Role of calcium and dairy products in energy partitioning and weight managementMichael B Zemel
University of Tennessee Nutrition Institute, 1215 West Cumberland Avenue, Room 229, Knoxville, TN 37996 1920, USA
Am J Clin Nutr 79:907S-912S. 2004
..These data indicate an important role for dairy products in both the prevention and treatment of obesity...
- Calcium and dairy products inhibit weight and fat regain during ad libitum consumption following energy restriction in Ap2-agouti transgenic mice
Xiaocun Sun
Department of Nutrition, University of Tennessee, Knoxville, TN 37996, USA
J Nutr 134:3054-60. 2004
..01). Thus, high-Ca diets elicit a shift in energy partitioning and reduction of weight gain during refeeding, with dairy Ca sources exerting markedly greater effects...
- Effect of dietary carbohydrate source on the development of obesity in agouti transgenic mice
Kristin L Morris
Department of Nutrition, University of Tennessee, Room 229 Jessie Harris Building, 1215 West Cumberland Avenue, Knoxville, TN 37996, USA
Obes Res 13:21-35. 2005
..05) with ROLL and MUNG diets compared with all others. DISCUSSION: These data suggest that a qualitative change in dietary carbohydrate source modulates body weight and adiposity...
- Effects of calcium and dairy on body composition and weight loss in African-American adults
Michael B Zemel
Department of Nutrition, The University of Tennessee, 1215 W Cumberland Avenue, Room 229, Knoxville, TN 37996 1920, USA
Obes Res 13:1218-25. 2005
..Our objective was to determine the effects of dairy consumption on adiposity and body composition in obese African Americans...
- 1Alpha,25-dihydroxyvitamin D3 modulation of adipocyte reactive oxygen species production
Xiaocun Sun
Department of Nutrition, University of Tennessee, 1215 West Cumberland Avenue, 229, Knoxville, TN 37996 1900, USA
Obesity (Silver Spring) 15:1944-53. 2007
..Because UCP2 plays a significant role in the clearance of reactive oxygen species (ROS), we studied the effect of calcitriol on ROS production and ROS-induced adipocyte proliferation...
- Leucine and calcium regulate fat metabolism and energy partitioning in murine adipocytes and muscle cells
Xiaocun Sun
Department of Nutrition, University of Tennessee, 1215 W Cumberland Avenue, Knoxville, TN 37996 1920, USA
Lipids 42:297-305. 2007
..These data suggest that leucine and nifedipine promote energy partitioning from adipocytes to muscle cells, resulting in decreased energy storage in adipocytes and increasing fatty acid utilization in muscle...
Effects of a leucine and pyridoxine-containing nutraceutical on fat oxidation, and oxidative and inflammatory stress in overweight and obese subjectsMichael B Zemel
NuSirt Sciences, Knoxville, TN 37931, USA
Nutrients 4:529-41. 2012
..Therefore, the NuFit active blend appears to be a useful nutraceutical in the management of obesity and associated co-morbidities...
Calcitriol and energy metabolismMichael B Zemel
the Department of Nutrition, The University of Tennessee, Knoxville, Tennessee 37996 1920, USA
Nutr Rev 66:S139-46. 2008
..Recent data also demonstrate a pivotal role of calcitriol in the modulation of cytokines, with potential roles in energy metabolism in adipocytes, macrophages, and skeletal muscle...
- The role of dairy foods in weight management
Michael B Zemel
The University of Tennessee, 1215 W Cumberland Ave, Room 229, Knoxville, TN 37996 1920, USA
J Am Coll Nutr 24:537S-46S. 2005
..These data indicate an important role for dairy products in both the ability to maintain a healthy weight and the management of overweight and obesity...
- The effects of dairy components on energy partitioning and metabolic risk in mice: a microarray study
Antje Bruckbauer
Department of Nutrition, University of Tennessee, Knoxville, Tenn, USA
J Nutrigenet Nutrigenomics 2:64-77. 2009
....
- Dairy-rich diets augment fat loss on an energy-restricted diet: a multicenter trial
Michael B Zemel
The University of Tennessee, Knoxville, TN 37996, USA
Nutrients 1:83-100. 2009
..025). Similar effects were noted among all subjects completing the study and in an intent-to-treat analysis. These data indicate that dairy-rich diets augment weight loss by targeting the fat compartment during energy restriction...
- Calcium and 1,25-dihydroxyvitamin D3 regulation of adipokine expression
Xiaocun Sun
Department of Nutrition, University of Tennessee, Knoxville, TN 37996 1900, USA
Obesity (Silver Spring) 15:340-8. 2007
..However, whether the anti-obesity effect of dietary calcium plays a role in regulation of obesity-associated inflammation is not clear...
