Michael B Zemel

Summary

Publications

  1. ncbi Calcium and dairy acceleration of weight and fat loss during energy restriction in obese adults
    Michael B Zemel
    University of Tennessee, Knoxville, Tennessee 37996 1920, USA
    Obes Res 12:582-90. 2004
  2. ncbi Effects of calcium and dairy on body composition and weight loss in African-American adults
    Michael B Zemel
    Department of Nutrition, The University of Tennessee, 1215 W Cumberland Avenue, Room 229, Knoxville, TN 37996 1920, USA
    Obes Res 13:1218-25. 2005
  3. ncbi Calcium and dairy products inhibit weight and fat regain during ad libitum consumption following energy restriction in Ap2-agouti transgenic mice
    Xiaocun Sun
    Department of Nutrition, University of Tennessee, Knoxville, TN 37996, USA
    J Nutr 134:3054-60. 2004
  4. ncbi Effect of dietary carbohydrate source on the development of obesity in agouti transgenic mice
    Kristin L Morris
    Department of Nutrition, University of Tennessee, Room 229 Jessie Harris Building, 1215 West Cumberland Avenue, Knoxville, TN 37996, USA
    Obes Res 13:21-35. 2005
  5. ncbi 1Alpha,25-dihydroxyvitamin D3 modulation of adipocyte reactive oxygen species production
    Xiaocun Sun
    Department of Nutrition, University of Tennessee, 1215 West Cumberland Avenue, 229, Knoxville, TN 37996 1900, USA
    Obesity (Silver Spring) 15:1944-53. 2007
  6. ncbi Leucine and calcium regulate fat metabolism and energy partitioning in murine adipocytes and muscle cells
    Xiaocun Sun
    Department of Nutrition, University of Tennessee, 1215 W Cumberland Avenue, Knoxville, TN 37996 1920, USA
    Lipids 42:297-305. 2007
  7. pmc Effects of a leucine and pyridoxine-containing nutraceutical on fat oxidation, and oxidative and inflammatory stress in overweight and obese subjects
    Michael B Zemel
    NuSirt Sciences, Knoxville, TN 37931, USA
    Nutrients 4:529-41. 2012
  8. doi The effects of dairy components on energy partitioning and metabolic risk in mice: a microarray study
    Antje Bruckbauer
    Department of Nutrition, University of Tennessee, Knoxville, Tenn, USA
    J Nutrigenet Nutrigenomics 2:64-77. 2009
  9. ncbi The role of dairy foods in weight management
    Michael B Zemel
    The University of Tennessee, 1215 W Cumberland Ave, Room 229, Knoxville, TN 37996 1920, USA
    J Am Coll Nutr 24:537S-46S. 2005
  10. ncbi Role of calcium and dairy products in energy partitioning and weight management
    Michael B Zemel
    University of Tennessee Nutrition Institute, 1215 West Cumberland Avenue, Room 229, Knoxville, TN 37996 1920, USA
    Am J Clin Nutr 79:907S-912S. 2004

Detail Information

Publications40

  1. ncbi Calcium and dairy acceleration of weight and fat loss during energy restriction in obese adults
    Michael B Zemel
    University of Tennessee, Knoxville, Tennessee 37996 1920, USA
    Obes Res 12:582-90. 2004
    ..Our objective was to determine the effects of increasing dietary calcium in the face of caloric restriction in humans...
  2. ncbi Effects of calcium and dairy on body composition and weight loss in African-American adults
    Michael B Zemel
    Department of Nutrition, The University of Tennessee, 1215 W Cumberland Avenue, Room 229, Knoxville, TN 37996 1920, USA
    Obes Res 13:1218-25. 2005
    ..Our objective was to determine the effects of dairy consumption on adiposity and body composition in obese African Americans...
  3. ncbi Calcium and dairy products inhibit weight and fat regain during ad libitum consumption following energy restriction in Ap2-agouti transgenic mice
    Xiaocun Sun
    Department of Nutrition, University of Tennessee, Knoxville, TN 37996, USA
    J Nutr 134:3054-60. 2004
    ..01). Thus, high-Ca diets elicit a shift in energy partitioning and reduction of weight gain during refeeding, with dairy Ca sources exerting markedly greater effects...
  4. ncbi Effect of dietary carbohydrate source on the development of obesity in agouti transgenic mice
    Kristin L Morris
    Department of Nutrition, University of Tennessee, Room 229 Jessie Harris Building, 1215 West Cumberland Avenue, Knoxville, TN 37996, USA
    Obes Res 13:21-35. 2005
    ..Our objective was to evaluate the effects of a qualitative change in dietary carbohydrate source on body weight and adiposity in a rodent model of diet-induced obesity...
