Zahra Zakeri

Summary

Publications

  1. ncbi request reprint Caspase-independent cell deaths
    Richard A Lockshin
    Department of Biological Sciences, St John s University, 8000 Utopia Parkway, Jamaica, NY 11439, USA
    Curr Opin Cell Biol 14:727-33. 2002
  2. pmc Sex-dependent regulation of cytochrome P450 family members Cyp1a1, Cyp2e1, and Cyp7b1 by methylation of DNA
    Carlos G Penaloza
    1Queens College, City University of New York, 65 30 Kissena Blvd, NSB E143, Flushing, NY 11367, USA
    FASEB J 28:966-77. 2014
  3. doi request reprint Cell death: history and future
    Zahra Zakeri
    Department of Biology, Queens College and the Graduate Center of the City University of New York, 65 30 Kissena Blvd, Flushing, New York 11361, USA
    Adv Exp Med Biol 615:1-11. 2008
  4. pmc Sex of the cell dictates its response: differential gene expression and sensitivity to cell death inducing stress in male and female cells
    Carlos Penaloza
    Queens College and Graduate Center of the City University of New York, 65 30 Kissena Blvd, Flushing, NY 11367, USA
    FASEB J 23:1869-79. 2009
  5. pmc mTOR/p70S6K signaling distinguishes routine, maintenance-level autophagy from autophagic cell death during influenza A infection
    Emmanuel Datan
    Department of Biology, Queens College and Graduate Center of the City University of New York, 65 30 Kissena Boulevard, Flushing, NY 11367, USA
    Virology 452:175-90. 2014
  6. ncbi request reprint Cell death in development: shaping the embryo
    Carlos Penaloza
    Department of Biology, Queens College and Graduate Center of CUNY, Flushing, NY 11367, USA
    Histochem Cell Biol 126:149-58. 2006
  7. doi request reprint Detection of autophagy in cell death
    Zahra Zakeri
    Department of Biology, Queens College and Graduate Center of the City University of New York, Flushing, New York, USA
    Methods Enzymol 442:289-306. 2008
  8. pmc Activation of cyclin-dependent kinase 5 is a consequence of cell death
    Yixia Ye
    Department of Biology, Queens College and Graduate Center of the City University of New York, Flushing, NY 11367, USA
    J Biomed Biotechnol 2009:805709. 2009
  9. ncbi request reprint A generalized caspase inhibitor disrupts early mammalian development
    Zahra Zakeri
    Department of Biology, Queens College and Graduate Center of the City University of New York, New York, USA
    Int J Dev Biol 49:43-7. 2005
  10. ncbi request reprint Caspase-independent cell death?
    Richard A Lockshin
    Department of Biology, Queens College and Graduate Center of the City University of New York, 65 30 Kissena Blvd, Flushing, NY 11367, USA
    Oncogene 23:2766-73. 2004

Research Grants

  1. Meeting: Mechanisms of Cell Death
    Zahra Zakeri; Fiscal Year: 2004
  2. Scientific Meeting: Mechanisms of Cell Death
    Zahra Zakeri; Fiscal Year: 2006
  3. MARC UNDERGRADUATE STUDENT TRAINING IN ACADEMIC RESEARCH
    Zahra Zakeri; Fiscal Year: 2007

