Benjamin H Chi

Summary

Affiliation: Centre for Infectious Disease Research in Zambia
Country: Zambia

Publications

  1. ncbi request reprint Single-dose tenofovir and emtricitabine for reduction of viral resistance to non-nucleoside reverse transcriptase inhibitor drugs in women given intrapartum nevirapine for perinatal HIV prevention: an open-label randomised trial
    Benjamin H Chi
    Centre for Infectious Disease Research in Zambia, Lusaka, Zambia
    Lancet 370:1698-705. 2007
  2. doi request reprint Extended nevirapine prophylaxis to prevent HIV transmission
    Jeffrey S A Stringer
    University of Alabama at Birmingham, Centre for Infectious Disease Research in Zambia CIDRZ, Lusaka, Zambia
    Lancet 372:267-9. 2008
  3. pmc Prevention of mother-to-child HIV transmission within the continuum of maternal, newborn, and child health services
    Benjamin H Chi
    Centre for Infectious Disease Research in Zambia CIDRZ, Lusaka, Zambia
    Curr Opin HIV AIDS 8:498-503. 2013
  4. pmc Antiretroviral drug regimens to prevent mother-to-child transmission of HIV: a review of scientific, program, and policy advances for sub-Saharan Africa
    Benjamin H Chi
    Centre for Infectious Disease Research in Zambia, Lusaka, Zambia
    Curr HIV/AIDS Rep 10:124-33. 2013
  5. pmc Nonvirologic algorithms for predicting HIV infection among HIV-exposed infants younger than 12 weeks of age
    Benjamin H Chi
    Centre for Infectious Disease Research in Zambia, Lusaka, Zambia
    Pediatr Infect Dis J 32:151-6. 2013
  6. doi request reprint Progress, challenges, and new opportunities for the prevention of mother-to-child transmission of HIV under the US President's Emergency Plan for AIDS Relief
    Benjamin H Chi
    Centre for Infectious Disease Research in Zambia, Lusaka, Zambia
    J Acquir Immune Defic Syndr 60:S78-87. 2012
  7. pmc Use of task-shifting to rapidly scale-up HIV treatment services: experiences from Lusaka, Zambia
    Mary B Morris
    Centre for Infectious Disease Research in Zambia Lusaka, Zambia
    BMC Health Serv Res 9:5. 2009
  8. pmc Universal definition of loss to follow-up in HIV treatment programs: a statistical analysis of 111 facilities in Africa, Asia, and Latin America
    Benjamin H Chi
    University of Alabama at Birmingham, Birmingham, Alabama, United States of America
    PLoS Med 8:e1001111. 2011
  9. ncbi request reprint Predictors of stillbirth in sub-saharan Africa
    Benjamin H Chi
    Centre for Infectious Disease Research in Zambia, Lusaka, Zambia
    Obstet Gynecol 110:989-97. 2007
  10. pmc Implementation of the Zambia electronic perinatal record system for comprehensive prenatal and delivery care
    Benjamin H Chi
    Centre for Infectious Disease Research in Zambia, Lusaka, Zambia
    Int J Gynaecol Obstet 113:131-6. 2011

Detail Information

Publications72

  1. ncbi request reprint Single-dose tenofovir and emtricitabine for reduction of viral resistance to non-nucleoside reverse transcriptase inhibitor drugs in women given intrapartum nevirapine for perinatal HIV prevention: an open-label randomised trial
    Benjamin H Chi
    Centre for Infectious Disease Research in Zambia, Lusaka, Zambia
    Lancet 370:1698-705. 2007
    ..We aimed to investigate whether this complication would be reduced with a single peripartum intervention of tenofovir and emtricitabine...
  2. doi request reprint Extended nevirapine prophylaxis to prevent HIV transmission
    Jeffrey S A Stringer
    University of Alabama at Birmingham, Centre for Infectious Disease Research in Zambia CIDRZ, Lusaka, Zambia
    Lancet 372:267-9. 2008
  3. pmc Prevention of mother-to-child HIV transmission within the continuum of maternal, newborn, and child health services
    Benjamin H Chi
    Centre for Infectious Disease Research in Zambia CIDRZ, Lusaka, Zambia
    Curr Opin HIV AIDS 8:498-503. 2013
    ..Although PMTCT have been traditionally aligned with maternal, newborn, and child health (MNCH) services, novel approaches are needed to address the increasing demands of evolving global PMTCT policies...
