M I Yousef

Summary

Publications

  1. ncbi request reprint Biochemical study on the hypoglycemic effects of onion and garlic in alloxan-induced diabetic rats
    F M El-Demerdash
    Department of Environmental Studies, Institute of Graduate Studies and Research, Alexandria University, 163, Horreya Avenue, P O Box 832, Alexandria 21526, Egypt
    Food Chem Toxicol 43:57-63. 2005
  2. doi request reprint Protective role of propolis against reproductive toxicity of triphenyltin in male rabbits
    Mokhtar I Yousef
    Department of Home Economics, Faculty of Specific Education, Alexandria University, Alexandria, Egypt
    Food Chem Toxicol 48:1846-52. 2010
  3. doi request reprint Potential protective effects of quercetin and curcumin on paracetamol-induced histological changes, oxidative stress, impaired liver and kidney functions and haematotoxicity in rat
    Mokhtar I Yousef
    Department of Environmental Studies, Institute of Graduate Studies and Research, Alexandria University, Alexandria, Egypt
    Food Chem Toxicol 48:3246-61. 2010
  4. doi request reprint Protective effect of grape seed proanthocyanidin extract against oxidative stress induced by cisplatin in rats
    M I Yousef
    Department of Home Economic, Faculty of Specific Education, University of Alexandria, 14 Mohamed Amin Shohaib Street, Moustafa Kamel, P O Box Roushdi, Alexandria 21259, Egypt
    Food Chem Toxicol 47:1176-1183. 2009
  5. doi request reprint Sodium arsenite induced biochemical perturbations in rats: ameliorating effect of curcumin
    Mokhtar I Yousef
    Department of Home Economic, Faculty of Specific Education, Alexandria University, 14 Mohamed Amin Shohaib Street, Moustafa Kamel, P O Box Roushdi, Alexandria 21529, Egypt
    Food Chem Toxicol 46:3506-11. 2008
  6. ncbi request reprint An in vitro study on reproductive toxicity of aluminium chloride on rabbit sperm: the protective role of some antioxidants
    Mokhtar I Yousef
    Department of Environmental Studies, Institute of Graduate Studies and Research, Alexandria University, 163 Horreya Avenue, PO Box 832, El Chatby, Alexandria 21526, Egypt
    Toxicology 239:213-23. 2007
  7. doi request reprint Vitamin E modulates reproductive toxicity of pyrethroid lambda-cyhalothrin in male rabbits
    Mokhtar I Yousef
    Department of Home Economic, Faculty of Specific Education, Alexandria University, Alexandria, Egypt
    Food Chem Toxicol 48:1152-9. 2010
  8. ncbi request reprint Study of the protective effect of ascorbic acid against the toxicity of stannous chloride on oxidative damage, antioxidant enzymes and biochemical parameters in rabbits
    M I Yousef
    Department of Environmental Studies, Institute of Graduate Studies and Research, Alexandria University, Alexandria, Egypt
    Toxicology 235:194-202. 2007
  9. doi request reprint Propolis protection from reproductive toxicity caused by aluminium chloride in male rats
    Mokhtar I Yousef
    Department of Home Economic, Faculty of Specific Education, Alexandria University, 14 Mohamed Amin Shohaib Street, Moustafa Kamel, P O Box Roushdi, Alexandria 21529, Egypt
    Food Chem Toxicol 47:1168-75. 2009
  10. ncbi request reprint Protective role of ascorbic acid to enhance semen quality of rabbits treated with sublethal doses of aflatoxin B(1)
    M H Salem
    Department of Animal Production, Faculty of Agriculture, El-Shatby, Alexandria University, Alexandria, Egypt
    Toxicology 162:209-18. 2001

Collaborators

Detail Information

Publications38

  1. ncbi request reprint Biochemical study on the hypoglycemic effects of onion and garlic in alloxan-induced diabetic rats
    F M El-Demerdash
    Department of Environmental Studies, Institute of Graduate Studies and Research, Alexandria University, 163, Horreya Avenue, P O Box 832, Alexandria 21526, Egypt
    Food Chem Toxicol 43:57-63. 2005
    ..The present results showed that garlic and onion juices exerted antioxidant and antihyperglycemic effects and consequently may alleviate liver and renal damage caused by alloxan-induced diabetes...