  5. ncbi 1Alpha,25-dihydroxyvitamin D3 modulation of adipocyte reactive oxygen species production
    Xiaocun Sun
    Department of Nutrition, University of Tennessee, 1215 West Cumberland Avenue, 229, Knoxville, TN 37996 1900, USA
    Obesity (Silver Spring) 15:1944-53. 2007
    ..Because UCP2 plays a significant role in the clearance of reactive oxygen species (ROS), we studied the effect of calcitriol on ROS production and ROS-induced adipocyte proliferation...
  6. ncbi Leucine and calcium regulate fat metabolism and energy partitioning in murine adipocytes and muscle cells
    Xiaocun Sun
    Department of Nutrition, University of Tennessee, 1215 W Cumberland Avenue, Knoxville, TN 37996 1920, USA
    Lipids 42:297-305. 2007
    ..These data suggest that leucine and nifedipine promote energy partitioning from adipocytes to muscle cells, resulting in decreased energy storage in adipocytes and increasing fatty acid utilization in muscle...
  7. pmc Effects of a leucine and pyridoxine-containing nutraceutical on fat oxidation, and oxidative and inflammatory stress in overweight and obese subjects
    Michael B Zemel
    NuSirt Sciences, Knoxville, TN 37931, USA
    Nutrients 4:529-41. 2012
    ..Therefore, the NuFit active blend appears to be a useful nutraceutical in the management of obesity and associated co-morbidities...
  8. doi The effects of dairy components on energy partitioning and metabolic risk in mice: a microarray study
    Antje Bruckbauer
    Department of Nutrition, University of Tennessee, Knoxville, Tenn, USA
    J Nutrigenet Nutrigenomics 2:64-77. 2009
    ....
  9. ncbi The role of dairy foods in weight management
    Michael B Zemel
    The University of Tennessee, 1215 W Cumberland Ave, Room 229, Knoxville, TN 37996 1920, USA
    J Am Coll Nutr 24:537S-46S. 2005
    ..These data indicate an important role for dairy products in both the ability to maintain a healthy weight and the management of overweight and obesity...
  10. ncbi Role of calcium and dairy products in energy partitioning and weight management
    Michael B Zemel
    University of Tennessee Nutrition Institute, 1215 West Cumberland Avenue, Room 229, Knoxville, TN 37996 1920, USA
    Am J Clin Nutr 79:907S-912S. 2004
    ..These data indicate an important role for dairy products in both the prevention and treatment of obesity...
  11. doi Calcitriol and energy metabolism
    Michael B Zemel
    the Department of Nutrition, The University of Tennessee, Knoxville, Tennessee 37996 1920, USA
    Nutr Rev 66:S139-46. 2008
    ..Recent data also demonstrate a pivotal role of calcitriol in the modulation of cytokines, with potential roles in energy metabolism in adipocytes, macrophages, and skeletal muscle...
  12. pmc Dairy-rich diets augment fat loss on an energy-restricted diet: a multicenter trial
    Michael B Zemel
    The University of Tennessee, Knoxville, TN 37996, USA
    Nutrients 1:83-100. 2009
    ..025). Similar effects were noted among all subjects completing the study and in an intent-to-treat analysis. These data indicate that dairy-rich diets augment weight loss by targeting the fat compartment during energy restriction...
  13. doi Proposed role of calcium and dairy food components in weight management and metabolic health
    Michael B Zemel
    The Nutrition Institute, The University of Tennessee, Knoxville, TN 37996 1920, USA
    Phys Sportsmed 37:29-39. 2009
    ..Thus, the protective effects of dairy foods against obesity and its comorbidities are promising, but warrant further large-scale studies...
  14. ncbi Role of uncoupling protein 2 (UCP2) expression and 1alpha, 25-dihydroxyvitamin D3 in modulating adipocyte apoptosis
    Xiaocun Sun
    Department of Nutrition, University of Tennessee, Knoxville, TN 37996 1900, USA
    FASEB J 18:1430-2. 2004
    ..01), suggesting that increasing dietary calcium stimulates adipose apoptosis and thereby further contributes to an anti-obesity effect of dietary calcium...