  4. pmc Antiretroviral drug regimens to prevent mother-to-child transmission of HIV: a review of scientific, program, and policy advances for sub-Saharan Africa
    Benjamin H Chi
    Centre for Infectious Disease Research in Zambia, Lusaka, Zambia
    Curr HIV/AIDS Rep 10:124-33. 2013
    ..In this review, we take stock of recent advances across each of these areas, highlighting the challenges--and opportunities--of improving health services for HIV-infected mothers and their children across the region...
  5. pmc Nonvirologic algorithms for predicting HIV infection among HIV-exposed infants younger than 12 weeks of age
    Benjamin H Chi
    Centre for Infectious Disease Research in Zambia, Lusaka, Zambia
    Pediatr Infect Dis J 32:151-6. 2013
    ..Early initiation of antiretroviral therapy has been shown to reduce mortality among perinatally HIV-infected infants, but availability of virologic testing remains limited in many settings...
  6. doi request reprint Progress, challenges, and new opportunities for the prevention of mother-to-child transmission of HIV under the US President's Emergency Plan for AIDS Relief
    Benjamin H Chi
    Centre for Infectious Disease Research in Zambia, Lusaka, Zambia
    J Acquir Immune Defic Syndr 60:S78-87. 2012
    ..PEPFAR must also carefully integrate PMTCT into the broader combination prevention agenda for HIV, so that real progress can be made toward an "AIDS-free generation" worldwide...
  7. pmc Use of task-shifting to rapidly scale-up HIV treatment services: experiences from Lusaka, Zambia
    Mary B Morris
    Centre for Infectious Disease Research in Zambia Lusaka, Zambia
    BMC Health Serv Res 9:5. 2009
    ..While this approach has been successful, long-term solutions to the human resource crisis are also urgently needed to expand the number of providers and to slow staff migration out of the region...
  8. pmc Universal definition of loss to follow-up in HIV treatment programs: a statistical analysis of 111 facilities in Africa, Asia, and Latin America
    Benjamin H Chi
    University of Alabama at Birmingham, Birmingham, Alabama, United States of America
    PLoS Med 8:e1001111. 2011
    ..We analyzed data from health facilities across Africa, Asia, and Latin America to empirically determine a standard LTFU definition...
  9. ncbi request reprint Predictors of stillbirth in sub-saharan Africa
    Benjamin H Chi
    Centre for Infectious Disease Research in Zambia, Lusaka, Zambia
    Obstet Gynecol 110:989-97. 2007
    ..To describe the incidence and predictors of stillbirth in a predominantly human immunodeficiency virus (HIV)-infected African cohort...
  10. pmc Implementation of the Zambia electronic perinatal record system for comprehensive prenatal and delivery care
    Benjamin H Chi
    Centre for Infectious Disease Research in Zambia, Lusaka, Zambia
    Int J Gynaecol Obstet 113:131-6. 2011
    ..To characterize prenatal and delivery care in an urban African setting...
  11. pmc An empirical approach to defining loss to follow-up among patients enrolled in antiretroviral treatment programs
    Benjamin H Chi
    Centre for Infectious Disease Research in Zambia, Box 34681, 1275 Lubuto Road, Lusaka, Zambia
    Am J Epidemiol 171:924-31. 2010
    ..This analysis suggests that > or =60 days since the last appointment is a reasonable definition of LTFU. Standardization to empirically derived definitions of LTFU will permit more reliable comparisons within and across programs...
  12. ncbi request reprint Perceptions toward HIV, HIV screening, and the use of antiretroviral medications: a survey of maternity-based health care providers in Zambia
    Benjamin H Chi
    Department of Obstetrics and Gynecology, Baylor College of Medicine, Houston, Texas, USA
    Int J STD AIDS 15:685-90. 2004
    ..Among those never prescribing ART, most cited a lack of availability (83%). Our results highlight the need for further provider education, critical appraisal of the current system for HIV testing, and widespread distribution of ART...
  13. pmc Early clinical and immune response to NNRTI-based antiretroviral therapy among women with prior exposure to single-dose nevirapine
    Benjamin H Chi
    Centre for Infectious Disease Research in Zambia, Zambia
    AIDS 21:957-64. 2007
    ....
