Tarek Zghoul

Summary

Publications

  1. ncbi request reprint The clock gene Per2 influences the glutamatergic system and modulates alcohol consumption
    Rainer Spanagel
    Department of Psychopharmacology, Central Institute of Mental Health, J5, 68159 Mannheim, Germany
    Nat Med 11:35-42. 2005
  2. ncbi request reprint Ethanol self-administration and reinstatement of ethanol-seeking behavior in Per1(Brdm1) mutant mice
    Tarek Zghoul
    Department of Psychopharmacology, Central Institute of Mental Health, University of Heidelberg, J5, 68159, Mannheim, Germany
    Psychopharmacology (Berl) 190:13-9. 2007
  3. doi request reprint Circadian regulation of central ethanol sensitivity by the mPer2 gene
    Stephanie Perreau-Lenz
    Department of Psychopharmacology, Central Institute of Mental Health, University of Heidelberg, J5, Mannheim, Germany
    Addict Biol 14:253-9. 2009
  4. ncbi request reprint Involvement of the AMPA receptor GluR-C subunit in alcohol-seeking behavior and relapse
    Carles Sanchis-Segura
    Department of Psychopharmacology, Central Institute of Mental Health, University of Heidelberg, 68072 Mannheim, Germany
    J Neurosci 26:1231-8. 2006
  5. pmc Clock genes running amok. Clock genes and their role in drug addiction and depression
    Stephanie Perreau-Lenz
    Department of Psychopharmacology, Central Institute of Mental Health, Mannheim, Germany
    EMBO Rep 8:S20-3. 2007

Detail Information

Publications5

  1. ncbi request reprint The clock gene Per2 influences the glutamatergic system and modulates alcohol consumption
    Rainer Spanagel
    Department of Psychopharmacology, Central Institute of Mental Health, J5, 68159 Mannheim, Germany
    Nat Med 11:35-42. 2005
    ..Collectively, these data establish glutamate as a link between dysfunction of the circadian clock gene Per2 and enhanced alcohol intake...
  2. ncbi request reprint Ethanol self-administration and reinstatement of ethanol-seeking behavior in Per1(Brdm1) mutant mice
    Tarek Zghoul
    Department of Psychopharmacology, Central Institute of Mental Health, University of Heidelberg, J5, 68159, Mannheim, Germany
    Psychopharmacology (Berl) 190:13-9. 2007
    ..Objective To further complement the mPer2 study, our lab proceeded to assess mPer1's possible role on alcohol intake using operant and free choice two bottle paradigms...
  3. doi request reprint Circadian regulation of central ethanol sensitivity by the mPer2 gene
    Stephanie Perreau-Lenz
    Department of Psychopharmacology, Central Institute of Mental Health, University of Heidelberg, J5, Mannheim, Germany
    Addict Biol 14:253-9. 2009
    ..The present study reveals a central role of the mPer2 gene in inhibiting alcohol sensitivity at the beginning of the inactive phase...
  4. ncbi request reprint Involvement of the AMPA receptor GluR-C subunit in alcohol-seeking behavior and relapse
    Carles Sanchis-Segura
    Department of Psychopharmacology, Central Institute of Mental Health, University of Heidelberg, 68072 Mannheim, Germany
    J Neurosci 26:1231-8. 2006
    ..In conclusion, AMPA receptors seem to be involved in the neuroplastic changes underlying alcohol seeking behavior and relapse. Thus, AMPA receptors represent a novel therapeutic target in preventing relapse...
  5. pmc Clock genes running amok. Clock genes and their role in drug addiction and depression
    Stephanie Perreau-Lenz
    Department of Psychopharmacology, Central Institute of Mental Health, Mannheim, Germany
    EMBO Rep 8:S20-3. 2007