  2. doi request reprint Protective role of propolis against reproductive toxicity of triphenyltin in male rabbits
    Mokhtar I Yousef
    Department of Home Economics, Faculty of Specific Education, Alexandria University, Alexandria, Egypt
    Food Chem Toxicol 48:1846-52. 2010
    ..Furthermore, the presence of propolis with TPTCl alleviates its toxic effects. From the present study, it can be concluded propolis can be effective in the protection of TPTCl-induced reproductive toxicity...
  3. doi request reprint Potential protective effects of quercetin and curcumin on paracetamol-induced histological changes, oxidative stress, impaired liver and kidney functions and haematotoxicity in rat
    Mokhtar I Yousef
    Department of Environmental Studies, Institute of Graduate Studies and Research, Alexandria University, Alexandria, Egypt
    Food Chem Toxicol 48:3246-61. 2010
    ..Therefore, it can be concluded that concomitant administration of quercetin or curcumin with paracetamol may be useful in reversing the toxicity of the drug compared to N-acetylcysteine...
  4. doi request reprint Protective effect of grape seed proanthocyanidin extract against oxidative stress induced by cisplatin in rats
    M I Yousef
    Department of Home Economic, Faculty of Specific Education, University of Alexandria, 14 Mohamed Amin Shohaib Street, Moustafa Kamel, P O Box Roushdi, Alexandria 21259, Egypt
    Food Chem Toxicol 47:1176-1183. 2009
    ..Therefore, the present results revealed that GSPE exerts a protective effect by antagonizing cisplatin toxicity...
  5. doi request reprint Sodium arsenite induced biochemical perturbations in rats: ameliorating effect of curcumin
    Mokhtar I Yousef
    Department of Home Economic, Faculty of Specific Education, Alexandria University, 14 Mohamed Amin Shohaib Street, Moustafa Kamel, P O Box Roushdi, Alexandria 21529, Egypt
    Food Chem Toxicol 46:3506-11. 2008
    ..Experimental results, therefore suggested that curcumin protects arsenic induced biochemical alterations in rats...
  6. ncbi request reprint An in vitro study on reproductive toxicity of aluminium chloride on rabbit sperm: the protective role of some antioxidants
    Mokhtar I Yousef
    Department of Environmental Studies, Institute of Graduate Studies and Research, Alexandria University, 163 Horreya Avenue, PO Box 832, El Chatby, Alexandria 21526, Egypt
    Toxicology 239:213-23. 2007
    ..The antioxidants revealed protective effects against the cytotoxicity of AlCl(3)...
  7. doi request reprint Vitamin E modulates reproductive toxicity of pyrethroid lambda-cyhalothrin in male rabbits
    Mokhtar I Yousef
    Department of Home Economic, Faculty of Specific Education, Alexandria University, Alexandria, Egypt
    Food Chem Toxicol 48:1152-9. 2010
    ..It was suggested that LCT exerted a significant adverse effect on reproductive performance of male rabbits. Furthermore, vitamin E antagonized the toxic effects of LCT and improved semen quality of male rabbit...
  8. ncbi request reprint Study of the protective effect of ascorbic acid against the toxicity of stannous chloride on oxidative damage, antioxidant enzymes and biochemical parameters in rabbits
    M I Yousef
    Department of Environmental Studies, Institute of Graduate Studies and Research, Alexandria University, Alexandria, Egypt
    Toxicology 235:194-202. 2007
    ..Also, the presence of AA with SnCl2 alleviated its harmful effects on most of the tested parameters. Therefore, the present results revealed that treatment with AA could minimize the toxic effects of stannous chloride...
