Fujie Zhang

Summary

Publications

  1. pmc Mitochondrial toxicity studied with the PBMC of children from the Chinese national pediatric highly active antiretroviral therapy cohort
    Kai Liu
    Department of Medicine, Beijing Youan Hospital, Capital Medical University, Beijing, China Beijing Institute of Hepatology, Beijing, China
    PLoS ONE 8:e57223. 2013
  2. pmc Changing baseline characteristics among patients in the China National Free Antiretroviral Treatment Program, 2002-09
    Zhihui Dou
    Chinese Center for Disease Control and Prevention, Beijing, People s Republic of China
    Int J Epidemiol 39:ii56-64. 2010
  3. doi request reprint Effect of earlier initiation of antiretroviral treatment and increased treatment coverage on HIV-related mortality in China: a national observational cohort study
    Fujie Zhang
    Division of Treatment and Care, National Centre for AIDS STD Control and Prevention, Chinese Centre for Disease Control and Prevention, Beijing, China
    Lancet Infect Dis 11:516-24. 2011
  4. pmc Failure to prescribe pneumocystis prophylaxis is associated with increased mortality, even in the cART era: results from the Treat Asia HIV observational database
    Poh Lian Lim
    Tan Tock Seng Hospital, Singapore
    J Int AIDS Soc 15:1. 2012
  5. pmc Cancers in the TREAT Asia HIV Observational Database (TAHOD): a retrospective analysis of risk factors
    Kathy Petoumenos
    National Centre in HIV Epidemiology and Clinical Research, University of New South Wales, Sydney, NSW, Australia
    J Int AIDS Soc 13:51. 2010
  6. pmc The effect of highly active antiretroviral therapy on mortality among HIV-infected former plasma donors in China
    Fujie Zhang
    National Center for AIDS STD Control and Prevention, Chinese Center for Disease Control and Prevention, Ditan Hospital, Beijing, China
    Clin Infect Dis 47:825-33. 2008
  7. doi request reprint Association between missed early visits and mortality among patients of china national free antiretroviral treatment cohort
    Yao Zhang
    Division of Treatment and Care, National Center for AIDS STD Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing, PR China
    J Acquir Immune Defic Syndr 60:59-67. 2012
  8. pmc Gender difference in 2-year mortality and immunological response to ART in an HIV-infected Chinese population, 2006-2008
    Zhihui Dou
    Chinese Center for Disease Control and Prevention, Beijing, China
    PLoS ONE 6:e22707. 2011
  9. pmc Mortality and treatment outcomes of China's National Pediatric antiretroviral therapy program
    Yan Zhao
    National Center for AIDS STD Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing, PR China
    Clin Infect Dis 56:735-44. 2013
  10. doi request reprint The Chinese free antiretroviral treatment program: challenges and responses
    Fujie Zhang
    National Center for AIDS STD Control and Prevention Chinese Center for Disease Control and Prevention, Beijing, China
    AIDS 21:S143-8. 2007