- Proposed role of calcium and dairy food components in weight management and metabolic health
Michael B Zemel
The Nutrition Institute, The University of Tennessee, Knoxville, TN 37996 1920, USA
Phys Sportsmed 37:29-39. 2009
..Thus, the protective effects of dairy foods against obesity and its comorbidities are promising, but warrant further large-scale studies...
- Role of uncoupling protein 2 (UCP2) expression and 1alpha, 25-dihydroxyvitamin D3 in modulating adipocyte apoptosis
Xiaocun Sun
Department of Nutrition, University of Tennessee, Knoxville, TN 37996-1900, USA
FASEB J 18:1430-2. 2004
..01), suggesting that increasing dietary calcium stimulates adipose apoptosis and thereby further contributes to an anti-obesity effect of dietary calcium...
- Dietary calcium and dairy modulation of adiposity and obesity risk
Michael B Zemel
Department of Nutrition, University of Tennessee, Knoxville, TN 37996-1920, USA
Nutr Rev 62:125-31. 2004
..Moreover, dairy sources of calcium exert markedly greater effects which are most likely attributable to additional bioactive compounds in dairy which act synergistically with calcium to attenuate adiposity...
- Role of calcitriol and cortisol on human adipocyte proliferation and oxidative and inflammatory stress: a microarray study
Xiaocun Sun
University of Tennessee, Knoxville, Tenn 37996 1900, USA
J Nutrigenet Nutrigenomics 1:30-48. 2008
....
- Dietary calcium and dairy products modulate oxidative and inflammatory stress in mice and humans
Michael B Zemel
Department of Nutrition, University of Tennessee, Knoxville, TN 37996, USA
J Nutr 138:1047-52. 2008
..003) and 18% in those fed the hypocaloric high-dairy diet (P < 0.05). These data demonstrate that dietary Ca suppresses adipose tissue oxidative and inflammatory stress...
- Effects of dairy compared with soy on oxidative and inflammatory stress in overweight and obese subjects
Michael B Zemel
Department of Nutrition, The University of Tennessee, Knoxville, TN 37996 1920, USA
Am J Clin Nutr 91:16-22. 2010
..However, these findings may be confounded by concomitant changes in adiposity...
- Dietary calcium and dairy modulation of oxidative stress and mortality in aP2-agouti and wild-type mice
Antje Bruckbauer
Department of Nutrition, The University of Tennessee, Knoxville, TN 37996 1920, USA
Nutrients 1:50-70. 2009
..Although these effects did not alter maximum lifespan, they did suppress early mortality in wild-type mice, but not in aP2-agouti transgenic mice...
- 1,25-dihydroxyvitamin D3 modulation of adipocyte glucocorticoid function
Kristin L Morris
Department of Nutrition, University of Tennessee, Room 229, Jessie Harris Building, 1215 West Cumberland Avenue, Knoxville, TN 37996, USA
Obes Res 13:670-7. 2005
....
- Calcium and dairy acceleration of weight and fat loss during energy restriction in obese adults
Michael B Zemel
University of Tennessee, Knoxville, Tennessee 37996 1920, USA
Obes Res 12:582-90. 2004
..Our objective was to determine the effects of increasing dietary calcium in the face of caloric restriction in humans...
- Role of dietary calcium and dairy products in modulating adiposity
Michael B Zemel
Department of Nutrition, The University of Tennessee, Nutrition Institute, Knoxville, Tennessee 37996, USA
Lipids 38:139-46. 2003
..These data indicate an important role for dairy products in both the prevention and treatment of obesity...
- Calcitriol and calcium regulate cytokine production and adipocyte-macrophage cross-talk
Xiaocun Sun
Department of Nutrition, University of Tennessee, Knoxville, TN 37996 1900, USA
J Nutr Biochem 19:392-9. 2008
..These data provide further mechanistic explanation for our recent observations that suppression of calcitriol by dietary calcium reduces inflammatory cytokine expression and oxidative stress in adipose tissue...
- Dairy attentuates oxidative and inflammatory stress in metabolic syndrome
Renée A Stancliffe
Department of Nutrition, The University of Tennessee, Knoxville, TN 37996 1920, USA
Am J Clin Nutr 94:422-30. 2011
..We showed previously that dairy components suppress the adipocyte- and macrophage-mediated generation of reactive oxygen species and inflammatory cytokines and systemic oxidative and inflammatory biomarkers in obesity...
- Effects of mitochondrial uncoupling on adipocyte intracellular Ca(2+) and lipid metabolism
Xiaocun Sun
University of Tennessee, Knoxville, TN 37996, USA
J Nutr Biochem 14:219-26. 2003
....
