Nezahat Yucel

Summary

Publications

  1. ncbi request reprint The effects of erdosteine on the activities of some metabolic enzymes during cisplatin-induced nephrotoxicity in rats
    H Ramazan Yilmaz
    Department of Medical Biology and Genetics, Faculty of Medicine, Suleyman Demirel University, 32260 Isparta, Turkey
    Pharmacol Res 50:287-90. 2004
  2. doi request reprint Anticlastogenic effect of caffeic acid phenethyl ester on cisplatin-induced chromosome aberrations in rat bone marrow cells
    H Ramazan Yilmaz
    Department of Medical Biology, Faculty of Medicine, Suleyman Demirel University, Isparta, Turkey
    Toxicol Ind Health 26:33-7. 2010
  3. ncbi request reprint Effect of 2,4-dichlorophenoxyacetic acid on the activities of some metabolic enzymes for generating pyridine nucleotide pool of cells from mouse liver
    H Ramazan Yilmaz
    Suleyman Demirel University, Faculty of Medicine, Department of Medical Biology and Genetics, Isparta, Turkey
    Toxicol Ind Health 21:231-7. 2005
  4. ncbi request reprint The activities of liver adenosine deaminase, xanthine oxidase, catalase, superoxide dismutase enzymes and the levels of malondialdehyde and nitric oxide after cisplatin toxicity in rats: protective effect of caffeic acid phenethyl ester
    H Ramazan Yilmaz
    Department of Medical Biology and Genetics, Faculty of Medicine, Suleyman Demirel University, Isparta, Turkey
    Toxicol Ind Health 21:67-73. 2005
  5. ncbi request reprint Protective effect of caffeic acid phenethyl ester (CAPE) on lipid peroxidation and antioxidant enzymes in diabetic rat liver
    H Ramazan Yilmaz
    Department of Medical Biology and Genetics, Suleyman Demirel University, Faculty of Medicine, and Isparta, Turkey
    J Biochem Mol Toxicol 18:234-8. 2004
  6. doi request reprint Protective role of caffeic acid phenethyl ester and erdosteine on activities of purine-catabolizing enzymes and level of nitric oxide in red blood cells of isoniazid-administered rats
    H R Yilmaz
    Department of Medical Biology, School of Medicine, Suleyman Demirel University, Isparta, Turkey
    Toxicol Ind Health 24:519-24. 2008
  7. ncbi request reprint The effects of n-3 polyunsaturated fatty acids by gavage on some metabolic enzymes of rat liver
    H Ramazan Yilmaz
    Department of Medical Biology and Genetics, Faculty of Medicine, Suleyman Demirel University, Isparta, Turkey
    Prostaglandins Leukot Essent Fatty Acids 71:131-5. 2004
  8. ncbi request reprint A preliminary study of the levels of testis oxidative stress parameters after MK-801-induced experimental psychosis model: protective effects of CAPE
    Birsen Ozyurt
    Gaziosmanpasa University, Faculty of Medicine, Department of Anatomy, Tokat, Turkey
    Toxicology 230:83-9. 2007
  9. ncbi request reprint Protective role of alpha-tocopherol and caffeic acid phenethyl ester on ischemia-reperfusion injury via nitric oxide and myeloperoxidase in rat kidneys
    Ahmet Gurel
    Department of Biochemistry, Faculty of Medicine, Zonguldak Karaelmas University, Zonguldak, Turkey
    Clin Chim Acta 339:33-41. 2004
  10. ncbi request reprint Caffeic acid phenethyl ester (CAPE) protects rat skeletal muscle against ischemia-reperfusion-induced oxidative stress
    Huseyin Ozyurt
    Gaziosmanpasa University, Faculty of Medicine, Department of Biochemistry, Tokat, Turkey
    Vascul Pharmacol 47:108-12. 2007