Collaborators

Detail Information

Publications31

  1. pmc Mitochondrial toxicity studied with the PBMC of children from the Chinese national pediatric highly active antiretroviral therapy cohort
    Kai Liu
    Department of Medicine, Beijing Youan Hospital, Capital Medical University, Beijing, China Beijing Institute of Hepatology, Beijing, China
    PLoS ONE 8:e57223. 2013
    ..These results suggest that mitochondrial toxicity occurs in long-term HAART patients and that P53R2 and TK2 levels in PBMCs are useful biomarkers for detecting mitochondrial toxicity in patients on long-term treatment with NRTIs...
  2. pmc Changing baseline characteristics among patients in the China National Free Antiretroviral Treatment Program, 2002-09
    Zhihui Dou
    Chinese Center for Disease Control and Prevention, Beijing, People s Republic of China
    Int J Epidemiol 39:ii56-64. 2010
    ..To improve HIV treatment in China by determining changes over time of patient characteristics (geographic, clinical and route of HIV infection) among patients enrolled in the China National Free Antiretroviral Treatment Program...
  3. doi request reprint Effect of earlier initiation of antiretroviral treatment and increased treatment coverage on HIV-related mortality in China: a national observational cohort study
    Fujie Zhang
    Division of Treatment and Care, National Centre for AIDS STD Control and Prevention, Chinese Centre for Disease Control and Prevention, Beijing, China
    Lancet Infect Dis 11:516-24. 2011
    ..Overall HIV mortality rates in China have not been reported. In this analysis we assess overall mortality in treatment-eligible adults with HIV and attempt to identify risk factors for HIV-related mortality...
  4. pmc Failure to prescribe pneumocystis prophylaxis is associated with increased mortality, even in the cART era: results from the Treat Asia HIV observational database
    Poh Lian Lim
    Tan Tock Seng Hospital, Singapore
    J Int AIDS Soc 15:1. 2012
    ..This study examines the proportion of patients in the TREAT Asia HIV Observational Database (TAHOD) receiving PCP prophylaxis, and its effect on PCP and mortality...
  5. pmc Cancers in the TREAT Asia HIV Observational Database (TAHOD): a retrospective analysis of risk factors
    Kathy Petoumenos
    National Centre in HIV Epidemiology and Clinical Research, University of New South Wales, Sydney, NSW, Australia
    J Int AIDS Soc 13:51. 2010
    ..This retrospective survey describes types of cancers diagnosed in HIV-infected subjects in Asia, and assesses risk factors for cancer in HIV-infected subjects using contemporaneous HIV-infected controls without cancer...
  6. pmc The effect of highly active antiretroviral therapy on mortality among HIV-infected former plasma donors in China
    Fujie Zhang
    National Center for AIDS STD Control and Prevention, Chinese Center for Disease Control and Prevention, Ditan Hospital, Beijing, China
    Clin Infect Dis 47:825-33. 2008
    ..Highly active antiretroviral therapy (HAART) was provided for former plasma donors beginning in 2002. The effect of HAART on mortality in this cohort has not been described...
  7. doi request reprint Association between missed early visits and mortality among patients of china national free antiretroviral treatment cohort
    Yao Zhang
    Division of Treatment and Care, National Center for AIDS STD Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing, PR China
    J Acquir Immune Defic Syndr 60:59-67. 2012
    ..However, few studies have evaluated indicators for patient access to medical care and their association with mortality...
  8. pmc Gender difference in 2-year mortality and immunological response to ART in an HIV-infected Chinese population, 2006-2008
    Zhihui Dou
    Chinese Center for Disease Control and Prevention, Beijing, China
    PLoS ONE 6:e22707. 2011
    ..Gender differences, however, in mortality and immunological response to ART in this cohort have never been described...
  9. pmc Mortality and treatment outcomes of China's National Pediatric antiretroviral therapy program
    Yan Zhao
    National Center for AIDS STD Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing, PR China
    Clin Infect Dis 56:735-44. 2013
    ..The aim of this study was to describe 3-year mortality rates, associated risk factors, and long-term clinical outcomes of children enrolled in China's national free pediatric antiretroviral therapy (ART) program...
  10. doi request reprint The Chinese free antiretroviral treatment program: challenges and responses
    Fujie Zhang
    National Center for AIDS STD Control and Prevention Chinese Center for Disease Control and Prevention, Beijing, China
    AIDS 21:S143-8. 2007
    ..The Free ART Program has made considerable progress in providing the necessary care and treatment for HIV-infected people in China and has strong government support for continued improvement and expansion...
  11. ncbi request reprint Five-year outcomes of the China National Free Antiretroviral Treatment Program
    Fujie Zhang