  9. doi request reprint Propolis protection from reproductive toxicity caused by aluminium chloride in male rats
    Mokhtar I Yousef
    Department of Home Economic, Faculty of Specific Education, Alexandria University, 14 Mohamed Amin Shohaib Street, Moustafa Kamel, P O Box Roushdi, Alexandria 21529, Egypt
    Food Chem Toxicol 47:1168-75. 2009
    ..This was proved histopathologically by the great improvement in testes. In conclusion propolis could be effective in the protection against the reproductive toxicity of AlCl3...
  10. ncbi request reprint Protective role of ascorbic acid to enhance semen quality of rabbits treated with sublethal doses of aflatoxin B(1)
    M H Salem
    Department of Animal Production, Faculty of Agriculture, El-Shatby, Alexandria University, Alexandria, Egypt
    Toxicology 162:209-18. 2001
    ..Results demonstrated the beneficial influences of AA in reducing the negative effects of AFB(1) on production and reproduction of male rabbits...
  11. ncbi request reprint Stannous chloride induces alterations in enzyme activities, lipid peroxidation and histopathology in male rabbit: antioxidant role of vitamin C
    F M El-Demerdash
    Department of Environmental Studies, Institute of Graduate Studies and Research, University of Alexandria, Alexandria 21526, Egypt
    Food Chem Toxicol 43:1743-52. 2005
    ..Bowman's space of kidney was almost normal, with normal lining of proximal and distal convoluted tubules. In conclusion AA could be effective in the protection against stannous chloride toxicity...
  12. ncbi request reprint Role of alpha-tocopherol and beta-carotene in ameliorating the fenvalerate-induced changes in oxidative stress, hemato-biochemical parameters, and semen quality of male rats
    F M El-Demerdash
    Department of Environmental Studies, Institute of Graduate Studies and Research, Alexandria University, Alexandria, Egypt
    J Environ Sci Health B 39:443-59. 2004
    ..The obtained results demonstrated the beneficial influences of vitamin E, beta-carotene alone and/or in combination in reducing the harmful effects of fenvalerate...
  13. ncbi request reprint Effect of ascorbic acid and Vitamin E supplementation on semen quality and biochemical parameters of male rabbits
    M I Yousef
    Department of Environmental Studies, Institute of Graduate Studies and Research, Alexandria University, 163 Horreya Avenue, P O Box 832, Alexandria 21526, Egypt
    Anim Reprod Sci 76:99-111. 2003
    ..E and their combination reduced the production of free radicals and can improve rabbit semen quality, but the greater improvement seemed to be from Vit. E...
  14. ncbi request reprint Protective role of isoflavones against the toxic effect of cypermethrin on semen quality and testosterone levels of rabbits
    M I Yousef
    Department of Environmental Studies, Institute of Graduate Studies and Research, Alexandria University, Alexandria, Egypt
    J Environ Sci Health B 38:463-78. 2003
    ..Interestingly, data showed that isoflavones alone caused an improvement in some semen quality and had no negative effects on male fertility, and did not have negative effects on male fertility...
  15. ncbi request reprint Changes in some hematological and biochemical indices of rabbits induced by isoflavones and cypermethrin
    M I Yousef
    Department of Environmental Studies, Institute of Graduate Studies and Research, Alexandria University, 163, Horreya Avenue, P O Box 832, Alexandria 21526, Egypt
    Toxicology 189:223-34. 2003
    ..Results demonstrated the beneficial influences of isoflavones in reducing the negative effects of cypermethrin on blood hematology and biochemical parameters of male rabbits...