Collaborators

Detail Information

Publications30

  1. ncbi request reprint The effects of erdosteine on the activities of some metabolic enzymes during cisplatin-induced nephrotoxicity in rats
    H Ramazan Yilmaz
    Department of Medical Biology and Genetics, Faculty of Medicine, Suleyman Demirel University, 32260 Isparta, Turkey
    Pharmacol Res 50:287-90. 2004
    ..The results obtained suggested that the glucose metabolizing metabolic pathways of renal tissue were partially affected from cisplatin toxicity and erdosteine have some protective effects on these enzyme activities...
  2. doi request reprint Anticlastogenic effect of caffeic acid phenethyl ester on cisplatin-induced chromosome aberrations in rat bone marrow cells
    H Ramazan Yilmaz
    Department of Medical Biology, Faculty of Medicine, Suleyman Demirel University, Isparta, Turkey
    Toxicol Ind Health 26:33-7. 2010
    ..We have concluded that CAPE could prevent cisplatin-induced chromosome aberrations by establishing a potent free radical scavenger effect...
  3. ncbi request reprint Effect of 2,4-dichlorophenoxyacetic acid on the activities of some metabolic enzymes for generating pyridine nucleotide pool of cells from mouse liver
    H Ramazan Yilmaz
    Suleyman Demirel University, Faculty of Medicine, Department of Medical Biology and Genetics, Isparta, Turkey
    Toxicol Ind Health 21:231-7. 2005
    ..As a result, 2,4-D had an effect on the first cross maternal and their offsprings. The compound did not affect the parameters studied except MDH enzyme activity in the second and third generation of mice...
  4. ncbi request reprint The activities of liver adenosine deaminase, xanthine oxidase, catalase, superoxide dismutase enzymes and the levels of malondialdehyde and nitric oxide after cisplatin toxicity in rats: protective effect of caffeic acid phenethyl ester
    H Ramazan Yilmaz
    Department of Medical Biology and Genetics, Faculty of Medicine, Suleyman Demirel University, Isparta, Turkey
    Toxicol Ind Health 21:67-73. 2005
    ..The results obtained suggested that CAPE significantly attenuated the hepatotoxicity as an indirect target of cisplatin in an animal model of cisplatin-induced nephrotoxicity...
  5. ncbi request reprint Protective effect of caffeic acid phenethyl ester (CAPE) on lipid peroxidation and antioxidant enzymes in diabetic rat liver
    H Ramazan Yilmaz
    Department of Medical Biology and Genetics, Suleyman Demirel University, Faculty of Medicine, and Isparta, Turkey
    J Biochem Mol Toxicol 18:234-8. 2004
    ..It is likely that STZ-induced diabetes caused liver damage. In addition, LPO may be one of the molecular mechanisms involved in STZ-induced diabetic damage. CAPE can reduce LPO caused by STZ-induced diabetes...
  6. doi request reprint Protective role of caffeic acid phenethyl ester and erdosteine on activities of purine-catabolizing enzymes and level of nitric oxide in red blood cells of isoniazid-administered rats
    H R Yilmaz
    Department of Medical Biology, School of Medicine, Suleyman Demirel University, Isparta, Turkey
    Toxicol Ind Health 24:519-24. 2008
    ..CAPE and erdosteine may have protective potential in this process and they may become a promising drug in the prevention of this undesired side effect of INH...
  7. ncbi request reprint The effects of n-3 polyunsaturated fatty acids by gavage on some metabolic enzymes of rat liver
    H Ramazan Yilmaz
    Department of Medical Biology and Genetics, Faculty of Medicine, Suleyman Demirel University, Isparta, Turkey
    Prostaglandins Leukot Essent Fatty Acids 71:131-5. 2004
    ..01) except 6PGD activity. As a result, n-3 PUFA may regulate the metabolic function of liver effectively by increasing HK, G6PD, 6PGD, LDH, and MDH enzyme activities of rat liver when added in enough amounts to the regular diet...
  8. ncbi request reprint A preliminary study of the levels of testis oxidative stress parameters after MK-801-induced experimental psychosis model: protective effects of CAPE
    Birsen Ozyurt
    Gaziosmanpasa University, Faculty of Medicine, Department of Anatomy, Tokat, Turkey
    Toxicology 230:83-9. 2007
    ..The results showed that experimentally induced schizophrenia caused oxidative stress in testes of rats and treatment with CAPE reduced these harmful effects...
  9. ncbi request reprint Protective role of alpha-tocopherol and caffeic acid phenethyl ester on ischemia-reperfusion injury via nitric oxide and myeloperoxidase in rat kidneys
    Ahmet Gurel
    Department of Biochemistry, Faculty of Medicine, Zonguldak Karaelmas University, Zonguldak, Turkey
    Clin Chim Acta 339:33-41. 2004
    ....
  10. ncbi request reprint Caffeic acid phenethyl ester (CAPE) protects rat skeletal muscle against ischemia-reperfusion-induced oxidative stress
    Huseyin Ozyurt
