R Zahn

..We sought to determine the efficacy of enoxaparin in unselected patients with STEMI treated with primary percutaneous coronary intervention in clinical practice...

..To determine the influence of the side intervened upon on outcomes during carotid artery stenting (CAS)...

..However, at least in regions with a high density of invasive centers, such networks should take the investigators' experience and the annual interventional volumes of the participating hospitals into account...

..Although differences were found in its frequency among the participating hospitals, the presence of a porcelain aorta was not associated with in-hospital death or stroke...

..To obtain long-term follow-up data of the sirolimus-eluting coronary stent (SES) and to determine factors associated with clinical events and target vessel revascularization (TVR)...

..Recurrences of Takotsubo Cardiomyopathy, especially in variant regions of the left ventricle are rareWe describe a midventricular form of Takotsubo Cardiomyopathy as a recurrence 1 year after typical apical ballooning...

..We sought to compare the efficacy of a filter embolic protection device (F-EPD) and a distal occlusive embolic protection device (DO-EPD) in patients undergoing carotid artery stenting (CAS)...

..The management of bypass grafts and multiple lesions in 1 session and the presence of multivessel disease were predictors of MACCEs or TVR...

..However, because of safety concerns and frequent "off-label" use data from "real life," registries are necessary to monitor indications and outcome of DES in daily clinical practice...

..Concerning this pathophysiology, a further TAVI was performed using a second 29-mm CoreValve Revalving system, as a "valve-in-valve" implantation...

..However, its feasibility and safety in clinical practice at a broad spectrum of hospitals needs to be determined...

..To compare characteristics and outcome of patients with re-stenoses after prior carotid artery stenting (CAS) treated with repeat carotid interventions (Re-CI) with CAS for de novo lesions...

..However, CAS itself can cause cerebral ischaemic events. Embolic protection devices (PD) promise to reduce the incidence of these events...

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..The formerly observed volume-outcome relation for percutaneous coronary interventions (PCIs) has recently been questioned...

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..We tried to determine the influence of age on complication rates of carotid artery stenting (CAS)...

..Due to limited budgets in Germany, no special reimbursement has been given for their use and therefore they were mainly used in selected patients...

..Glycoprotein II b/IIIa antagonists (GPII b/IIIa-A) lower the periprocedural rate of ischemic events during high risk percutaneous coronary interventions. Their clinical impact on carotid artery stenting (CAS) remains to be determined...

..Treatment of restenosis following intracoronary brachytherapy (ICB) is still a challenging problem. Implantation of sirolimus-eluting stents (SES) in this setting may be an option to be evaluated...

..The characterization of AMI patients according to this definition is still incomplete...

..However, the value of CAS is still a matter of debate. Therefore, we performed a metaanalysis of the randomized controlled clinical trials (RCT) on this issue...

..To determine the predictors of time between presentation and primary angioplasty and the influence of this delay time on in-hospital mortality in clinical practice...

..Therefore, actual clinical practice may be very different to RCT...

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..In patients with acute myocardial infarction treated with thrombolysis, longer times to treatment are associated with increasingly worse clinical outcome. This relation may be different for treatment with primary angioplasty...

..We sought to determine the effectiveness of primary angioplasty compared with thrombolysis in clinical practice...

..There are no data addressing whether this time limit is also justified for treatment with primary angioplasty...

..In Germany this goal is achievable almost everywhere. Therefore it is currently the most important task to establish local networks to reach this goal...

..The proportion of transferred patients increased from 1.1% in 1994 to 5.5% in 1998. Contraindications for thrombolysis were the strongest predictor to transfer patients to primary angioplasty...

..Thus, the MIR data showed no protective effects of preinfarction angina in patients with AMI treated with primary angioplasty...

..We investigated changes in the clinical outcome of primary angioplasty and thrombolysis for the treatment of acute myocardial infarction (AMI) from 1994 to 1998...

..This association was significant only for men. It may indicate a contribution of the APC resistance to the development of CAD, which has to be proven by the follow-up...

..AMI patients treated with thrombolysis were more likely to be treated with either percutaneous coronary intervention or coronary bypass surgery after discharge...

..We investigated whether treatment with the macrolide antibiotic roxithromycin would reduce mortality or morbidity in patients with an acute myocardial infarction...

..Under the circumstances of frozen medical budgets in Germany, there may also be a shift toward implantation of a drug-eluting stent (DES) for indications not yet evaluated by RCTs...

..We report the first results of the prospective multi-centre German Transcatheter Aortic Valve Interventions-Registry...

..We describe the baseline characteristics and clinical course of patients who had an acute myocardial infarction (AMI) during their hospital stay...

..It remains unknown whether the ACT-prolonging effect of abciximab is clinically equivalent to a comparable degree of anti-coagulation by heparin...

..Its effectiveness in daily clinical practice in unselected patients remains to be determined...