Collaborators

Detail Information

Publications14

  1. ncbi request reprint Caspase-independent cell deaths
    Richard A Lockshin
    Department of Biological Sciences, St John s University, 8000 Utopia Parkway, Jamaica, NY 11439, USA
    Curr Opin Cell Biol 14:727-33. 2002
    ..We do not yet understand the extent to which the pathways are linked, what mechanisms trigger the caspase-independent deaths, and how the choices are made...
  2. pmc Sex-dependent regulation of cytochrome P450 family members Cyp1a1, Cyp2e1, and Cyp7b1 by methylation of DNA
    Carlos G Penaloza
    1Queens College, City University of New York, 65 30 Kissena Blvd, NSB E143, Flushing, NY 11367, USA
    FASEB J 28:966-77. 2014
    ..Sex-differential methylation may have medical effects...
  3. doi request reprint Cell death: history and future
    Zahra Zakeri
    Department of Biology, Queens College and the Graduate Center of the City University of New York, 65 30 Kissena Blvd, Flushing, New York 11361, USA
    Adv Exp Med Biol 615:1-11. 2008
    ..A cell that has passed the commitment stage but is blocked from undergoing apoptosis will die by another route. We still must learn much more about how a cell commits to death and what makes it choose a path to die...
  4. pmc Sex of the cell dictates its response: differential gene expression and sensitivity to cell death inducing stress in male and female cells
    Carlos Penaloza
    Queens College and Graduate Center of the City University of New York, 65 30 Kissena Blvd, Flushing, NY 11367, USA
    FASEB J 23:1869-79. 2009
    ..We conclude that cells differ innately according to sex irrespective of their history of exposure to sex hormones. These differences may have consequences in the course of sexually dimorphic diseases and their therapy...
  5. pmc mTOR/p70S6K signaling distinguishes routine, maintenance-level autophagy from autophagic cell death during influenza A infection
    Emmanuel Datan
    Department of Biology, Queens College and Graduate Center of the City University of New York, 65 30 Kissena Boulevard, Flushing, NY 11367, USA
    Virology 452:175-90. 2014
    ..Inhibitors of expanded autophagy limit virus reproduction. Thus expanded, lethal autophagy is activated by a signaling mechanism different from autophagy that helps cells survive toxic or stressful episodes. ..
  6. ncbi request reprint Cell death in development: shaping the embryo
    Carlos Penaloza
    Department of Biology, Queens College and Graduate Center of CUNY, Flushing, NY 11367, USA
    Histochem Cell Biol 126:149-58. 2006
    ....
  7. doi request reprint Detection of autophagy in cell death
    Zahra Zakeri
    Department of Biology, Queens College and Graduate Center of the City University of New York, Flushing, New York, USA
    Methods Enzymol 442:289-306. 2008
    ....
  8. pmc Activation of cyclin-dependent kinase 5 is a consequence of cell death
    Yixia Ye
    Department of Biology, Queens College and Graduate Center of the City University of New York, Flushing, NY 11367, USA
    J Biomed Biotechnol 2009:805709. 2009
    ..Thus its activation suggests processes during cell death that will be interesting or important to understand, but activation of Cdk5 is not necessary for cells to die...
  9. ncbi request reprint A generalized caspase inhibitor disrupts early mammalian development
    Zahra Zakeri
    Department of Biology, Queens College and Graduate Center of the City University of New York, New York, USA
    Int J Dev Biol 49:43-7. 2005
    ..Our results indicate that the early deaths are not caspase-dependent and that there is a role for caspase activity in early embryos, which is not related to cell death...
  10. ncbi request reprint Caspase-independent cell death?
    Richard A Lockshin
    Department of Biology, Queens College and Graduate Center of the City University of New York, 65 30 Kissena Blvd, Flushing, NY 11367, USA
    Oncogene 23:2766-73. 2004
    ..Experimental and therapeutic procedures must account for this possibility...
  11. pmc Flavivirus NS4A-induced autophagy protects cells against death and enhances virus replication
    Jeffrey E McLean
    Department of Biology, Queens College and Graduate Center of City University of New York, Flushing, New York 11367, USA
    J Biol Chem 286:22147-59. 2011
    ..As autophagy is vital to flavivirus replication in these cells, NS4A is therefore also identified as a critical determinant of flavivirus replication...
  12. doi request reprint Methods in enzymolology book on cell death
    Roya Khosravi-Far
    Methods Enzymol 446:xxi-xxii. 2008
  13. ncbi request reprint Cell death in health and disease
    Richard A Lockshin
    Department of Biological Sciences, St John s University, Queens, NY 11439, USA
    J Cell Mol Med 11:1214-24. 2007
    ..In the future, the challenge will be more to understand the challenge to the cell from a more global standpoint, including many more aspects of metabolism, and work toward alleviating or provoking the challenge in a targeted fashion...
  14. ncbi request reprint Apoptosis, autophagy, and more
    Richard A Lockshin
    Department of Biological Sciences, St John s University, 8000 Utopia Parkway, Jamaica, NY 11439, USA
    Int J Biochem Cell Biol 36:2405-19. 2004
    ..Since switching among the alternative pathways to death is relatively common, interpretations based on knockouts or inhibitors, and therapies directed at controlling apoptosis must include these considerations...

Research Grants5

  1. Meeting: Mechanisms of Cell Death
    Zahra Zakeri; Fiscal Year: 2004
    ..We expect that this meeting will lead to further publications. ..
  2. Scientific Meeting: Mechanisms of Cell Death
    Zahra Zakeri; Fiscal Year: 2006
    ..We expect that this meeting will lead to further publications. We are currently negotiating publication arrangements. NIH funds will be used to support speakers and facilities. Future meetings in France and China are planned. ..
  3. MARC UNDERGRADUATE STUDENT TRAINING IN ACADEMIC RESEARCH
    Zahra Zakeri; Fiscal Year: 2007
    ..The data will be made available to evaluator and an external advisory committee. ..