  16. ncbi request reprint A sensitive sperm-motility test for the assessment of cytotoxic effect of pesticides
    M I Yousef
    Department of Environmental Studies, Alexandria University, Egypt
    J Environ Sci Health B 31:99-115. 1996
    ..Additionally, the use of rabbit sperm is a more sensitive test system than human sperm. This study suggests that the rabbit sperm test appears to have a potential for the assessment of toxicity on human reproduction...
  17. doi request reprint Ameliorating effect of curcumin on sodium arsenite-induced oxidative damage and lipid peroxidation in different rat organs
    Fatma M El-Demerdash
    Department of Environmental Studies, Institute of Graduate Studies and Research, Alexandria University, 163 Horreya Avenue, P O Box 832, Alexandria 21526, Egypt
    Food Chem Toxicol 47:249-54. 2009
    ..The presence of curcumin with Sa alleviated its toxic effects. It can be concluded that curcumin has beneficial influences and could be able to antagonize Sa toxicity...
  18. ncbi request reprint Alterations of lipid profile in plasma and liver of diabetic rats: effect of hypoglycemic herbs
    Al Sayeda A Newairy
    Department of Biochemistry, Faculty of Science, Alexandria University, Egypt
    J Environ Sci Health B 37:475-84. 2002
    ..Moreover, the Kammun Quaramany showed the most potent effect...
  19. ncbi request reprint Protective effects of isoflavone on some biochemical parameters affected by cypermethrin in male rabbits
    F M El-Demerdash
    Department of Environmental Studies, Institute of Graduate Studies and Research, Alexandria University, Alexandria, Egypt
    J Environ Sci Health B 38:365-78. 2003
    ..Results concluded that isoflavone confers marked protection against cypermethrin-induced oxidative stress in rabbit's plasma, liver, brain and testes...
  20. ncbi request reprint Acrylamide-induced oxidative stress and biochemical perturbations in rats
    M I Yousef
    Department of Environmental Studies, Institute of Graduate Studies and Research, Alexandria University, Alexandria, Egypt
    Toxicology 219:133-41. 2006
    ..The present results showed that different doses of acrylamide exerted deterioration effects on enzyme activities and lipid peroxidation in a dose-dependent manner...
  21. ncbi request reprint Effect of some hypoglycemic herbs on the activity of phase I and II drug-metabolizing enzymes in alloxan-induced diabetic rats
    S A Sheweita
    Department of Bioscience and Technology, Institute of Graduate Studies and Research, Alexandria University, Egypt
    Toxicology 174:131-9. 2002
    ..Such alterations in the activity of phase I and II drug-metabolizing enzymes should be considered when therapeutic drugs are administered to diabetic patients since most of drugs are metabolized mainly by the cytochrome P450 system...
  22. ncbi request reprint Effect of dietary zinc deficiency on hematological and biochemical parameters and concentrations of zinc, copper, and iron in growing rats
    H A El Hendy
    Department of Home Economics, Faculty of Agriculture, El-Shatby, Alexandria University, Alexandria, Egypt
    Toxicology 167:163-70. 2001
    ..These results showed that Zn deficiency has negative effects on growth rate, specific organ weights, hematological parameters, and serum levels of Zn, Cu and Fe, especially in rats fed the lowest Zn level...
  23. ncbi request reprint Dietary zinc deficiency induced-changes in the activity of enzymes and the levels of free radicals, lipids and protein electrophoretic behavior in growing rats
    M I Yousef
    Department of Environmental Studies, Institute of Graduate Studies and Research, Alexandria University, 163 Horreya Avenue, P O Box 832, Alexandria 21526, Egypt
    Toxicology 175:223-34. 2002
    ..From the results of this study it can be concluded that Zn deficiency exerts numerous alterations in the studied biochemical parameters, protein pattern, and increased lipid peroxidation...
  24. ncbi request reprint Propolis alleviates aluminium-induced lipid peroxidation and biochemical parameters in male rats
    Al Sayeda A Newairy
    Department of Biochemistry, Faculty of Science, Alexandria University, Alexandria, Egypt
    Food Chem Toxicol 47:1093-8. 2009
    ..The presence of propolis with AlCl3 alleviated its toxic effects in rats treated with AlCl3. It can be concluded that propolis has beneficial influences and could be able to antagonize AlCl3 toxicity...