    National Center for AIDS STD Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing, China
    Ann Intern Med 151:241-51, W-52. 2009
    ..China's National Free Antiretroviral Treatment Program began in 2002 and, by August 2008, included more than 52 000 patients...
  12. pmc Predictors of virologic failure in HIV-1-infected adults receiving first-line antiretroviral therapy in 8 provinces in China
    Ye Ma
    National Center for AIDS STD Control and Prevention, Chinese Center for Disease Control and Prevention, US Embassy, Beijing, China
    Clin Infect Dis 50:264-71. 2010
    ..Despite poor primary health care systems, free antiretroviral therapy (ART) has been available in China for >5 years. Virologic outcomes in Chinese patients receiving ART have not been described on a national level...
  13. doi request reprint Monitoring HIV drug resistance using early warning indicators in China: results from a pilot survey conducted in 2008
    Ye Ma
    Division of Treatment and Care, National Center for AIDS STD Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing, China
    Clin Infect Dis 54:S300-2. 2012
    ..HIV drug resistance early warning indicator monitoring provides a valuable assessment of ART service delivery, and its application will be scaled up throughout China...
  14. ncbi request reprint Incidence and associated factors of pulmonary tuberculosis in HIV-infected children after highly active antiretroviral therapy (HAART) in China: a retrospective study
    Weiwei Mu
    a Division of Treatment and Care, National Center for AIDS STD Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing, China
    AIDS Care 26:1127-35. 2014
    ..Late clinical stage at ART initiation was shown to relate with TB incidence. PTB coinfection leads to higher mortality. Early diagnosis and treatment of HIV are highly required to reduce HIV-associated morbidity and mortality due to TB. ..
  15. doi request reprint Excessive conversion and impaired thymic output contribute to disturbed regulatory T-cell homeostasis in AIDS patients with low CD4 cell counts
    Haiwei Zhou
    Beijing Key Laboratory of Emerging Infectious Diseases, Institute of Infectious Diseases, Beijing Ditan Hospital, Capital Medical University, Beijing, China
    AIDS 27:1059-69. 2013
    ..We investigated the effects of HIV infection and HAART on distinct Treg subsets...
  16. ncbi request reprint CD14(high)CD16(+) rather than CD14(low)CD16(+) monocytes correlate with disease progression in chronic HIV-infected patients
    Junyan Han
    Institute of Infectious Diseases, Capital Medical University, Beijing, China
    J Acquir Immune Defic Syndr 52:553-9. 2009
    ..Because CD14(+)CD16(+) monocytes are a heterogeneous population and consist of CD14(high)CD16(+) and CD14(low)CD16(+) subsets, we evaluated the effects of HIV infection on distinct subsets of CD16(+) monocytes...
  17. doi request reprint Progress of the National Pediatric Free Antiretroviral Therapy program in China
    Yan Zhao
    National Center for AIDS STD Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing, Xuan Wu District, China
    AIDS Care 22:1182-8. 2010
    ..Secondly, much of the pediatric ARV drug supply depends on donation. An effort needs to be made by the Chinese Government to establish China's own drug procurement and supply system...
  18. pmc Hepatitis B and hepatitis C seroprevalence in children receiving antiretroviral therapy for human immunodeficiency virus-1 infection in China, 2005-2009
    Shuntai Zhou
    Division of Treatment and Care, National Center for AIDS STI Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing, China
    J Acquir Immune Defic Syndr 54:191-6. 2010
    ..In this study, we evaluated the seroprevalence of HBV and HCV in children receiving ART and associated factors...
  19. pmc Methadone maintenance treatment and mortality in HIV-positive people who inject opioids in China
    Yan Zhao
    National Center for AIDS STD Control and Prevention, Chinese Center for Disease Control and Prevention, 155 Changbai Road, Changping District, Beijing, 102206, China
    Bull World Health Organ 91:93-101. 2013
    ..To examine the effect of methadone maintenance treatment (MMT) on mortality in people injecting opioids who receive antiretroviral therapy (ART) for the treatment of human immunodeficiency virus (HIV) infection in China...
  20. pmc Decreasing excess mortality of HIV-infected patients initiating antiretroviral therapy: comparison with mortality in general population in China, 2003-2009
    Hao Zhu
    Department of Epidemiology, Gillings School of Global Public Health, University of North Carolina, Chapel Hill, NC Division of Treatment and Care, National Center for AIDS STD Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing, China Division of Infectious Diseases, School of Medicine, University of North Carolina, Chapel Hill, NC and Division of Infectious Diseases, Beijing Ditan Hospital Capital Medical University, Beijing, China
    J Acquir Immune Defic Syndr 63:e150-7. 2013
    ..To evaluate excess mortality across calendar time comparing HIV-infected patients receiving combination antiretroviral therapy (cART) with the general Chinese population...