..However, a potential problem of TAVI is the development of severe aortic insufficiency after valve implantation due to a too-low implantation of the valve...

..82, p < 0.0001) in the different subgroups, which showed an increasing absolute benefit of primary angioplasty compared to thrombolysis with increasing mortality risk...

..Thrombolysis is associated with a higher and beta blockers with a lower incidence of RE-AMI. Once a RE-AMI occurs, it is a strong predictor of in-hospital mortality and morbidity...

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..Following transcatheter aortic valve implantation (TAVI), AR is common, but little is known about its determinants and its effect on clinical outcome...

..pneumoniae and treatment with roxithromycin did not influence these events, independently of the serostatus against C. pneumoniae. However, the power of this subgroup analysis was low to detect small but significant differences...

..However, not all patients receive aspirin for AMI. The aim of this study was to provide information on characteristics and clinical course of patients not treated with aspirin for AMI...

..The ALKK registry contains about 20% of the invasive and interventional cardiological procedures performed in Germany...

..In addition to lesion characteristics, particularly stenting is associated with an increased rate of elevated troponin...

..Although it has become standard practice to perform electrophysiologic studies in patients with unexplained syncope, limited information exists on prognosis after therapy guided by electrophysiologic studies...

..To assess the safety and effectiveness of abciximab in patients with ST elevation myocardial infarction (STEMI) treated with primary percutaneous coronary intervention (PCI) in clinical practice...

..Hospital mortality in those patients is very high. Primary PCI improves the prognosis and is therefore the preferred reperfusion strategy in these patients...

..However, it is invasive with possible procedure-related complications. Therefore, it would be helpful to identify patients in whom an electrophysiologic study is useful for diagnosis of syncope...

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..The aim of our analysis is to assess gender differences in baseline characteristics, acute therapies, and clinical outcome in patients with acute ST-elevation myocardial infarction (STEMI) complicated by cardiogenic shock...

..This advantage was associated with an increase in major bleeding complications...

..Little is known about the influence of chronic antithrombotic therapy on treatment and clinical outcome in patients with acute ST-elevation myocardial infarction (STEMI)...

..A balloon angioplasty of his left anterior descending artery had been performed 12 years ago and two bare-metal stents had been implanted two months later for an early restenosis...

..However little is known about the impact of admission on weekend in hospitals with catheterisation laboratories...

..The aim of this study was to compare eptifibatide and abciximab as adjuncts to primary percutaneous coronary intervention (PCI)...

..We sought to investigate the impact of prior statin therapy on in-hospital outcome in patients presenting with acute non-ST-elevation myocardial infarction...

..The aim of the present prospective registry was to evaluate the efficacy and safety of eptifibatide in clinical practice...

..However, a significant number of patients do not receive aspirin after AMI. Little is known about why aspirin is withheld or the long-term outcome of these patients today...

..Percutaneous coronary intervention (PCI) early after thrombolysis (early PCI) in patients with ST-elevation myocardial infarction (STEMI) is currently advised by clinical guidelines, but little is known about its use in clinical practice...

..Our results seen in connection with the results of the randomized SHOCK study advocate an early invasive approach in younger patients with cardiogenic shock, while the best strategy in elderly patients is still a matter of debate...

..We sought to assess the effect of clopidogrel on one-year ischemic events in unselected patients with NSTEMI...

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..We sought to investigate the impact of an invasive treatment in elderly patients presenting with non-ST elevation myocardial infarction (NSTEMI) in clinical practice...

..55-5.44%). The outcome of seven centres differed significantly from the expectation. CONCLUSION: In comparisons of the outcome quality of hospitals, adjustment for the patients' baseline risk by an appropriate method is indispensable...

..We sought to assess the effect of clopidogrel on clinical events 1 year after discharge in survivors of ST-elevation myocardial infarction (STEMI) in clinical practice...

..The following study is based on data of the ALKK PCI registry and assesses the use of DES depending on patient characteristics, indication and coronary status comparing the treatment years 2003 and 2005...

..Little is known about the use of eptifibatide in this setting...

..However, it is unclear whether patients treated in interventional facilities with 24-h primary PCI service have lower rates of adverse events...

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..The aim was to assess clinical, angiographic and cardiovascular magnetic resonance (CMR) findings in patients with Takotsubo cardiomyopathy...

..This low risk along with the less invasive nature of the procedure should make CAS an attractive and perhaps preferred option for the treatment of these patients...

..Patients treated with SES for saphenous vein graft disease were compared with patients receiving SES in native vessel disease...

..Whether the relatively lower dose results in lower effectiveness of fibrinolytic agents versus primary percutaneous coronary interventions (PCI) in patients with higher body mass index (BMI) is not known...

..NCM identifies discontinuities in lines of ablation. Successful ablation of chronic AF is associated with continuity of linear lesions and good clinical technique demands a vigilant search for and closure of every gap...