  25. ncbi request reprint Influence of ascorbic acid supplementation on the haematological and clinical biochemistry parameters of male rabbits exposed to aflatoxin B1
    M I Yousef
    Department of Environmental Studies, Institute of Graduate Studies and Research, Faculty of Agriculture, El Shatby, Alexandria University, Alexandria, Egypt
    J Environ Sci Health B 38:193-209. 2003
    ..Also, the presence of AA could diminished the adverse effects of AFB1 on most of hematological and biochemical values, and enzymatic activities in rabbits...
  26. ncbi request reprint Toxic effects of carbofuran and glyphosate on semen characteristics in rabbits
    M I Yousef
    Department of Environmental Studies, University of Alexandria, Egypt
    J Environ Sci Health B 30:513-34. 1995
    ..These effects on sperm quality may be due to the direct cytotoxic effects of these pesticides on spermatogenesis and/or indirectly via hypothalami-pituitary-testis axis which control the reproductive efficiency...
  27. ncbi request reprint Influence of paraquat, glyphosate, and cadmium on the activity of some serum enzymes and protein electrophoretic behavior (in vitro)
    F M El Demerdash
    Department of Environmental Studies, Institute of Graduate Studies and Research, Alexandria University, Egypt
    J Environ Sci Health B 36:29-42. 2001
    ..The results suggest that the in vitro enzyme-activity test seems to have a potential for the assessment of pesticide and heavy metal toxicity...
  28. ncbi request reprint Ameliorating effect of folic acid on chromium(VI)-induced changes in reproductive performance and seminal plasma biochemistry in male rabbits
    Mokhtar I Yousef
    Department of Environmental Studies, Institute of Graduate Studies and Research, University of Alexandria, 163, Horreya Avenue, P O Box 832, Alexandria 21526, Egypt
    Reprod Toxicol 21:322-8. 2006
    ..FA alone significantly increased BW, RTW, REW, semen characteristics and seminal plasma enzymes, and decreased the levels of free radicals. Furthermore, FA can be effective in the protection of chromium-induced reproductive toxicity...
  29. ncbi request reprint Aluminium-induced changes in hemato-biochemical parameters, lipid peroxidation and enzyme activities of male rabbits: protective role of ascorbic acid
    Mokhtar I Yousef
    Department of Environmental Studies, Institute of Graduate Studies and Research, University of Alexandria, 163 Horreya Avenue, P O Box 832, Alexandria 21526, Egypt
    Toxicology 199:47-57. 2004
    ..While, the rest of the tested parameters were not affected. Also, the present study showed that ascorbic acid can be effective in the protection of aluminium-induced toxicity...
  30. ncbi request reprint Antioxidant activities and lipid lowering effects of isoflavone in male rabbits
    Mokhtar I Yousef
    Department of Environmental Studies, Institute of Graduate Studies and Research, Alexandria University, 163, Horreya Avenue, P O Box 832, Alexandria 21526, Egypt
    Food Chem Toxicol 42:1497-503. 2004
    ..While the level of high density lipoprotein (HDL) increased by 29% and 32%. The present results showed that the 5 mg/kg dose of isoflavone seemed to be related to a better plasma lipid and lipoprotein profiles and antioxidant activity...
  31. ncbi request reprint Cadmium-induced changes in lipid peroxidation, blood hematology, biochemical parameters and semen quality of male rats: protective role of vitamin E and beta-carotene
    Fatma M El-Demerdash
    Department of Environmental Studies, Institute of Graduate Studies and Research, University of Alexandria, 163, Horreya Avenue, P O Box 832, Alexandria 21526, Egypt
    Food Chem Toxicol 42:1563-71. 2004
    ..Results demonstrated the beneficial influences of vitamin E, -carotene alone and/or in combination in reducing the harmful effects of CdCl2...