  14. ncbi request reprint Field performance of a thin-layer chromatography assay for detection of nevirapine in umbilical cord blood
    Benjamin H Chi
    Centre for Infectious Disease Research in Zambia, Lusaka, Zambia
    HIV Clin Trials 7:263-9. 2006
    ..At present, the only validated method is high-performance liquid chromatography (HPLC), a technique poorly suited for most resource-constrained settings...
  15. ncbi request reprint Timing of maternal and neonatal dosing of nevirapine and the risk of mother-to-child transmission of HIV-1: HIVNET 024
    Benjamin H Chi
    University of Alabama at Birmingham, Department of Obstetrics and Gynecology, Birmingham, Alabama, USA
    AIDS 19:1857-64. 2005
    ..We analyzed data from a multicenter clinical trial to determine whether timing of maternal or infant NVP was associated with MTCT between delivery and 6 weeks of age (intrapartum/early postnatal transmission; I/EP)...
  16. ncbi request reprint HIVCorps: using volunteers to rapidly expand HIV health services across Zambia
    Benjamin H Chi
    Centre for Infectious Disease Research in Zambia, Lusaka, Zambia
    Am J Trop Med Hyg 74:918-21. 2006
    ..Formal volunteer programs like HIVCorps should be developed alongside initiatives focused on deploying more specialized, experienced healthcare workers aboard...
  17. pmc Measuring coverage in MNCH: population HIV-free survival among children under two years of age in four African countries
    Jeffrey S A Stringer
    Centre for Infectious Disease Research in Zambia, Lusaka, Zambia
    PLoS Med 10:e1001424. 2013
    ..We measured PMTCT service coverage, regimen use, and HIV-free survival among children ≤24 mo of age in Cameroon, Côte D'Ivoire, South Africa, and Zambia...
  18. pmc Intrapartum tenofovir and emtricitabine reduces low-concentration drug resistance selected by single-dose nevirapine for perinatal HIV prevention
    Benjamin H Chi
    Centre for Infectious Disease Research in Zambia, Lusaka, Zambia
    AIDS Res Hum Retroviruses 25:1099-106. 2009
    ..The ability of single-dose TDF/FTC to protect against peripartum NVP-induced NNRTI resistance extends to minority populations. This efficacy is achieved without significant selection of TDF- or FTC-resistant viruses...
  19. doi request reprint Addition of single-dose tenofovir and emtricitabine to intrapartum nevirapine to reduce perinatal HIV transmission
    Benjamin H Chi
    Centre for Infectious Disease Research in Zambia, Lusaka, Zambia
    J Acquir Immune Defic Syndr 48:220-3. 2008
    ..To determine the impact of adjuvant single-dose peripartum tenofovir/emtricitabine (TDF/FTC) on intrapartum/early postpartum HIV transmission...
  20. ncbi request reprint Rapid scale-up of antiretroviral therapy at primary care sites in Zambia: feasibility and early outcomes
    Jeffrey S A Stringer
    Schools of Medicine and Public Health, University of Alabama at Birmingham, Birmingham, USA
    JAMA 296:782-93. 2006
    ..The Zambian Ministry of Health has scaled-up human immunodeficiency virus/acquired immunodeficiency syndrome (HIV/AIDS) care and treatment services at primary care clinics in Lusaka, using predominately nonphysician clinicians...
  21. pmc Early clinical and programmatic outcomes with tenofovir-based antiretroviral therapy in Zambia
    Benjamin H Chi
    Centre for Infectious Disease Research in Zambia, Lusaka, Zambia
    J Acquir Immune Defic Syndr 54:63-70. 2010
    ..In July 2007, amid some controversy over cost, Zambia was the first African country to introduce tenofovir (TDF) as a component of first-line antiretroviral therapy (ART) on a wide scale...
  22. pmc Peripartum nevirapine exposure and subsequent clinical outcomes among HIV-infected women receiving antiretroviral therapy for at least 12 months
    Namwinga Chintu
    Centre for Infectious Disease Research in Zambia, Lusaka, Zambia
    Trop Med Int Health 15:842-7. 2010
    ..We examined the longer-term clinical outcomes in a programmatic setting...
  23. pmc Adherence to first-line antiretroviral therapy affects non-virologic outcomes among patients on treatment for more than 12 months in Lusaka, Zambia
    Benjamin H Chi
    Centre for Infectious Disease Research in Zambia, Lusaka, Zambia
    Int J Epidemiol 38:746-56. 2009
    ..In resource-constrained settings, however, there are few validated measures. We examined the correlation between clinical outcomes and the medication possession ratio (MPR), a pharmacy-based measure of adherence...
