Orie Yoshinari

Summary

Publications

  1. doi request reprint Safety and toxicological evaluation of a novel, water-soluble undenatured type II collagen
    Orie Yoshinari
    Development Division, Ryusendo Co Ltd, Tokyo, Japan
    Toxicol Mech Methods 23:491-9. 2013
  2. doi request reprint Trigonelline ameliorates oxidative stress in type 2 diabetic Goto-Kakizaki rats
    Orie Yoshinari
    The United Graduate School of Agricultural Science, Iwate University, Iwate, Japan
    J Med Food 16:34-41. 2013
  3. pmc Anti-obesity effects of onion extract in Zucker diabetic fatty rats
    Orie Yoshinari
    Faculty of Agriculture, Yamagata University, Tsuruoka, Yamagata 997 8555, Japan
    Nutrients 4:1518-26. 2012
  4. ncbi request reprint Anti-diabetic effects of pumpkin and its components, trigonelline and nicotinic acid, on Goto-Kakizaki rats
    Orie Yoshinari
    Course of the Science of Bioresource, The United Graduate School of Agricultural Science, Iwate University, Morioka, Iwate, Japan
    Biosci Biotechnol Biochem 73:1033-41. 2009
  5. ncbi request reprint Anti-diabetic effect of trigonelline and nicotinic acid, on KK-A(y) mice
    O Yoshinari
    Course on the Science of Bioresource, The United Graduate School of Agricultural Science, Iwate University, 3 18 8 Ueda, Morioka, Iwate 020 8550, Japan
    Curr Med Chem 17:2196-202. 2010
  6. doi request reprint Anti-diabetic effect of pyroglutamic acid in type 2 diabetic Goto-Kakizaki rats and KK-Ay mice
    Orie Yoshinari
    Course of the Science of Bioresource, The United Graduate School of Agricultural Science, Iwate University, Morioka, Iwate 020 8550, Japan
    Br J Nutr 106:995-1004. 2011
  7. ncbi request reprint Hepatoprotective effect of germanium-containing Spirulina in rats with (D)-galactosamine- and lipopolysaccharide-induced hepatitis
    Orie Yoshinari
    Department of Bioresource Engineering, Faculty of Agriculture, Yamagata University, Yamagata 997 8555, Japan
    Br J Nutr 111:135-40. 2014
  8. ncbi request reprint Water-soluble undenatured type II collagen ameliorates collagen-induced arthritis in mice
    Orie Yoshinari
    1 Development Division, Ryusendo Co Ltd, Toshimaku, Tokyo, Japan
    J Med Food 16:1039-45. 2013
  9. ncbi request reprint Effects of dietary catechins on glucose tolerance, blood pressure and oxidative status in Goto-Kakizaki rats
    Kiharu Igarashi
    Department of Bioresource Engineering, Faculty of Agriculture, Yamagata University, Yamagata, Japan
    J Nutr Sci Vitaminol (Tokyo) 53:496-500. 2007

Detail Information

Publications9

  1. doi request reprint Safety and toxicological evaluation of a novel, water-soluble undenatured type II collagen
    Orie Yoshinari
    Development Division, Ryusendo Co Ltd, Tokyo, Japan
    Toxicol Mech Methods 23:491-9. 2013
    ..Also, no dose-dependent toxicity was observed. Furthermore, colony sizing showed no clastogenic effects induced by NEXT-II under the experimental conditions. These studies demonstrated the broad spectrum of safety of NEXT-II...
  2. doi request reprint Trigonelline ameliorates oxidative stress in type 2 diabetic Goto-Kakizaki rats
    Orie Yoshinari
    The United Graduate School of Agricultural Science, Iwate University, Iwate, Japan
    J Med Food 16:34-41. 2013
    ..These results suggested that mitigation of diabetes by TRG is mediated by its ameliorating effects on oxidative stress...
  3. pmc Anti-obesity effects of onion extract in Zucker diabetic fatty rats
    Orie Yoshinari
    Faculty of Agriculture, Yamagata University, Tsuruoka, Yamagata 997 8555, Japan
    Nutrients 4:1518-26. 2012
    ....
  4. ncbi request reprint Anti-diabetic effects of pumpkin and its components, trigonelline and nicotinic acid, on Goto-Kakizaki rats
    Orie Yoshinari
    Course of the Science of Bioresource, The United Graduate School of Agricultural Science, Iwate University, Morioka, Iwate, Japan
    Biosci Biotechnol Biochem 73:1033-41. 2009
    ..This suggests that the regulation of these enzyme activities by TRG and NA was closely related to the suppression of both TG accumulation and the progression of diabetes...
  5. ncbi request reprint Anti-diabetic effect of trigonelline and nicotinic acid, on KK-A(y) mice
    O Yoshinari
    Course on the Science of Bioresource, The United Graduate School of Agricultural Science, Iwate University, 3 18 8 Ueda, Morioka, Iwate 020 8550, Japan
    Curr Med Chem 17:2196-202. 2010
    ....
  6. doi request reprint Anti-diabetic effect of pyroglutamic acid in type 2 diabetic Goto-Kakizaki rats and KK-Ay mice
    Orie Yoshinari
    Course of the Science of Bioresource, The United Graduate School of Agricultural Science, Iwate University, Morioka, Iwate 020 8550, Japan
    Br J Nutr 106:995-1004. 2011
    ..From these results, it is suggested that dietary PA beneficially modifies glucose and lipid metabolism in diabetic animals, and can potentially contribute to the mitigation of T2DM...
  7. ncbi request reprint Hepatoprotective effect of germanium-containing Spirulina in rats with (D)-galactosamine- and lipopolysaccharide-induced hepatitis
    Orie Yoshinari
    Department of Bioresource Engineering, Faculty of Agriculture, Yamagata University, Yamagata 997 8555, Japan
    Br J Nutr 111:135-40. 2014
    ..These results suggest that GeSP could afford a significant protective effect in the alleviation of GalN/LPS-induced hepatic damage. In addition, the results indicate that GeSP is more effective than SP...
  8. ncbi request reprint Water-soluble undenatured type II collagen ameliorates collagen-induced arthritis in mice
    Orie Yoshinari
    1 Development Division, Ryusendo Co Ltd, Toshimaku, Tokyo, Japan
    J Med Food 16:1039-45. 2013
    ..These results demonstrated that orally administered water-soluble undenatured C II (NEXT-II) is highly efficacious in the suppression of CIA by inducing CD4+CD25+ Treg cells...
  9. ncbi request reprint Effects of dietary catechins on glucose tolerance, blood pressure and oxidative status in Goto-Kakizaki rats
    Kiharu Igarashi
    Department of Bioresource Engineering, Faculty of Agriculture, Yamagata University, Yamagata, Japan
    J Nutr Sci Vitaminol (Tokyo) 53:496-500. 2007
    ..From these results it is concluded that dietary catechins may be effective in delaying the progression of diabetes and the associated oxidative stress...