  32. ncbi request reprint Effect of isoflavones on reproductive performance, testosterone levels, lipid peroxidation, and seminal plasma biochemistry of male rabbits
    Mokhtar I Yousef
    Department of Environmental Studies, Institute of Graduate Studies and Research, Alexandria University, Alexandria, Egypt
    J Environ Sci Health B 39:819-33. 2004
    ..The present results showed that either 2.5 mg/kg BW or 5 mg/kg BW doses of isoflavones caused an improvement of some semen characteristics and did not have negative effects on male fertility...
  33. ncbi request reprint Reproductive performance, blood testosterone, lipid peroxidation and seminal plasma biochemistry of rabbits as affected by feeding Acacia saligna under subtropical conditions
    Mokhtar I Yousef
    Department of Environmental Studies, Institute of Graduate Studies and Research, Alexandria University, 163 Horreya Avenue, PO Box 832, Alexandria 21526, Egypt
    Food Chem Toxicol 43:333-9. 2005
    ..It can be concluded that up to 40% Acacia leaves could be used successfully and safely in the diet of rabbits without adversely affecting their reproductive performance under subtropical conditions...
  34. ncbi request reprint Deltamethrin-induced oxidative damage and biochemical alterations in rat and its attenuation by Vitamin E
    Mokhtar I Yousef
    Department of Environmental Studies, Institute of Graduate Studies and Research, Alexandria University, 163, Horreya Avenue, P O Box 832, Alexandria 21526, Egypt
    Toxicology 227:240-7. 2006
    ..05) decreased. The present study revealed that the presence of Vitamin E could diminish the adverse effects of deltamethrin on most of biochemical parameters, lipid peroxidation and enzyme activities in rats...
  35. ncbi request reprint Biochemical study on the protective role of folic acid in rabbits treated with chromium (VI)
    Fatma M El-Demerdash
    Department of Environmental Studies, Institute of Graduate Studies and Research, Alexandria University, Egypt
    J Environ Sci Health B 41:731-46. 2006
    ..The presence of FA with Cr(VI) restored the changes in enzyme activities and biochemical parameters. In conclusion, folic acid could be effective in the protection of chromium-induced toxicity...
  36. ncbi request reprint Aluminium-induced deterioration in reproductive performance and seminal plasma biochemistry of male rabbits: protective role of ascorbic acid
    Mokhtar I Yousef
    Department of Environmental Studies, Institute of Graduate Studies and Research, Alexandria University, 163 Horreya Avenue, P O Box 832, Alexandria 21526, Egypt
    Toxicology 215:97-107. 2005
    ..It was suggested that AlCl3 exerted a significant adverse effect on reproductive performance of male rabbits. Furthermore, AA could be able to antagonize the toxic effects of AlCl3 and improved semen quality of male rabbit...
  37. ncbi request reprint Protective role of ascorbic acid to enhance reproductive performance of male rabbits treated with stannous chloride
    Mokhtar I Yousef
    Department of Environmental Studies, Institute of Graduate Studies and Research, University of Alexandria, 163 Horreya Avenue, P O Box 832, Alexandria 21526, Egypt
    Toxicology 207:81-9. 2005
    ..Also, the beneficial influences of AA in counteracting the toxic effects of SnCl2 and improved the reproductive performance of male rabbit was demonstrated...
  38. ncbi request reprint Biochemical study on the effects of some Egyptian herbs in alloxan-induced diabetic rats
    Hamdy A Mansour
    Department of Biochemistry, Faculty of Science, Alexandria University, 21526, Alexandria, Egypt
    Toxicology 170:221-8. 2002
    ..The present results showed that the herb suspensions exerted antihyperglycemic effects and consequently may alleviate liver and renal damage caused by alloxan-induced diabetes...