  15. ncbi Calcium and 1,25-dihydroxyvitamin D3 regulation of adipokine expression
    Xiaocun Sun
    Department of Nutrition, University of Tennessee, Knoxville, TN 37996 1900, USA
    Obesity (Silver Spring) 15:340-8. 2007
    ..However, whether the anti-obesity effect of dietary calcium plays a role in regulation of obesity-associated inflammation is not clear...
  16. doi Effects of dairy compared with soy on oxidative and inflammatory stress in overweight and obese subjects
    Michael B Zemel
    Department of Nutrition, The University of Tennessee, Knoxville, TN 37996 1920, USA
    Am J Clin Nutr 91:16-22. 2010
    ..However, these findings may be confounded by concomitant changes in adiposity...
  17. ncbi Dietary calcium and dairy modulation of adiposity and obesity risk
    Michael B Zemel
    Department of Nutrition, University of Tennessee, Knoxville, TN 37996 1920, USA
    Nutr Rev 62:125-31. 2004
    ..Moreover, dairy sources of calcium exert markedly greater effects which are most likely attributable to additional bioactive compounds in dairy which act synergistically with calcium to attenuate adiposity...
  18. ncbi Dietary calcium and dairy products modulate oxidative and inflammatory stress in mice and humans
    Michael B Zemel
    Department of Nutrition, University of Tennessee, Knoxville, TN 37996, USA
    J Nutr 138:1047-52. 2008
    ..003) and 18% in those fed the hypocaloric high-dairy diet (P < 0.05). These data demonstrate that dietary Ca suppresses adipose tissue oxidative and inflammatory stress...
  19. doi Role of calcitriol and cortisol on human adipocyte proliferation and oxidative and inflammatory stress: a microarray study
    Xiaocun Sun
    University of Tennessee, Knoxville, Tenn 37996 1900, USA
    J Nutrigenet Nutrigenomics 1:30-48. 2008
    ....
  20. pmc Dietary calcium and dairy modulation of oxidative stress and mortality in aP2-agouti and wild-type mice
    Antje Bruckbauer
    Department of Nutrition, The University of Tennessee, Knoxville, TN 37996 1920, USA
    Nutrients 1:50-70. 2009
    ..Although these effects did not alter maximum lifespan, they did suppress early mortality in wild-type mice, but not in aP2-agouti transgenic mice...
  21. ncbi 1,25-dihydroxyvitamin D3 modulation of adipocyte glucocorticoid function
    Kristin L Morris
    Department of Nutrition, University of Tennessee, Room 229, Jessie Harris Building, 1215 West Cumberland Avenue, Knoxville, TN 37996, USA
    Obes Res 13:670-7. 2005
    ..Accordingly, our objective was to investigate the role of 1,25-dihydroxyvitamin D3 in the modulation of adipocyte glucocorticoid metabolism...
  22. ncbi [Role of whey protein and whey components in weight management and energy metabolism]
    Michael B Zemel
    University of Tennessee, Tennessee, USA
    Wei Sheng Yan Jiu 38:114-7. 2009
    ..This article presents recent research progress on the role of whey protein and whey components in weight management and energy metabolism...
  23. ncbi Calcitriol and calcium regulate cytokine production and adipocyte-macrophage cross-talk
    Xiaocun Sun
    Department of Nutrition, University of Tennessee, Knoxville, TN 37996 1900, USA
    J Nutr Biochem 19:392-9. 2008
    ..The objective of this study was to investigate the effects of calcitriol on adipocyte and macrophage cytokine expression as well as release and on adipocyte-macrophage cross-talk in local modulation of inflammation...
  24. pmc Dairy attentuates oxidative and inflammatory stress in metabolic syndrome
    Renée A Stancliffe
    Department of Nutrition, The University of Tennessee, Knoxville, TN 37996 1920, USA
    Am J Clin Nutr 94:422-30. 2011
    ..We showed previously that dairy components suppress the adipocyte- and macrophage-mediated generation of reactive oxygen species and inflammatory cytokines and systemic oxidative and inflammatory biomarkers in obesity...
  25. ncbi Role of dietary calcium and dairy products in modulating adiposity
    Michael B Zemel
    Department of Nutrition, The University of Tennessee, Nutrition Institute, Knoxville, Tennessee 37996, USA
    Lipids 38:139-46. 2003
    ..These data indicate an important role for dairy products in both the prevention and treatment of obesity...
  26. pmc Synergistic effects of leucine and resveratrol on insulin sensitivity and fat metabolism in adipocytes and mice
    Antje Bruckbauer
    NuSirt Sciences Inc, 11020 Solway School Rd, Knoxville, TN, 37931, USA
    Nutr Metab (Lond) 9:77. 2012
    ..abstract:..