  24. pmc Predictors of CD4 eligibility for antiretroviral therapy initiation among HIV-infected pregnant women in Lusaka, Zambia
    Katherine C Liu
    Centre for Infectious Disease Research in Zambia, Lusaka, Zambia
    J Acquir Immune Defic Syndr 57:e101-5. 2011
    ..In resource-limited settings, CD4 testing is a barrier to antiretroviral therapy initiation in pregnancy...
  25. pmc Association between weight gain and clinical outcomes among malnourished adults initiating antiretroviral therapy in Lusaka, Zambia
    John R Koethe
    Centre for Infectious Disease Research in Zambia, Lusaka, Zambia
    J Acquir Immune Defic Syndr 53:507-13. 2010
    ..To describe the association between 6-month weight gain on antiretroviral therapy (ART) and subsequent clinical outcomes...
  26. pmc Six-month hemoglobin concentration and its association with subsequent mortality among adults on antiretroviral therapy in Lusaka, Zambia
    Mark J Giganti
    Centre for Infectious Disease Research in Zambia, Lusaka, Zambia
    J Acquir Immune Defic Syndr 61:120-3. 2012
    ..5; 95% confidence interval: 3.3 to 6.3). Future work should look to identify causes of anemia in settings such as ours and evaluate strategies for more timely diagnosis and treatment...
  27. doi request reprint Coverage of nevirapine-based services to prevent mother-to-child HIV transmission in 4 African countries
    Elizabeth M Stringer
    Centre for Infectious Disease Research in Zambia, Plot 1275 Lubutu Rd, PO Box 34681, Lusaka, Zambia
    JAMA 304:293-302. 2010
    ..Few studies have objectively evaluated the coverage of services to prevent transmission of human immunodeficiency virus (HIV) from mother to child...
  28. pmc HIV disease progression by hormonal contraceptive method: secondary analysis of a randomized trial
    Elizabeth M Stringer
    Centre for Infectious Disease Research, Lusaka, Zambia
    AIDS 23:1377-82. 2009
    ..We hypothesized that women using depomedroxyprogesterone acetate (DMPA) contraception would have faster HIV disease progression than women using oral contraceptive pills (OCPs) and nonhormonal methods...
  29. ncbi request reprint Acute and chronic chorioamnionitis and the risk of perinatal human immunodeficiency virus-1 transmission
    Benjamin H Chi
    School of Medicine, University of Alabama, Birmingham, AL 35294 0024, USA
    Am J Obstet Gynecol 194:174-81. 2006
    ..This study was undertaken to examine the prevalence of acute and chronic chorioamnionitis among women infected with human immunodeficiency virus-1 (HIV-1) and to determine the relative contribution of each to perinatal HIV-1 transmission...
  30. doi request reprint Determinants of stillbirth in Zambia
    Elizabeth M Stringer
    University of Alabama at Birmingham School of Medicine, Birmingham, Alabama, USA
    Obstet Gynecol 117:1151-9. 2011
    ..The objective of this study was to estimate the rates and determinants of stillbirth in an urban African obstetric population...
  31. ncbi request reprint Clinical outcomes and CD4 cell response in children receiving antiretroviral therapy at primary health care facilities in Zambia
    Carolyn Bolton-Moore
    Centre for Infectious Disease Research in Zambia, Lusaka
    JAMA 298:1888-99. 2007
    ....
  32. pmc A pilot study of food supplementation to improve adherence to antiretroviral therapy among food-insecure adults in Lusaka, Zambia
    Ronald A Cantrell
    Centre for Infectious Disease Research in Zambia, Plot 1275 Lubutu Road, Lusaka, Zambia
    J Acquir Immune Defic Syndr 49:190-5. 2008
    ..The provision of food supplementation to food-insecure patients initiating antiretroviral therapy (ART) may improve adherence to medications...
  33. pmc Influence of body mass index on pregnancy outcomes among HIV-infected and HIV-uninfected Zambian women
    Yolan Banda
    School of Medicine, University of Zambia, Lusaka, Zambia
    Trop Med Int Health 12:856-61. 2007
    ..To determine the influence of body mass index (BMI) on pregnancy outcomes of HIV-infected and HIV-uninfected Zambian women and to assess the possible role of BMI on mother-to-child transmission rate of HIV...