  21. doi request reprint Antiretroviral therapy to prevent HIV transmission in serodiscordant couples in China (2003-11): a national observational cohort study
    Zhongwei Jia
    National Institute of Drug Dependence, Peking University, Beijing, China
    Lancet 382:1195-203. 2013
    ..Whether or not such a public health approach is feasible and the outcomes are sustainable at a large scale and in a developing country setting has not previously been assessed...
  22. pmc HIV-infected former plasma donors in rural Central China: from infection to survival outcomes, 1985-2008
    Zhihui Dou
    Chinese Center for Disease Control and Prevention, Beijing, China
    PLoS ONE 5:e13737. 2010
    ..The objectives of this study are to estimate the timing and geographic spread of HIV infection in this cohort and to demonstrate the impact of antiretroviral therapy on survival outcomes...
  23. ncbi request reprint The diagnosis and treatment of HIV-infected children in China: challenges and opportunities
    Fujie Zhang
    National Center for AIDS STD Control and Prevention, Chinese Center for Disease Control, Beijing, People s Republic of China
    J Acquir Immune Defic Syndr 44:429-34. 2007
    ..This national survey describes the demographic characteristics and the associated diagnostic and antiretroviral treatment (ART) efforts directed toward surviving HIV-infected children...
  24. pmc Quantitatively monitoring AIDS policy implementation in China
    Yufen Liu
    Chinese Center for Disease Control and Prevention, Beijing, China
    Int J Epidemiol 39:ii90-6. 2010
    ..We tested a hypothesis that incrementally setting realistic quantitative targets for key indicators and monitoring performance would facilitate AIDS policy implementation in China...
  25. pmc Estimating the number of people living with HIV/AIDS in China: 2003-09
    Ning Wang
    Chinese Center for Disease Control and Prevention, Beijing, China
    Int J Epidemiol 39:ii21-8. 2010
    ..Subsequent national estimation exercises were carried out in 2005, 2007 and 2009. We describe these estimation processes and present the results of China's HIV/AIDS estimation exercises from 2003 to 2009...
  26. ncbi request reprint Chinese pediatric highly active antiretroviral therapy observational cohort: a 1-year analysis of clinical, immunologic, and virologic outcomes
    Fujie Zhang
    Chinese Center for Disease Control and Prevention, National Center for AIDS, Division of Treatment and Care, Beijing, China
    J Acquir Immune Defic Syndr 46:594-8. 2007
    ..Few data are available on the outcomes of pediatric antiretroviral therapy (ART) in the developing world...
  27. doi request reprint Drug resistance profiles among HIV-1-infected children experiencing delayed switch and 12-month efficacy after using second-line antiretroviral therapy: an observational cohort study in rural China
    Yan Zhao
    Division of Treatment and Care, National Center for AIDS STD Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing, China
    J Acquir Immune Defic Syndr 58:47-53. 2011
    ....
  28. pmc Transovarial transmission of a plant virus is mediated by vitellogenin of its insect vector
    Yan Huo
    State Key Laboratory of Plant Genomics, Institute of Microbiology, Chinese Academy of Sciences, Beijing, China National Plant Gene Research Center, Beijing, China Graduate School of the Chinese Academy of Sciences, Beijing, China
    PLoS Pathog 10:e1003949. 2014
    ..Our results show that the Vg of L. striatellus played a critical role in transovarial transmission of RSV and shows how viruses can use existing transovarial transportation systems in insect vectors for their own purposes. ..
  29. doi request reprint Rice yellow stunt rhabdovirus protein 6 suppresses systemic RNA silencing by blocking RDR6-mediated secondary siRNA synthesis
    Hongyan Guo
    Chinese Academy of Sciences, Beijing, China
    Mol Plant Microbe Interact 26:927-36. 2013
    ..Our work provides a new perspective on how a plant-infecting nucleorhabdovirus may counteract host RNA silencing-mediated antiviral defense. ..
  30. pmc Massively parallel pyrosequencing-based transcriptome analyses of small brown planthopper (Laodelphax striatellus), a vector insect transmitting rice stripe virus (RSV)
    Fujie Zhang
    State Key Laboratory of Plant Genomics, Institute of Microbiology, Chinese Academy of Sciences, Beijing, China
    BMC Genomics 11:303. 2010
    ..To investigate its transcriptome and determine the differences between viruliferous and naïve L. striatellus, we employed 454-FLX high-throughput pyrosequencing to generate EST databases of this insect...
  31. doi request reprint Therapeutic drug monitoring in highly active antiretroviral therapy
    Xia Liu
    National Center for AIDS STD Control and Prevention, Chinese Center for Disease Control and Prevention, 27 Nan Wei Road, Beijing 100050, China
    Expert Opin Drug Saf 9:743-58. 2010
    ..Therapeutic drug monitoring (TDM) has been utilised to improve treatment outcomes of ART...