    Gaziosmanpasa University, Faculty of Medicine, Department of Biochemistry, Tokat, Turkey
    Vascul Pharmacol 47:108-12. 2007
    ..Whereas tissue CAT activity was not changed among groups. Our results indicate that CAPE has antioxidant properties similar to those of vit E in this model and may attenuate the harmful effects of hind limb I/R in skeletal muscle...
  11. ncbi request reprint Seroprevalence of hepatitis B and C viruses in the province of Tokat in the Black Sea region of Turkey: A population-based study
    Beytullah Yildirim
    Department of Gastroenterology, Gazi University, School of Medicine, Ankara, Turkey
    Turk J Gastroenterol 20:27-30. 2009
    ..In this study, we aimed to determine the seroprevalence of hepatitis B and hepatitis C as well as the frequency of isolated anti-HBc IgG positivity among a normal healthy population in a northern province of Turkey...
  12. doi request reprint Serum levels of natriuretic peptides in patients with Behcet's disease
    Ramazan Yagci
    Department of Ophthalmology, Fatih University, Medical School, Ankara, Turkey
    Clin Rheumatol 27:1153-8. 2008
    ..65 +/- 0.2 ng/ml, p = 0.017) and the healthy controls (0.8 +/- 0.27 ng/ml, p < 0.001). Our results suggest that changes in natriuretic peptide levels may be associated with vasculitis that play role in the etiopathogenesis of the BD...
  13. ncbi request reprint Experimentally induced acute sinusitis and efficacy of vitamin A
    Mehmet Guven
    Department of ORL, Faculty of Medicine, Gaziosmanpasa University, Tokat, Turkey
    Acta Otolaryngol 127:855-60. 2007
    ..We propose that antioxidant, anti-infective, immunomodulator vitamin A may be a useful addition in the management of sinusitis...
  14. doi request reprint Increased serum ferritin levels in patients with Crimean-Congo hemorrhagic fever: can it be a new severity criterion?
    Sener Barut
    Department of Infectious Diseases and Clinical Microbiology, Gaziosmanpasa University, 60100 Tokat, Turkey
    Int J Infect Dis 14:e50-4. 2010
    ..This study was designed to determine any correlation between serum ferritin and routine diagnostic laboratory markers of CCHF, and to investigate the relationship between serum ferritin levels and disease severity...
  15. ncbi request reprint Association between elevated aminotransferase levels and the metabolic syndrome in Northern Turkey
    Beytullah Yildirim
    Department of Gastroenterology, Gaziosmanpasa University, Tokat, Turkey
    Ann Hepatol 9:161-5. 2010
    ..We aimed to determine the prevalence of elevated ATLs and the association of elevated ATLs with the metabolic syndrome (MetS) in a northern province of Turkey...
  16. ncbi request reprint The effects of ginkgo biloba extract on tissue adenosine deaminase, xanthine oxidase, myeloperoxidase, malondialdehyde, and nitric oxide in cisplatin-induced nephrotoxicity
    Mukaddes Gulec
    Division of Biochemistry, Akyurt Integrated Unit of Ankara Numune Education and Research Hospital, Ankara, Turkey
    Toxicol Ind Health 22:125-30. 2006
    ..These results indicate that increased XO, AD and MPO activities, as well as MDA and NO levels play a critical role in cisplatin nephrotoxicity. GBE has been shown to protect against cisplatin-induced nephrotoxicity...
  17. ncbi request reprint The indices of endogenous oxidative and antioxidative processes in plasma from schizophrenic patients. The possible role of oxidant/antioxidant imbalance
    Omer Akyol
    Department of Biochemistry, Faculty of Medicine, Inonu University, Turgut Ozal Tip Merkezi, 44069 Malatya, Turkey
    Prog Neuropsychopharmacol Biol Psychiatry 26:995-1005. 2002
    ..These findings may also suggest some clues for the new treatment strategies with antioxidants and NO synthase (NOS) inhibitors in schizophrenia...
  18. ncbi request reprint Comparison of serum nitric oxide, malondialdehyde levels, and antioxidant enzyme activities in Behçet's disease with and without ocular disease
    Erdinc Aydin
    Department of Ophthalmology, Tulane University Health Sciences Center, New Orleans, LA, USA
    Ophthalmic Res 36:177-82. 2004
    ....
  19. ncbi request reprint PCR/RFLP-based cost-effective identification of SOD2 signal (leader) sequence polymorphism (Ala-9Val) using NgoM IV: a detailed methodological approach
    Omer Akyol
    Department of Medical Biology and Genetics, Firat University Medical Faculty, Elazig, Turkey
    Clin Chim Acta 345:151-9. 2004
    ..The enzyme proteins encoded by the different alleles have been suggested to have different activity patterns...
  20. ncbi request reprint Potential role of dietary omega-3 essential fatty acids on some oxidant/antioxidant parameters in rats' corpus striatum
    Mustafa Sarsilmaz
    Department of Anatomy, Faculty of Medicine, Firat University, Dekanlik Binasi, Elazig, Turkey
    Prostaglandins Leukot Essent Fatty Acids 69:253-9. 2003