- Synergistic effects of leucine and resveratrol on insulin sensitivity and fat metabolism in adipocytes and mice
Antje Bruckbauer
NuSirt Sciences Inc, 11020 Solway School Rd, Knoxville, TN, 37931, USA
Nutr Metab (Lond) 9:77. 2012
..abstract:..
- Effects of dietary carbohydrate on the development of obesity in heterozygous Zucker rats
Kristin L Morris
Department of Nutrition, The University of Tennessee, Knoxville, TN 37996, USA
J Nutr Biochem 14:32-9. 2003
..Therefore, diets that contain minimal carbohydrate may minimize net lipid storage and adiposity...
- Effects of dairy intake on weight maintenance
Michael B Zemel
The University of Tennessee, Knoxville, TN, USA
Nutr Metab (Lond) 5:28. 2008
..To compare the effects of low versus recommended levels of dairy intake on weight maintenance and body composition subsequent to weight loss...
- Effects of dairy consumption on SIRT1 and mitochondrial biogenesis in adipocytes and muscle cells
Antje Bruckbauer
Department of Nutrition, University of Tennessee, Knoxville, TN, USA
Nutr Metab (Lond) 8:91. 2011
..abstract:..
- Leucine modulation of mitochondrial mass and oxygen consumption in skeletal muscle cells and adipocytes
Xiaocun Sun
University of Tennessee, Knoxville, Tennessee, 37996, USA
Nutr Metab (Lond) 6:26. 2009
..abstract:..
- Prostaglandin E(2) protects intestinal tumors from nonsteroidal anti-inflammatory drug-induced regression in Apc(Min/+) mice
Melissa B Hansen-Petrik
Department of Nutrition, University of Tennessee, Knoxville, Tennessee 37996, USA
Cancer Res 62:403-8. 2002
..Overall, our results suggest that NSAIDs exert their antitumorigenic effects, in part, via interference with PGE(2) biosynthesis, and these effects may be mediated through changes in intracellular calcium levels...
- 1alpha,25-dihydroxyvitamin D3 inhibits uncoupling protein 2 expression in human adipocytes
Hang Shi
University of Tennessee, Knoxville, Tennessee 37996, USA
FASEB J 16:1808-10. 2002
..Thus, suppression of 1alpha,25-(OH)2-D3 and consequent up-regulation of UCP2 may contribute to our previous observation of increased thermogenesis in mice fed with high calcium diets...
- Calcium and dairy product modulation of lipid utilization and energy expenditure
Dorothy Teegarden
Interdepartmental Nutrition Program, Purdue University, West Lafayette, Indiana, USA
Obesity (Silver Spring) 16:1566-72. 2008
..The purpose of this study was to investigate the impact of dietary calcium or dairy product intake on total energy expenditure (TEE), fat oxidation, and thermic effect of a meal (TEM) during a weight loss trial...
- Regulation of adiposity and obesity risk by dietary calcium: mechanisms and implications
Michael B Zemel
The University of Tennessee, Knoxville 37996, USA
J Am Coll Nutr 21:146S-151S. 2002
....
- Mechanisms of dairy modulation of adiposity
Michael B Zemel
Department of Nutrition, The University of Tennessee, Knoxville 37996, USA
J Nutr 133:252S-256S. 2003
....
- Calcium and dairy modulation of obesity risk
Michael B Zemel
Obes Res 13:192-3. 2005
- Effect of energy-reduced diets high in dairy products and fiber on weight loss in obese adults
Warren G Thompson
Mayo Clinic Graduate School of Medicine, Division of Preventive and Occupational Medicine, Rochester, MN 55905, USA
Obes Res 13:1344-53. 2005
..The effects on weight loss and body fat of a high-dairy diet and a diet high in dairy and fiber and low in glycemic index were compared with a standard diet...
- Effect of low- and high-calcium dairy-based diets on macronutrient oxidation in humans
Edward L Melanson
Center for Human Nutrition, University of Colorado Health Sciences Center, Denver, 80262, USA
Obes Res 13:2102-12. 2005
..Higher calcium and dairy intakes may be associated with lower body weights, but a mechanism in humans has yet to be elucidated. We compared the effects of a dairy-based high-calcium diet and a low-calcium diet on macronutrient oxidation...
- Functional properties of whey, whey components, and essential amino acids: mechanisms underlying health benefits for active people (review)
Ewan Ha
Functional Ingredients Research, Inc, Twin Falls, Idaho, USA
J Nutr Biochem 14:251-8. 2003
..From a mechanistic standpoint, whey proteins, their composite amino acids, and/or associated compounds may be able to provide substrate and bioactive components to extend the overall benefits of physical activity...
- Dairy product components and weight regulation: symposium overview
Dorothy Teegarden
Purdue University, West Lafayette, IN, USA
J Nutr 133:243S-244S. 2003