  34. pmc CD4+ response and subsequent risk of death among patients on antiretroviral therapy in Lusaka, Zambia
    Benjamin H Chi
    Centre for Infectious Disease Research in Zambia, Lusaka, Zambia
    J Acquir Immune Defic Syndr 52:125-31. 2009
    ..However, few have studied CD4+ response and its relationship to subsequent clinical outcomes in a programmatic setting...
  35. pmc Effectiveness of generic and proprietary first-line anti-retroviral regimens in a primary health care setting in Lusaka, Zambia: a cohort study
    Jeffrey S A Stringer
    Centre for Infectious Disease Research in Zambia, Lusaka, Zambia
    Int J Epidemiol 41:448-59. 2012
    ..Although generic anti-retroviral drugs are in common use throughout the developing world, studies comparing their clinical effectiveness with that of proprietary formulations are lacking...
  36. pmc Declining HIV prevalence among young pregnant women in Lusaka, Zambia
    Elizabeth M Stringer
    Department of Obstetrics and Gynecology, University of Alabama, Birmingham, AL, United States of America
    Bull World Health Organ 86:697-702. 2008
    ..Recent reports suggest a possible decline in HIV sero-incidence in Zambia and some neighbouring countries. This study aimed to examine trends in HIV seroprevalence among pregnant and parturient women between 2002 and 2006...
  37. pmc Causes of morbidity among HIV-infected children on antiretroviral therapy in primary care facilities in Lusaka, Zambia
    Mwangelwa Mubiana-Mbewe
    Centre for Infectious Disease Research in Zambia, Lusaka, Zambia
    Trop Med Int Health 14:1190-8. 2009
    ..To describe the pattern of incident illness in children after initiation of antiretroviral therapy (ART) in a large public health sector programme in Lusaka, Zambia...
  38. pmc Early immunologic response and subsequent survival among malnourished adults receiving antiretroviral therapy in Urban Zambia
    John R Koethe
    Centre for Infectious Disease Research in Zambia, Lusaka, Zambia
    AIDS 24:2117-21. 2010
    ..To evaluate the relationship between early CD4(+) lymphocyte recovery on antiretroviral therapy (ART) and subsequent survival among low body mass index (BMI) HIV-1-infected adults...
  39. doi request reprint Implementation and Operational Research: Reconstructing the PMTCT Cascade Using Cross-sectional Household Survey Data: The PEARL Study
    Benjamin H Chi
    University of North Carolina at Chapel Hill, Chapel Hill, NC Centre for Infectious Disease Research in Zambia, Lusaka, Zambia Cameroon Baptist Health Convention Health Board, Bamenda, Cameroon University of Cape Town, Cape Town, South Africa INSERM, centre Inserm U897, Bordeaux, France University of Bordeaux, ISPED, centre Inserm U897, Bordeaux, France Programme PAC CI, Abidjan, Cote d Ivoire Zambian Ministry of Health, Lusaka, Zambia and World Health Organization, Geneva, Switzerland
    J Acquir Immune Defic Syndr 70:e5-9. 2015
    ..The concept of a "PMTCT cascade" has been used widely to identify bottlenecks in program implementation; however, most efforts to reconstruct the cascade have relied on facility-based approaches that may limit external validity...
  40. ncbi request reprint Cost and enrollment implications of targeting different source population for an HIV treatment program
    Benjamin H Chi
    Centre for Infectious Disease Research in Zambia, Lusaka, Zambia
    J Acquir Immune Defic Syndr 40:350-5. 2005
    ..Rapid scale-up of antiretroviral therapy (ART) is a worldwide priority, and ambitious targets for numbers on ART have been set. Antenatal clinics (ANCs) and tuberculosis (TB) clinics have been targeted as entry points into HIV care...
  41. pmc Modern contraceptive and dual method use among HIV-infected women in Lusaka, Zambia
    Carla J Chibwesha
    University of Alabama School of Medicine, Birmingham, AL 35294, USA
    Infect Dis Obstet Gynecol 2011:261453. 2011
    ..6% of these women successfully accessed services within 90 days. Unmet contraceptive need remains high among HIV-infected women. Additional efforts are needed to promote reproductive health, particularly dual method use...
  42. pmc Comparative outcomes of tenofovir-based and zidovudine-based antiretroviral therapy regimens in Lusaka, Zambia
    Benjamin H Chi
    Centre for Infectious Disease Research in Zambia, Lusaka, Zambia
    J Acquir Immune Defic Syndr 58:475-81. 2011
    ..Although tenofovir (TDF) is a common component of antiretroviral therapy (ART), recent evidence suggests inferior outcomes when it is combined with nevirapine (NVP)...
