemia. These results suggest that PGA1 protects neurons from ischemic injury...
  4. doi request reprint Direct protection of neurons and astrocytes by matrine via inhibition of the NF-κB signaling pathway contributes to neuroprotection against focal cerebral ischemia
    Min Xu
    Department of Pharmacology and Laboratory of Cerebrovascular Pharmacology, College of Pharmaceutical Science, Soochow University, Suzhou 215123, China
    Brain Res 1454:48-64. 2012
    ....
  5. ncbi request reprint Inflammatory mechanism in ischemic neuronal injury
    Ya Dan Wen
    Department of Pharmacology, Soochow University, School of Medicine, Suzhou 215123, China E mail
    Neurosci Bull 22:171-82. 2006
    ..While many studies have tested these hypotheses, the significance of inflammation in stroke models is inconclusive. This review summarizes data regarding roles of cell adhesion molecules, astrocytes, microglia and leukocytes in stroke...
  6. ncbi request reprint A short-chain alpha-neurotoxin from Naja naja atra produces potent cholinergic-dependent analgesia
    Hui Ling Zhang
    Department of Pharmacology, Soochow University School of Medicine, Suzhou 215007, China ReceptoPharm, Plantation, Florida, USA E mail
    Neurosci Bull 22:103-9. 2006
    ..The central cholinergic system but not opioid system appears to be involved in the antinociceptive action of CT...
  7. doi request reprint Mechanisms of lysosomal proteases participating in cerebral ischemia-induced neuronal death
    Ai Ping Qin
    Department of Pharmacology, Laboratory of Aging and Nervous Disease, Soochow University School of Medicine, Suzhou 215123, China
    Neurosci Bull 24:117-23. 2008
    ..Moreover, the research related to the selective cathepsin inhibitors may provide a novel therapeutic target for treating stroke and promoting recovery...
  8. doi request reprint Death and survival of neuronal and astrocytic cells in ischemic brain injury: a role of autophagy
    Min Xu
    Department of Pharmacology and Laboratory of Cerebrovascular Pharmacology, College of Pharmaceutical Science, Soochow University, Suzhou 215123, China
    Acta Pharmacol Sin 32:1089-99. 2011
    ....
  9. ncbi request reprint Analgesic effects of receptin, a chemically modified cobratoxin from Thailand cobra venom
    Hui Ling Zhang
    Department of Pharmacology, Soochow University School of Medicine, Suzhou 215123, China ReceptoPharm Inc, Florida 33324, USA E mail
    Neurosci Bull 22:267-73. 2006
    ..The central cholinergic system and opioid peptidergic system appear not to be involved in the antinociceptive action of REC...
  10. doi request reprint p53-mediated neuronal cell death in ischemic brain injury
    Li Zhi Hong
    Department of Pharmacology, Laboratory of Aging and Nervous Diseases, Soochow University School of Medicine, Suzhou 215123, China
    Neurosci Bull 26:232-40. 2010
    ..In this pathway, p53 is translocated to mitochondrial and mediates the release of cytochrome c. In both pathways, p53 seems to play a key role in post-ischemic brain damage and has become a therapeutic target against stroke pathology...
  11. doi request reprint Protective effect of Ginkgolids (A+B) is associated with inhibition of NIK/IKK/IkappaB/NF-kappaB signaling pathway in a rat model of permanent focal cerebral ischemia
    Xuan Wang
    Department of Pharmacology and Laboratory of Aging and Nervous Diseases, Soochow University School of Medicine, Suzhou, China
    Brain Res 1234:8-15. 2008
    ..The present study evaluated the effects of GKAB on NIK/IKK/IkappaB/NF-kappaB signaling pathway in a rat model of permanent focal cerebral ischemia...