    ..Taken together, this preliminary animal study provides strong support for a therapeutic effect of omega-3 EFA supplemented to classical neuroleptic regimen in the treatment of schizophrenic symptoms and tardive dyskinesia...
  21. ncbi request reprint The activities of serum adenosine deaminase and xanthine oxidase enzymes in Behcet's disease
    Sadik Sogut
    Department of Biochemistry, Faculty of Medicine, Inonu University, Turgut Ozal Medical Center, 44069 Malatya, Turkey
    Clin Chim Acta 325:133-8. 2002
    ..The aim of this prospective study was to evaluate whether there are changes in serum AD activity as an index of T lymphocyte function in Behcet's disease (BD) which is known as having T cell-mediated immune response...
  22. doi request reprint Gradual detorsion of torsioned rat testis attenuates ischemia reperfusion injury
    Bulent Akcora
    Department of Pediatric Surgery, Faculty of Medicine, Mustafa Kemal University, Hatay, Turkey
    J Pediatr Surg 43:1879-84. 2008
    ..This study was designed to investigate effect of gradual detorsion on testicular ischemia reperfusion injury...
  23. ncbi request reprint Association between Ala-9Val polymorphism of Mn-SOD gene and schizophrenia
    Omer Akyol
    Department of Medical Biology and Genetics, Firat University Medical School, Elazig, Turkey
    Prog Neuropsychopharmacol Biol Psychiatry 29:123-31. 2005
    ..Further investigations are warranted in larger populations with other susceptible genes that might be associated with schizophrenia...
  24. ncbi request reprint Antioxidant status, lipid peroxidation and nitric oxide in fibromyalgia: etiologic and therapeutic concerns
    Salih Ozgocmen
    Division of Rheumatology, Department of Physical Medicine and Rehabilitation, Faculty of Medicine, Firat University, 23119 Elazig, Turkey
    Rheumatol Int 26:598-603. 2006
    ..These findings represent a rationale for further research assessing the effect of free radical scavengers or antioxidant agents like vitamins and omega-3 fatty acids on peripheral and central mechanisms in FM...
  25. doi request reprint Ameliorative effect of caffeic acid phenethyl ester on histopathological and biochemical changes induced by cigarette smoke in rat kidney
    Hidir Pekmez
    Department of Anatomy, Faculty of Medicine, Elazig School of Health Sciences, Firat University, Elazig, Turkey
    Toxicol Ind Health 26:175-82. 2010
    ..The present findings indicate that cigarette smoke causes impairment in renal structure and function, which can be prevented by CAPE administration...
  26. ncbi request reprint [The relation between nitric oxide levels in exhaled breath condensate and asthma control questionnaires in asthma patients]
    Hüsamettin Sazlidere
    Department of Chest Diseases, Faculty of Medicine, Gaziosmanpasa University, Tokat, Turkey
    Tuberk Toraks 58:5-15. 2010
    ..It was concluded that the currently available asthma control questionnaires may be adequate for assessing asthma control...
  27. doi request reprint Increased frequency of familial Mediterranean fever in northern Turkey: a population-based study
    Bunyamin Kisacik
    Division of Rheumatology, Department of Internal Medicine, Faculty of Medicine, Gaziosmanpasa University, Tokat, Turkey
    Rheumatol Int 29:1307-9. 2009
    ..82%) which was higher than expected. This rate is the highest frequency of FMF reported from Turkey. Further large sample studies are needed to define to true prevalence of FMF in Turkey...
  28. ncbi request reprint Screening of family members of children with Familial Mediterranean Fever: true-autosomal and pseudo-autosomal inheritance
    Musa Kazim Caglar
    Department of Pediatrics, Faculty of Medicine, Abant Izzet Baysal University, Bolu, Turkey
    Acta Reumatol Port 33:415-20. 2008
    ..Screening of family members of children with Familial Mediterranean Fever (FMF) has been carried out to detect new potential patients and to analyze the type of inheritance other than autosomal recessive...
  29. doi request reprint Familial Mediterranean fever gene mutations in the inner northern region of Turkey and genotype-phenotype correlation in children
    Resul Yilmaz
    Department of Pediatrics, School of Medicine, Gaziosmanpasa University, Tokat, Turkey
    J Paediatr Child Health 45:641-5. 2009
    ..The aim of this study was to determine the most common mutations and clinical features, and their relationships...
  30. ncbi request reprint Current concepts in the pathophysiology of fibromyalgia: the potential role of oxidative stress and nitric oxide
    Salih Ozgocmen
    Division of Rheumatology, Department of Physical Medicine and Rehabilitation, Faculty of Medicine, Firat University, 23119 Elazig, Turkey
    Rheumatol Int 26:585-97. 2006
    ..These future researches will enhance our understanding of the complex pathophysiology of this disorder...