  43. pmc A cluster randomized trial of routine HIV-1 viral load monitoring in Zambia: study design, implementation, and baseline cohort characteristics
    John R Koethe
    Centre for Infectious Disease Research in Zambia, Lusaka, Zambia
    PLoS ONE 5:e9680. 2010
    ....
  44. pmc A randomized trial of the intrauterine contraceptive device vs hormonal contraception in women who are infected with the human immunodeficiency virus
    Elizabeth M Stringer
    Centre for Infectious Disease Research in Zambia, Lusaka, Zambia
    Am J Obstet Gynecol 197:144.e1-8. 2007
    ..The purpose of this study was to determine whether the intrauterine contraceptive device (IUD) is effective and safe among women who are infected with the human immunodeficiency virus (HIV)...
  45. pmc Methods and baseline results of a repeated cross-sectional survey to assess the public health impact of antiretroviral therapy in Lusaka, Zambia
    Mark J Giganti
    Centre for Infectious Disease Research in Zambia, Box 34681, Plot 1275, Lubuto Road, Lusaka, Zambia
    Am J Trop Med Hyg 82:971-7. 2010
    ..These findings will serve as a reliable reference in the future analysis of the population-level impact of this HIV treatment and care program in Zambia...
  46. pmc Monitoring effectiveness of programmes to prevent mother-to-child HIV transmission in lower-income countries
    Elizabeth M Stringer
    Centre for Infectious Disease Research in Zambia, Lusaka, Zambia
    Bull World Health Organ 86:57-62. 2008
    ..Finally, we propose a novel community survey-based approach that could be implemented widely throughout the developing world with minor modifications to ongoing Demographic and Health Surveys...
  47. ncbi request reprint Use of traditional medicine among pregnant women in Lusaka, Zambia
    Yolan Banda
    University of Zambia School of Medicine, Lusaka, Zambia
    J Altern Complement Med 13:123-7. 2007
    ..We studied the prevalence of and predictors for traditional medicine use among pregnant women seeking care in the Lusaka, Zambia public health system...
  48. pmc Predictors and pregnancy outcomes associated with a newborn birth weight of 4000 g or more in Lusaka, Zambia
    Katherine C Liu
    Centre for Infectious Disease Research in Zambia, Lusaka, Zambia
    Int J Gynaecol Obstet 122:150-5. 2013
    ..To identify predictors and outcomes associated with a birth weight of 4000g or more in Lusaka, Zambia...
  49. pmc Causes of stillbirth, neonatal death and early childhood death in rural Zambia by verbal autopsy assessments
    Eleanor Turnbull
    Centre for Infectious Disease Research in Zambia, Lusaka, Zambia
    Trop Med Int Health 16:894-901. 2011
    ..To describe specific causes of the high rates of stillbirth, neonatal death and early child childhood death in Zambia...
  50. pmc Serum phosphate predicts early mortality in adults starting antiretroviral therapy in Lusaka, Zambia: a prospective cohort study
    Douglas C Heimburger
    Centre for Infectious Disease Research in Zambia, Lusaka, Zambia
    PLoS ONE 5:e10687. 2010
    ..We assessed the association of serum phosphate with early mortality among HIV-infected adults with severe malnutrition and/or advanced immunosuppression...
  51. doi request reprint The burden of cervical pre-cancer and cancer in HIV positive women in Zambia: a modeling study
    Allen C Bateman
    Centre for Infectious Disease Research in Zambia, Lusaka, Zambia
    BMC Cancer 15:541. 2015
    ..The objective of this study was to determine the burden of cervical disease among HIV positive women in Zambia by estimating the number with CIN3 and ICC...
  52. pmc Optimal time on HAART for prevention of mother-to-child transmission of HIV
    Carla J Chibwesha
    University of Alabama at Birmingham School of Medicine, Birmingham, AL, USA
    J Acquir Immune Defic Syndr 58:224-8. 2011
    ..To determine the impact of time between initiating highly active antiretroviral therapy (HAART) and delivery-duration of antenatal HAART-on perinatal HIV infection...