  27. ncbi Effects of mitochondrial uncoupling on adipocyte intracellular Ca(2+) and lipid metabolism
    Xiaocun Sun
    University of Tennessee, Knoxville, TN 37996, USA
    J Nutr Biochem 14:219-26. 2003
    ....
  28. pmc Effects of dairy intake on weight maintenance
    Michael B Zemel
    The University of Tennessee, Knoxville, TN, USA
    Nutr Metab (Lond) 5:28. 2008
    ..To compare the effects of low versus recommended levels of dairy intake on weight maintenance and body composition subsequent to weight loss...
  29. pmc Synergistic effects of metformin, resveratrol, and hydroxymethylbutyrate on insulin sensitivity
    Antje Bruckbauer
    NuSirt Sciences Inc, Knoxville, TN, USA
    Diabetes Metab Syndr Obes 6:93-102. 2013
    ....
  30. pmc Effects of dairy consumption on SIRT1 and mitochondrial biogenesis in adipocytes and muscle cells
    Antje Bruckbauer
    Department of Nutrition, University of Tennessee, Knoxville, TN, USA
    Nutr Metab (Lond) 8:91. 2011
    ..abstract:..
  31. ncbi Effects of dietary carbohydrate on the development of obesity in heterozygous Zucker rats
    Kristin L Morris
    Department of Nutrition, The University of Tennessee, Knoxville, TN 37996, USA
    J Nutr Biochem 14:32-9. 2003
    ..Therefore, diets that contain minimal carbohydrate may minimize net lipid storage and adiposity...
  32. pmc Leucine modulation of mitochondrial mass and oxygen consumption in skeletal muscle cells and adipocytes
    Xiaocun Sun
    University of Tennessee, Knoxville, Tennessee, 37996, USA
    Nutr Metab (Lond) 6:26. 2009
    ..abstract:..
  33. ncbi Effect of energy-reduced diets high in dairy products and fiber on weight loss in obese adults
    Warren G Thompson
    Mayo Clinic Graduate School of Medicine, Division of Preventive and Occupational Medicine, Rochester, MN 55905, USA
    Obes Res 13:1344-53. 2005
    ..The effects on weight loss and body fat of a high-dairy diet and a diet high in dairy and fiber and low in glycemic index were compared with a standard diet...
  34. ncbi Calcium and dairy modulation of obesity risk
    Michael B Zemel
    Obes Res 13:192-3. 2005
  35. ncbi Effect of low- and high-calcium dairy-based diets on macronutrient oxidation in humans
    Edward L Melanson
    Center for Human Nutrition, University of Colorado Health Sciences Center, Denver, 80262, USA
    Obes Res 13:2102-12. 2005
    ..Higher calcium and dairy intakes may be associated with lower body weights, but a mechanism in humans has yet to be elucidated. We compared the effects of a dairy-based high-calcium diet and a low-calcium diet on macronutrient oxidation...
  36. doi Calcium and dairy product modulation of lipid utilization and energy expenditure
    Dorothy Teegarden
    Interdepartmental Nutrition Program, Purdue University, West Lafayette, Indiana, USA
    Obesity (Silver Spring) 16:1566-72. 2008
    ..The purpose of this study was to investigate the impact of dietary calcium or dairy product intake on total energy expenditure (TEE), fat oxidation, and thermic effect of a meal (TEM) during a weight loss trial...
  37. ncbi Mechanisms of dairy modulation of adiposity
    Michael B Zemel
    Department of Nutrition, The University of Tennessee, Knoxville 37996, USA
    J Nutr 133:252S-256S. 2003
    ....
  38. ncbi Regulation of adiposity and obesity risk by dietary calcium: mechanisms and implications
    Michael B Zemel
    The University of Tennessee, Knoxville 37996, USA
    J Am Coll Nutr 21:146S-151S. 2002
    ....
  39. ncbi Functional properties of whey, whey components, and essential amino acids: mechanisms underlying health benefits for active people (review)
    Ewan Ha
    Functional Ingredients Research, Inc, Twin Falls, Idaho, USA
    J Nutr Biochem 14:251-8. 2003
    ..From a mechanistic standpoint, whey proteins, their composite amino acids, and/or associated compounds may be able to provide substrate and bioactive components to extend the overall benefits of physical activity...
  40. ncbi Dairy product components and weight regulation: symposium overview
    Dorothy Teegarden
    Purdue University, West Lafayette, IN, USA
    J Nutr 133:243S-244S. 2003