  53. doi request reprint Temporal Trends and Predictors of Modern Contraceptive Use in Lusaka, Zambia, 2004-2011
    Nancy L Hancock
    Department of Obstetrics and Gynecology, University of North Carolina School of Medicine, 3009 Old Clinic Building, Campus Box 7570, Chapel Hill, NC 27599 7570, USA Centre for Infectious Disease Research in Zambia, 5032 Great North Road, P O Box 34681, 10101 Lusaka, Zambia
    Biomed Res Int 2015:521928. 2015
    ..To achieve reproductive health equity and reduce unmet contraceptive need, future efforts to increase LARC use should focus on young women and those with less education. ..
  54. doi request reprint Implementation and Operational Research: Distance From Household to Clinic and Its Association With the Uptake of Prevention of Mother-to-Child HIV Transmission Regimens in Rural Zambia
    Veronica Escamilla
    Department of Obstetrics and Gynecology, University of Chicago, Chicago, IL Centre for Infectious Disease Research in Zambia, Lusaka, Zambia Department of Obstetrics and Gynecology, University of North Carolina, Chapel Hill, NC Institute for Global Health, Vanderbilt University, Nashville, TN Society for Family Health, Lusaka, Zambia Zambian Ministry of Community Development and Mother Child Health, Lusaka, Zambia Department of Public Health, University of Zambia School of Medicine, Lusaka, Zambia Division of Infectious Diseases, Department of Medicine, School of Medicine, University of North Carolina, Chapel Hill, NC Department of Epidemiology, Gillings School of Public Health, University of North Carolina, Chapel Hill, NC and Currently at Departments of Medicine and Pediatrics, Massachusetts General Hospital Boston, MA
    J Acquir Immune Defic Syndr 70:e94-e101. 2015
    ..In rural settings, HIV-infected pregnant women often live significant distances from facilities that provide prevention of mother-to-child transmission (PMTCT) services...
  55. pmc Age at antiretroviral therapy initiation predicts immune recovery, death, and loss to follow-up among HIV-infected adults in urban Zambia
    Michael J Vinikoor
    1 Centre for Infectious Disease Research in Zambia, Lusaka, Zambia
    AIDS Res Hum Retroviruses 30:949-55. 2014
    ..HIV treatment guidelines should consider age-specific recommendations...
  56. pmc A controlled trial of three methods for neonatal circumcision in Lusaka, Zambia
    Kasonde Bowa
    Department of Surgery, Copperbelt University School of Medicine, Ndola, Zambia
    J Acquir Immune Defic Syndr 62:e1-6. 2013
    ..Neonatal male circumcision (NMC) is not routinely practiced in Zambia, but it is a promising long-term HIV prevention strategy. We studied the feasibility and safety of three different NMC methods...
  57. pmc Simple adherence assessments to predict virologic failure among HIV-infected adults with discordant immunologic and clinical responses to antiretroviral therapy
    Jason D Goldman
    Centre for Infectious Disease Research in Zambia, Lusaka, Zambia
    AIDS Res Hum Retroviruses 24:1031-5. 2008
    ..Among patients with suspected treatment failure, a lower MPR was associated with higher rates of detectable viremia. However, the suboptimal sensitivity and specificity of MPR limit its utility as a sole predictor of virologic failure...
  58. pmc Macronutrient supplementation for malnourished HIV-infected adults: a review of the evidence in resource-adequate and resource-constrained settings
    John R Koethe
    Centre for Infectious Disease Research in Zambia, Lusaka, Zambia
    Clin Infect Dis 49:787-98. 2009
    ....
  59. pmc Short communication: Late refills during the first year of antiretroviral therapy predict mortality and program failure among HIV-infected adults in urban Zambia
    Michael J Vinikoor
    1 Centre for Infectious Disease Research in Zambia, Lusaka, Zambia
    AIDS Res Hum Retroviruses 30:74-7. 2014
    ..Monitoring late refills during the initial period of ART may help resource- and time-constrained clinics identify patients at risk for program failure...
  60. pmc A mobile phone-based, community health worker program for referral, follow-up, and service outreach in rural Zambia: outcomes and overview
    Linnaea Schuttner
    1 Centre for Infectious Disease Research in Zambia, Lusaka, Zambia
    Telemed J E Health 20:721-8. 2014
    ..As part of a primary care improvement project, a pilot CHW program was developed using a mobile phone-based application for outreach, referral, and follow-up between the clinic and community in rural Zambia...
  61. pmc HIV, Hepatitis B, and Hepatitis C in Zambia
    Kenneth C Kapembwa
    Department of Internal Medicine, School of Medicine, University of Zambia, Lusaka, Zambia
    J Glob Infect Dis 3:269-74. 2011
    ..Epidemiologic data of HIV and viral hepatitis coinfection are needed in sub-Saharan Africa to guide health policy for hepatitis screening and optimized antiretroviral therapy (ART)...
  62. doi request reprint Prevalence of hypertension and its treatment among adults presenting to primary health clinics in rural Zambia: analysis of an observational database
    Lily D Yan
    Primary Care and Health Systems Department, Center for Infectious Disease Research Zambia, Lusaka, Zambia
    BMC Public Health 15:933. 2015
    ....
  63. doi request reprint Hepatitis B viral load in dried blood spots: A validation study in Zambia
    Michael J Vinikoor
    Department of Medicine, University of Alabama at Birmingham, USA Centre for Infectious Disease Research in Zambia, Lusaka, Zambia School of Medicine, University of Zambia, Lusaka, Zambia Electronic address
    J Clin Virol 72:20-4. 2015
    ..Access to hepatitis B viral load (VL) testing is poor in sub-Saharan Africa (SSA) due to economic and logistical reasons...
  64. pmc Characterization of HIV drug resistance mutations among patients failing first-line antiretroviral therapy from a tertiary referral center in Lusaka, Zambia
    Lillian Seu
    School of Medicine, University of Alabama at Birmingham, Alabama Centre for Infectious Disease Research Zambia, Lusaka, Zambia
    J Med Virol 87:1149-57. 2015
    ..Closer monitoring of DRM mutations at first-line failure can inform clinicians about future options for salvage therapy...
  65. pmc Population-level scale-up of cervical cancer prevention services in a low-resource setting: development, implementation, and evaluation of the cervical cancer prevention program in Zambia
    Groesbeck P Parham
    Center for Infectious Disease Research in Zambia, Lusaka, Zambia University of Zambia, Lusaka, Zambia University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States of America International Agency for Research on Cancer, Lyon, France
    PLoS ONE 10:e0122169. 2015
    ..Very few efforts have been undertaken to scale-up low-cost approaches to cervical cancer prevention in low-resource countries...
  66. pmc Chronic hepatitis B virus coinfection is associated with renal impairment among Zambian HIV-infected adults
    Aggrey Mweemba
    Department of Medicine, University of Zambia University Teaching Hospital, Lusaka, Zambia
    Clin Infect Dis 59:1757-60. 2014
    ..73 m(2) (adjusted odds ratio, 1.96 [95% confidence interval, 1.34-2.86]), adjusted for age, sex, CD4(+) count, and World Health Organization disease stage. ..
  67. pmc Burnout and use of HIV services among health care workers in Lusaka District, Zambia: a cross-sectional study
    Gina R Kruse
    Centre for Infectious Disease Research in Zambia CIDRZ, Lusaka, Zambia
    Hum Resour Health 7:55. 2009
    ..Programmes to improve access, acceptability and confidentiality of health care services for clinical providers and to reduce workplace stress could substantially affect workforce stability...
  68. pmc Baseline renal insufficiency and risk of death among HIV-infected adults on antiretroviral therapy in Lusaka, Zambia
    Lloyd B Mulenga
    Centre for Infectious Disease Research, Zambia
    AIDS 22:1821-7. 2008
    ..To examine the association between baseline renal insufficiency and mortality among adults initiating antiretroviral therapy (ART) in an urban African setting...
  69. pmc Abandonment of antiretroviral therapy: a potential barrier to scale-up in sub-Saharan Africa
    Stewart E Reid
    S Afr Med J 98:448, 450. 2008
  70. ncbi request reprint Expanded services for the prevention of mother-to-child HIV transmission: field acceptability of a pilot program in Lusaka, Zambia
    Benjamin H Chi
    J Acquir Immune Defic Syndr 45:125-7. 2007
  71. ncbi request reprint Individual-level predictors for HIV testing among antenatal attendees in Lusaka, Zambia
    Sara Thierman
    University of California School of Medicine, San Francisco, California, USA
    Am J Med Sci 332:13-7. 2006
    ..Because individual-level characteristics were only weakly predictive of HIV testing, future work should concentrate on community-level factors...
  72. ncbi request reprint Employment of off-duty staff: a strategy to meet the human resource needs for a large PMTCT program in Zambia
    Benjamin H Chi
    J Acquir Immune Defic Syndr 40:381-2. 2005